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New data from Novartis' ACZ885 Phase III study on SJIA

Novartis announced today new pivotal Phase III data showing 45% of children with active systemic juvenile idiopathic arthritis (SJIA) were able to substantially reduce their use of oral corticosteroids (often described as steroids) within 28 weeks of commencing treatment with ACZ885.

7 Nov 2011

MRSA co-infection increases risk of flu-related mortality among children

During the 2009 H1N1 influenza pandemic, many previously healthy children became critically ill, developing severe pneumonia and respiratory failure, sometimes fatal. The largest nationwide investigation to date of influenza in critically ill children, led by Children's Hospital Boston, found one key risk factor: Simultaneous infection with methicillin-resistant Staphylococcus aureus (MRSA) increased the risk for flu-related mortality 8-fold among previously healthy children.

7 Nov 2011

Respiratory problems in homes on the rise due to air freshners

Sales of home air fresheners and scented candles are on the rise and so are respiratory problems in homes where these products are used, according to allergists at the annual scientific meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Boston, Nov 3-8.

7 Nov 2011

Children with polyarticular JIA benefit from early and aggressive therapy

Children with juvenile arthritis who are treated early and aggressively have better outcomes, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago.

7 Nov 2011

Study finds pregnancy safe for 80% of women with lupus

Promising research led by investigators at Hospital for Special Surgery may offer hope for women with lupus who once thought that pregnancy was too risky.

7 Nov 2011

VBF, BLI hold 14th annual Port Wine Stain and Vascular Birthmarks Conference

The Vascular Birthmarks Foundation (VBF), along with the Beckman Laser Institute (BLI) and Medical Director Dr. J. Stuart Nelson, are holding the fourteenth annual Port Wine Stain and Vascular Birthmarks Conference beginning today at the University of California-Irvine.

5 Nov 2011

Supplemental dose of pneumonia vaccine recommended for age-eligible patients

In a new report from the Centers for Disease Control and Prevention, healthcare providers are being urged to administer a supplemental dose of the 13-valent pneumococcal conjugate vaccine to age-eligible patients as they come in for visits.

5 Nov 2011

Single-parent status, household income linked to increased rate of hospital readmissions of asthmatic children

Financial strain and competing priorities at home may contribute to the greater number of hospital readmissions of children with asthma from single-parent homes compared to dual-parent households, according to a new study presented at the American College of Allergy, Asthma and Immunology Annual Meeting in Boston, Nov. 3-8.

5 Nov 2011

States lack policies to curb classroom burden of asthma and severe allergies

For over 7 million children with asthma, and 13 million with food allergy or other severe allergies, going to school is a daily risk affecting how well they can – or can't – manage their diseases. Now for the fourth year, the Asthma and Allergy Foundation of America has released its annual report assessing all 50 states and the District of Columbia on their leadership and progress on school-based policies that address student asthma and allergy health in more than 100,000 elementary, middle and high schools across the U.S.

5 Nov 2011

Eat'n Park unfolds Caring for Kids Campaign to raise funds for Children's Hospital of Pittsburgh

Eat'n Park is rolling out its 33rd annual Caring for Kids Campaign to raise funds for Children's Hospital of Pittsburgh of UPMC. Beginning today and running through December 11, guests are invited to purchase a raffle ticket for the chance to win a new 2012 Ford Focus.

5 Nov 2011

Appropriate tests, treatments needed for pediatric TB

In this post on the PLoS "Speaking of Medicine" blog, Grania Brigden, the tuberculosis adviser to the Medecins Sans Frontieres Campaign for Access to Essential Medicines, writes that while "[t]his year's Global Tuberculosis Control report shows the beginning of a decline in the global tuberculosis epidemic, ... there is a stark lack of data for children," continuing, "Without a clear estimate of the magnitude of the problem it is hard to motivate governments, researchers and donors."

5 Nov 2011

Key Assets expands foster care provision in Western Australia

Key Assets is expanding its foster care provision in Western Australia with the upcoming launch of a new disability services program.

5 Nov 2011

Baxter launches NUMETA emulsion for infusion in Europe

Baxter International Inc. announced today the European launch of NUMETA (emulsion for infusion).

From Baxter International Inc. 4 Nov 2011

Whole genome sequencing can identify strains of caries-causing bacteria

Severe early childhood caries can destroy most of a child's teeth by age three, and disproportionately affects underserved populations, including American Indians and Alaskan natives. Although the link between Lactobacilli bacteria (Lb) and severe early childhood caries has been known for almost a century, progress in delineating which of 140 Lb species are responsible for the disease has remained elusive.

4 Nov 2011

New link between obesity, SDB and cognition among elementary school children

Researchers at the University of Chicago have found important new relationships between obesity, sleep-disordered breathing (SDB) and cognitive processing among elementary school children.

4 Nov 2011

Final results from Vertex KALYDECO second of two Phase 3 studies on CF

Vertex Pharmaceuticals Incorporated today announced final results from the ENVISION study, the second of two pivotal Phase 3 studies of KALYDECO, a medicine in development that targets the defective protein that causes cystic fibrosis.

4 Nov 2011

Reduced diversity of intestinal microbiota associated with increased risk of allergic disease

Oversensitivity diseases, or allergies, now affect 25 per cent of the population of Denmark. The figure has been on the increase in recent decades and now researchers at the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), University of Copenhagen, are at last able to partly explain the reasons.

3 Nov 2011

Measles virus develops a strategy of diabolic elegance

Mayo Clinic researchers have discovered why measles, perhaps the most contagious viral disease in the world, spreads so quickly. The virus emerges in the trachea of its host, provoking a cough that fills the air with particles ready to infect the next host. The findings may also help in the fight against ovarian, breast and lung cancers.

3 Nov 2011

Study reveals what causes lysosome to overflow in Batten disease

Waste management is a big issue anywhere, but at the cellular level it can be a matter of life and death. A Weizmann Institute study, published in the Journal of Cell Biology, has revealed what causes a molecular waste container in the cell to overflow in Batten disease, a rare but fatal neurodegenerative disorder that begins in childhood.

3 Nov 2011

Increasing TR2/TR4 expression can lead to higher fetal hemoglobin levels in sickle cell patients

A University of Michigan Health System laboratory study reveals a key trigger for producing normal red blood cells that could lead to a new treatment for those with sickle cell disease.

3 Nov 2011