Cell Biology

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First biohybrid model of human ventricles is an important step forward for organ biofabrication

Heart disease - the leading cause of death in the U.S. - is so deadly in part because the heart, unlike other organs, cannot repair itself after injury.

8 Jul 2022

Scientists uncover how the innate immune system detects and fights HIV-1

Human immunodeficiency virus 1, more commonly known as HIV-1, is known for its uncanny ability to evade the immune system.

8 Jul 2022

Study offers a new understanding of the evolutionary diversification of KNL2 gene

In living organisms cells divide and reproduce in two ways, mitosis and meiosis. Mitosis results in two identical daughter cells, whereas meiosis results in four sex cells.

8 Jul 2022

Study finds microglia to be responsible for neuronal death in a mitochondrial disease animal model

Microglia, a type of central nervous system cell, is primarily responsible for neuronal death in Leigh Syndrome and the neurological symptoms related to this mitochondrial disease.

8 Jul 2022

Commercial antibodies do not recognize immune receptor ACKR1

Antibodies are among the most frequently used tools in the biosciences, as they enable researchers to identify molecules.

8 Jul 2022

Disrupting genes in the yeast Pichia pastori to increase its secretory production of useful proteins

A collaboration including researchers from Kobe University, University of Tokyo and Tohoku University has successfully identified and disrupted genes in the yeast Pichia pastoris (1) in order to increase its secretory production of useful proteins (2).

8 Jul 2022

IMBA researchers uncover basic principles of early development using blastoids

One often thinks that the early embryo is fragile and needs support. However, at the earliest stages of development, it has the power to feed the future placenta and instructs the uterus so that it can nest.

7 Jul 2022

Scientists identify molecules promoting plant immunity

Two studies published by researchers at the Max Planck Institute for Plant Breeding Research in Cologne, Germany in collaboration with colleagues in China have discovered natural cellular molecules that drive critical plant immune responses.

7 Jul 2022

The Life Sciences; Where are we now, and where are we going?

As part of our SLAS Europe 2022 coverage, we spoke to Gerrit Gutzke and Michael Bussmann from Azenta Life Sciences about the products they offer for life sciences research.

From Society for Laboratory Automation and Screening (SLAS) 7 Jul 2022

MIT chemists discover how changes in a shape-shifting receptor trigger cell growth

Receptors found on cell surfaces bind to hormones, proteins, and other molecules, helping cells respond to their environment.

6 Jul 2022

Vaccine generates antibodies that target SARS-CoV-2 spike protein regions shared among many coronaviruses

Could the SARS-CoV-2 vaccine reawaken previous antibody responses and point the way to a universal coronavirus vaccine? A new analysis of the antibody response to a COVID-19 vaccine suggests the immune system's history with other coronaviruses, including those behind the common cold, shapes the patient's response, according to a study published today in Cell Reports.

6 Jul 2022

Researchers challenge centuries-old beliefs about limb regeneration

Ken Muneoka is no stranger to disrupting the field of regeneration; for example, in a 2019 ground-breaking publication in Nature, the Texas A&M University College of Veterinary Medicine & Biomedical Sciences professor proved for the first time that joint regeneration in mammals was possible.

6 Jul 2022

Running faster and dreaming help your left brain and right brain to communicate better

You’re out jogging and suddenly notice a low-hanging tree branch in your path. You quickly lower your head, narrowly avoiding the branch, and continue on the run without giving it another thought.

6 Jul 2022

Study yields molecular clues that could lead to new treatments for rare genetic disease

A new stem cell study by KAUST researchers helps to explain a rare genetic disease called Wiskott-Aldrich syndrome (WAS), yielding molecular clues that could lead to new treatments for a devastating immune deficiency disorder.

6 Jul 2022

Genetically engineered kidney organoids solve mystery of a rare disease

Researchers have solved a medical mystery in a poorly understood disease by uncovering which cells cause tumors in patients with tuberous sclerosis complex (TSC).

6 Jul 2022

"Selfish chromosomes" explain why most human embryos die very early on, study suggests

New research by a scientist at the Milner Center for Evolution at the University of Bath suggests that "selfish chromosomes" explain why most human embryos die very early on. The study, published in PLoS, Biology, explaining why fish embryos are fine but sadly humans' embryos often don't survive, has implications for the treatment of infertility.

6 Jul 2022

Gene defect underlying Krabbe disease causes degeneration of neurons directly, study finds

The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a new study publishing July 5th in the open-access journal PLOS Biology by Daesung Shin of the University at Buffalo, U.S. and colleagues.

5 Jul 2022

Researchers explore how diet and feeding patterns affect intestinal microbes

An estimated 500 to 1,000 bacterial species reside in each person's gut, perhaps numbering 100,000 trillion microorganisms.

5 Jul 2022

Study opens up a new avenue for the development of selective drug therapies

Researchers at the Department of Energy's Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins important in plant-microbe biology to a cancer trigger in humans, knowledge that had eluded scientists for decades.

5 Jul 2022

Study identifies a molecule that boosts fat burning

A study led by the University of Bonn has identified a molecule - the purine inosine - that boosts fat burning in brown adipocytes.

5 Jul 2022

Cell Biology

First biohybrid model of human ventricles is an important step forward for organ biofabrication

Scientists uncover how the innate immune system detects and fights HIV-1

Study offers a new understanding of the evolutionary diversification of KNL2 gene

Study finds microglia to be responsible for neuronal death in a mitochondrial disease animal model

Commercial antibodies do not recognize immune receptor ACKR1

Disrupting genes in the yeast Pichia pastori to increase its secretory production of useful proteins

IMBA researchers uncover basic principles of early development using blastoids

Scientists identify molecules promoting plant immunity

The Life Sciences; Where are we now, and where are we going?

MIT chemists discover how changes in a shape-shifting receptor trigger cell growth

Vaccine generates antibodies that target SARS-CoV-2 spike protein regions shared among many coronaviruses

Researchers challenge centuries-old beliefs about limb regeneration

Running faster and dreaming help your left brain and right brain to communicate better

Study yields molecular clues that could lead to new treatments for rare genetic disease

Genetically engineered kidney organoids solve mystery of a rare disease

"Selfish chromosomes" explain why most human embryos die very early on, study suggests

Gene defect underlying Krabbe disease causes degeneration of neurons directly, study finds

Researchers explore how diet and feeding patterns affect intestinal microbes

Study opens up a new avenue for the development of selective drug therapies

Study identifies a molecule that boosts fat burning

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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