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Study reveals two distinct types of obesity with physiological and molecular differences

A team led by Van Andel Institute scientists has identified two distinct types of obesity with physiological and molecular differences that may have lifelong consequences for health, disease and response to medication.

12 Sep 2022

Small molecule inhibitor found to be effective against SARS-CoV-2 variants

In a new study, researchers developed RK-33, a small molecule inhibitor of DDX3, and evaluated its efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

12 Sep 2022

UQ researchers receive international funding to combat melanoma in US troops

Researchers at The University of Queensland have been awarded international funding to combat an expected escalation of skin cancer cases in US troops who served in Iraq and Afghanistan.

12 Sep 2022

Patients with high-risk melanoma benefit from immunotherapy prior to surgery

Patients with high-risk melanoma who received the immunotherapy drug pembrolizumab both before and after surgery to remove cancerous tissue had a significantly lower risk of their cancer recurring than similar patients who received the drug only after surgery.

12 Sep 2022

Study shortlists potential drug repurposing candidates to treat symptoms in ASD

Can you teach an old drug new tricks? Although drug treatments for the core symptoms of autism spectrum disorder (ASD) are not currently available, could an existing drug provide a new treatment, even if it previously had no association with ASD? This was the question asked by a new study in the journal Frontiers in Pharmacology. The researchers used a computer model that encompasses proteins involved in ASD and the way they interact.

12 Sep 2022

Novel tests detect common cancer signals across over 50 types of cancer

Cancer doctors, care providers and payers need to get ready for a major shift in early cancer detection that will affect almost every stage of cancer diagnosis and treatment. New data supporting the accuracy of multi-cancer early detection (MCED) blood testing (1), presented at the ESMO Congress 2022, have major implications for future cancer care provision, said Fabrice André, ESMO 2022 Scientific Co-Chair.

12 Sep 2022

Semaglutide appears to be an effective medication for treating obesity, study says

The risk of type 2 diabetes (T2D) is more than halved by weekly injections of new obesity drug semaglutide, according to new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Stockholm, Sweden (19-23 Sept).

12 Sep 2022

Pre-existing psychological distress increases risk of long-COVID

In a recent study published in the Journal of American Medical Association (JAMA) Psychiatry, researchers investigated the association of psychological distress before coronavirus disease 2019 (COVID-19) with the risk of post-acute sequelae of COVID-19 (PASC).

12 Sep 2022

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

A novel treatment strategy with personalized cell therapy significantly improves progression-free survival compared to standard immunotherapy in patients with advanced melanoma, according to ground-breaking results reported at the ESMO Congress 2022 from the phase 3 M14TIL trial.

12 Sep 2022

Pollutant particles in the air trigger lung cancer in non-smokers

A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies, according to late-breaking data [to be] reported at the ESMO Congress 2022 by scientists of the Francis Crick Institute and University College London, funded by Cancer Research UK. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year.

12 Sep 2022

Brain injury a common consequence of both COVID-19 and influenza

In a recent study published in the journal Brain, researchers reported that brain injury is common in coronavirus disease 2019 (COVID-19) and influenza.

12 Sep 2022

Study reveals gut-brain circuits drive cravings for fatty foods

In a recent study published in the journal Nature, researchers explored the neural basis for fat preference and identified receptors and neuronal elements mediating its development.

11 Sep 2022

Heart risks associated with artificial sweeteners

In a recent study published in the British Medical Journal, researchers investigated the relationship between the intake of artificial sweeteners and the risk of all cardiovascular diseases (CVDs), including cardiometabolic disorders.

11 Sep 2022

Parental BMI and early childhood weight gain predicts increased girth at 5 years

A new study reports a correlation between parental weight and rapid childhood weight gain with increased abdominal fat at five years of age.

11 Sep 2022

Long COVID linked to persistence of SARS-CoV-2 spike protein in blood

A new study reports SARS-CoV-2 spike antigen and cytokine levels in a sample of infected individuals, of which a subset had long COVID.

11 Sep 2022

Survey: 'Healthy tan' and other myths about sun safety are alive in Europe, other countries

8 in 10 Europeans believe tans are attractive with almost as many (73%) saying tans are healthy, according to a new study presented today at the 31st European Academy of Dermatology and Venereology (EADV) Congress.

9 Sep 2022

New research project investigates molecular mechanisms underlying NeuroCOVID

Infections with the coronavirus SARS-CoV-2 can trigger both temporary and long-term neurological and neuropsychiatric symptoms, severely impacting patients and the wider society.

9 Sep 2022

Residential exposure to petroleum refining linked to stroke rates across the Southern United States

A new study has revealed that exposure to pollutants from petroleum refineries has a strong link to stroke rates across the Southern United States. The results were published today in IOP Publishing's journal Environmental Research Letters.

9 Sep 2022

Kessler Foundation receives grant to continue the long-running "MS Fellowship in Neuropsychological Rehabilitation" program

John DeLuca, PhD, senior vice president of research and training at Kessler Foundation, received a five-year, $468,019 grant from the National Multiple Sclerosis Society to continue the long-running "MS Fellowship in Neuropsychological Rehabilitation" program.

9 Sep 2022

Study: Racial, ethnic minorities in L.A. County more likely to live as far from cardiac rehabilitation facility

Racial and ethnic minorities in Los Angeles County are more likely to live as far as or farther than five miles from a cardiac rehabilitation facility, according to a new study by investigators at the Smidt Heart Institute at Cedars-Sinai.

9 Sep 2022