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MOO can alleviate depression via increasing 5-HTP in the gut microbiota, study reveals

Announcing a new article publication from Acta Pharmaceutica Sinica B. Morinda officinalis oligosaccharides(MOO) is an oral drug approved in China for the treatment of depression in China.

5 Sep 2022

Targeting Gαq/11 may be an efficient therapeutic strategy against uveal melanoma

Announcing a new article publication from Acta Pharmaceutica Sinica B. Constitutively activated G proteins caused by specific mutations mediate the development of multiple malignancies.

5 Sep 2022

Recent advances in nano-based therapeutic strategies for the treatment of infectious lung diseases

Announcing a new publication for Acta Materia Medica journal. Infectious lung diseases are inflammatory diseases of the lungs caused by infectious agents such as bacteria, viruses or fungi.

5 Sep 2022

Bronchodilators do little to help people without COPD but have smoking-related respiratory symptoms

Researchers supported by the National Institutes of Health have found that dual bronchodilators - long-lasting inhalers that relax the airways and make it easier to breathe - do little to help people who do not have chronic obstructive pulmonary disease (COPD), but who do have respiratory symptoms and a history of smoking.

5 Sep 2022

Researchers secure $20.5 million NIH grant to beat Alzheimer's disease and related dementias

A team of researchers at the University of Kentucky's Sanders-Brown Center on Aging has been awarded a $20.5 million grant from the National Institute on Aging of the National Institutes of Health.

2 Sep 2022

Cooler ambient temperatures in the tropics increase risk of heart attacks

Scientists have long known that temperature changes impact the incidence of heart attacks. However, most of the research done so far has been in temperate climates, where temperatures range widely.

2 Sep 2022

Case study shows potential to develop myocarditis following monkeypox infection

A 31-year-old male with confirmed monkeypox infection developed acute myocarditis approximately one week following the onset of monkeypox symptoms, according to a case study published today in JACC: Case Reports.

2 Sep 2022

Clinical trial shows efficacy and safety of belimumab in East Asian adults with lupus nephritis

This prespecified subgroup analysis of East Asian adults who participated in a phase 3 clinical trial of belimumab added to standard therapy vs. placebo added to standard therapy for lupus nephritis shows earlier and more sustained improvement in kidney outcomes with the addition of belimumab.

2 Sep 2022

Circadian rhythm disruption is shared by a broad range of mental illnesses, study finds

Anxiety, autism, schizophrenia and Tourette syndrome each have their own distinguishing characteristics, but one factor bridging these and most other mental disorders is circadian rhythm disruption, according to a team of neuroscience, pharmaceutical sciences and computer science researchers at the University of California, Irvine.

2 Sep 2022

Depletion of reactive astrocytes regresses glioblastoma

A groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cancer. The researchers achieved the outcome using a method they developed based on their discovery of two critical mechanisms in the brain that support tumor growth and survival: one protects cancer cells from the immune system, while the other supplies the energy required for rapid tumor growth. The work found that both mechanisms are controlled by brain cells called astrocytes, and in their absence, the tumor cells die and are eliminated.

2 Sep 2022

Researchers develop novel therapeutic strategy to treat Huntington's disease

Through an international joint research effort involving ProQR Therapeutics of the Netherlands, Université Grenoble Alpes of France, and KTH Royal Institute of Technology of Sweden, Professor Ji-Soon Song's research team in the Department of Biological Sciences and KAIST Institute for BioCentury of KAIST, established a noble strategy to treat Huntington's disease. The new works showed that the protein converted from disease form to its disease-free form maintains its original function, providing new roadblocks to approach Huntington's disease.

2 Sep 2022

GnRH therapy could improve cognitive deficits in men with Down syndrome

Gonadotropin-releasing hormone (GnRH) therapy improves cognitive function in Down syndrome (DS) mouse models and male patients with DS, according to a new study.

1 Sep 2022

Researchers identify how some cancer cells cheat treatment-induced cell death

Scientists at St. Jude Children's Research Hospital have identified how some cancer cells cheat treatment-induced cell death.

1 Sep 2022

Gene variants associated with blood type may contribute to risk of early stroke

Gene variants associated with a person's blood type may be linked to their risk of early stroke, according to a new meta-analysis published in the August 31, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

1 Sep 2022

Type 2 diabetes remission achieved more effectively with bariatric surgery than lifestyle changes

Remission of type 2 diabetes is achieved more effectively and has longer-lasting results with bariatric surgery than through medications and lifestyle changes.

1 Sep 2022

Early therapeutic interventions may be effective in treating Fragile X Syndrome

A new study suggests that therapeutic interventions to treat neurodevelopmental disorders may be more effective if done during the early stages of brain development.

1 Sep 2022

Study suggests strategies to bolster the administration of clot-busting drugs

Venous thromboembolism (VTE) is a potentially deadly condition in which a blood clot (known as a deep vein thrombosis [DVT]) forms in the deep veins of the leg, groin or arm and may dislodge.

1 Sep 2022

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Researchers at Sanford Burnham Prebys, led by Ze'ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth.

1 Sep 2022

Simple blood test may identify patients at high risk of neurotoxic complications after CAR-T cell therapy

Cell-based immunotherapy called CAR-T cell therapy has revolutionized the treatment of several cancers.

1 Sep 2022

Study shows encouraging therapeutic options for patients with relapsed multiple myeloma

Mount Sinai researchers have published results that show encouraging therapeutic options for patients with the blood cancer multiple myeloma after first-line treatment with bispecific antibodies fails.

1 Sep 2022

Medical Condition News

MOO can alleviate depression via increasing 5-HTP in the gut microbiota, study reveals

Targeting Gαq/11 may be an efficient therapeutic strategy against uveal melanoma

Recent advances in nano-based therapeutic strategies for the treatment of infectious lung diseases

Bronchodilators do little to help people without COPD but have smoking-related respiratory symptoms

Researchers secure $20.5 million NIH grant to beat Alzheimer's disease and related dementias

Cooler ambient temperatures in the tropics increase risk of heart attacks

Case study shows potential to develop myocarditis following monkeypox infection

Clinical trial shows efficacy and safety of belimumab in East Asian adults with lupus nephritis

Circadian rhythm disruption is shared by a broad range of mental illnesses, study finds

Depletion of reactive astrocytes regresses glioblastoma

Researchers develop novel therapeutic strategy to treat Huntington's disease

GnRH therapy could improve cognitive deficits in men with Down syndrome

Researchers identify how some cancer cells cheat treatment-induced cell death

Gene variants associated with blood type may contribute to risk of early stroke

Type 2 diabetes remission achieved more effectively with bariatric surgery than lifestyle changes

Early therapeutic interventions may be effective in treating Fragile X Syndrome

Study suggests strategies to bolster the administration of clot-busting drugs

Inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth

Simple blood test may identify patients at high risk of neurotoxic complications after CAR-T cell therapy

Study shows encouraging therapeutic options for patients with relapsed multiple myeloma

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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