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Study shows long-term safety and biologic activity of golodirsen in DMD patients

This first-in-human study of golodirsen showed its long-term safety and biologic activity in patients with Duchenne Muscular Dystrophy (DMD). The approved exon-skipping therapy is designed to enable the production of functional dystrophin proteins, as described in the peer-reviewed journal Nucleic Acid Therapeutics.

1 Dec 2021

Scientists discover low amounts of cholesterol in tumor-associated macrophages

Significant changes in lipid metabolism are known to occur in cells associated with non-small-cell lung carcinoma – the most common form of lung cancer.

30 Nov 2021

Research offers new insight on the origins of stuttering

About one in 20 people go through a period of stuttering during childhood. Until the latter half of the 20th century, stuttering was believed to be a psychological problem stemming from lack of effort or from trauma.

30 Nov 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

First standardized Russian-language test developed for aphasia-related disorders

Researchers from the HSE University Centre for Language and Brain have created and standardized a new test battery for diagnosing language disorders in people with brain damage.

30 Nov 2021

New safe, painless diagnostic tool for detecting breast cancer

Mammograms are a safe, effective way to detect the presence of breast cancer in women. But doctors recommend most females should start getting mammograms after the age of 40 in part because the procedure involves small doses of ionizing radiation.

30 Nov 2021

First-of-its-kind PET imaging-based tool developed to detect liver inflammation in NAFLD patients

A UC Davis Health team has developed a first-of-its-kind positron emission tomography (PET) scan imaging-based tool to detect liver inflammation in patients affected with non-alcoholic fatty liver disease.

30 Nov 2021

Prior infection with SARS-CoV-2 continues to provide protection from reinfection

Researchers from the University of Michigan investigated the correlation between SARS-CoV-2 infection and the severity of reinfections.

30 Nov 2021

Potentially neurotoxic SARS-CoV-2 protein fragments

Researchers investigate potentially amyloidogenic peptide fragments that could be associated with the neurological symptoms of COVID-19 and long-COVID.

30 Nov 2021

Researchers dissect the shared genetic architecture of suicide attempts and psychiatric disorders

In the largest genetic study of suicide attempts to date, researchers have identified a region of the genome on chromosome 7 containing DNA variations that increase the risk that a person will attempt suicide.

30 Nov 2021

Study finds early stages of sarcopenia could be counteracted with timely interventions

Weakening muscles are a natural part of the ageing process, but for some people with a condition called sarcopenia the decline is abnormally fast.

30 Nov 2021

Prevalence of type 2 diabetes is elevated in people with a psychiatric disorder

A new study published in Diabetologia (the journal of the European Association for the Study of Diabetes (EASD)) finds that the prevalence of type 2 diabetes (T2D) is elevated in people with a psychiatric disorder compared with the general population.

30 Nov 2021

Industrially processed foods increase the risk of a second heart attack or a fatal stroke

Ultra-processed foods are a major public health concern for their potential adverse effects on health. Now a study by the Department of Epidemiology and Prevention of the I.R.C.C.S. Neuromed in Pozzilli (Italy) explores the health effects of a large dietary share of ultra-processed food on people already suffering from cardiovascular diseases.

30 Nov 2021

Anti-SARS-CoV-2 antibodies suggested to be safe to use in pregnancy

Pregnant patients with mild to moderate COVID-19 were treated with MAb and reported no adverse effects.

30 Nov 2021

Study uncovers new mechanism to explain how obesity jeopardizes the functions of skeletal muscle

A decline in metabolism and endurance of skeletal muscle is commonly observed in obese patients, but the underlying mechanism is not well-understood.

30 Nov 2021

$Phase I trial evaluates safety, efficacy of astatine for use in alpha therapy for refractory thyroid cancer patients$

Phase I trial evaluates safety, efficacy of astatine for use in alpha therapy for refractory thyroid cancer patients

A research team from the Graduate School of Medicine at Osaka University has started an investigator-initiated clinical trial of sodium astatine ([211At]NaAt) injection for refractory differentiated thyroid cancer patients.

29 Nov 2021

Researchers develop novel system for rapid and non-invasive detection of skin cholesterol

Cardiovascular diseases (CVDs) are the leading cause of death globally. Monitoring of lipid in patients with coronary heart disease (CHD) is important for decreasing the incidence of cardiovascular events.

29 Nov 2021

Clinical drug research for the treatment of CNS and neurological disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

29 Nov 2021

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

Funded by a Specialized Program of Research Excellence award from the National Cancer Institute (NCI), the Kidney Cancer Program at UT Southwestern's Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse catalog of kidney cancer tumor models to date.

29 Nov 2021

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Researchers study human single nucleotide variants (SNVs) using machine learning to identify amino acid changes that alter kinase-bound sequence motifs.

29 Nov 2021

Medical Condition News

Study shows long-term safety and biologic activity of golodirsen in DMD patients

Scientists discover low amounts of cholesterol in tumor-associated macrophages

Research offers new insight on the origins of stuttering

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

First standardized Russian-language test developed for aphasia-related disorders

New safe, painless diagnostic tool for detecting breast cancer

First-of-its-kind PET imaging-based tool developed to detect liver inflammation in NAFLD patients

Prior infection with SARS-CoV-2 continues to provide protection from reinfection

Potentially neurotoxic SARS-CoV-2 protein fragments

Researchers dissect the shared genetic architecture of suicide attempts and psychiatric disorders

Study finds early stages of sarcopenia could be counteracted with timely interventions

Prevalence of type 2 diabetes is elevated in people with a psychiatric disorder

Industrially processed foods increase the risk of a second heart attack or a fatal stroke

Anti-SARS-CoV-2 antibodies suggested to be safe to use in pregnancy

Study uncovers new mechanism to explain how obesity jeopardizes the functions of skeletal muscle

Phase I trial evaluates safety, efficacy of astatine for use in alpha therapy for refractory thyroid cancer patients

Researchers develop novel system for rapid and non-invasive detection of skin cholesterol

Clinical drug research for the treatment of CNS and neurological disorders

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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