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Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Researchers at Johns Hopkins Medicine have found that a drug first developed to treat Alzheimer's disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function — without changes in food intake or daily activity.

7 Oct 2021

Accumulation of amyloid beta and reduction of serotonin may trigger late-life depression

Looking for ways to image the human brain for the earliest signs of aging and cognitive decline, Johns Hopkins Medicine researchers recently identified a pattern that links the accumulation of amyloid beta (Aβ) proteins (associated with cognitive decline later in life) with a reduction of serotonin, the brain chemical that improves mood.

7 Oct 2021

Oral health linked to COVID-19 severity in patients with cardiac diseases

The correlation between poor oral health and COVID-19 severity, as well as the correlation between oral health and delayed recovery, demonstrates a potential need to consider oral health an additional risk factor for cardiac patients who may contract COVID-19.

7 Oct 2021

$'Fractionated' radiation therapy for spinal tumors helps prevent vertebral compression fractures$

'Fractionated' radiation therapy for spinal tumors helps prevent vertebral compression fractures

In an animal study published Oct. 1, 2021, in the International Journal of Radiation Oncology, Biology and Physics, Johns Hopkins Medicine researchers have provided evidence that treating spinal tumors with "fractionated" radiation therapy — doses given in a series of sessions rather than a single treatment — helps prevent vertebral compression fractures.

7 Oct 2021

Deadly subtype of T-cell lymphoma harbors unique mutations

An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in a specific protein signaling pathway, according to a study published in the journal Blood.

7 Oct 2021

New technology shows great promise for early diagnosis of Alzheimer’s disease

A technology developed by scientists at Lawrence Berkeley National Laboratory (Berkeley Lab) shows great promise for diagnosing Alzheimer's disease before symptoms arise, potentially changing the course of research and treatment for this condition, which affects millions of people worldwide and is estimated to be the sixth leading cause of death in the United States.

7 Oct 2021

Australian researchers hope to switch on sight with new gene therapy

Australian researchers are developing a new gene therapy which they hope will ‘switch on sight’ by regenerating light-sensing photoreceptor cells in the retina at the back of the eye.

7 Oct 2021

Liquid biopsy enables early, accurate identification of breast cancer patients with poor prognosis

Liquid biopsy can help to identify breast cancer patients with a poor prognosis earlier and more accurately than before, a new study from the University of Eastern Finland and Kuopio University Hospital shows.

7 Oct 2021

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Pairing a newly developed gel with immunotherapy that was delivered to post-surgical mouse brains with glioblastoma, a highly malignant and deadly cancer, improved the immunotherapy's effectiveness, report researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and colleagues. The findings appeared on Oct. 6, 2021, in Science Advances.

7 Oct 2021

Protecting the ozone layer could prevent cancer cases and other diseases in the U.S

An international agreement to protect the ozone layer is expected to prevent 443 million cases of skin cancer and 63 million cataract cases for people born in the United States through the end of this century, according to new research.

7 Oct 2021

Large study of COVID vaccine side effects in Sweden

Recently, researchers from Sweden reported population-based, age- and sex-specific background incidence rates of conditions that represent potential COVID-19 vaccine adverse events of special interest (AESI) in the general Swedish population with the help of registered data. This study is published on the medRxiv* preprint server.

6 Oct 2021

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

A new study published on the medRxiv* preprint server focused on a patient with a persistent symptomatic viral infection for over a year. Researchers amplified sub-genomic transcripts for the E gene (sgE) using nasopharyngeal samples of the patient infected with SARS-CoV-2 over the course of 335 days.

6 Oct 2021

Racial disparities in lung cancer survival rates can be mitigated by providing equal treatment access

Although Black lung cancer patients are more likely to die from their disease than white patients, they have better outcomes than whites when treated with immunotherapies that are now considered the best standard of care.

6 Oct 2021

Pancreatic cancer clinical trials exclude Black patients based on wide range of eligibility criteria

A simulated pancreatic cancer clinical trial screening process showed that Black patients were significantly more likely than white patients to be excluded from clinical trials for a wide range of eligibility criteria, according to results presented at the virtual 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held October 6-8, 2021.

6 Oct 2021

Pilot program tailored for trans men and nonbinary people encourages cervical screening

A pilot program that provided transgender men and nonbinary people with cervical cancer screening tailored to their biological needs and personal preferences was well-received and could provide a model for similar programs, according to results presented at the virtual 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held October 6-8, 2021.

6 Oct 2021

Chinese and Laotian Americans more likely to be diagnosed with nasopharyngeal cancer

Chinese Americans and Laotian Americans were over 10 and 14 times more likely to be diagnosed with nasopharyngeal cancer, respectively, than non-Hispanic white Americans, with incidence rates surpassing other Asian American subgroups, according to results presented at the virtual 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held October 6-8, 2021.

6 Oct 2021

Elevated allostatic load may impact treatment completion and breast cancer survival outcomes

Elevated allostatic load was associated with a lower likelihood of completing chemotherapy and a lower overall survival rate in patients with lymph node-positive or high-risk lymph node-negative HER2-negative breast cancer, according to results presented at the 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held online October 6-8, 2021.

6 Oct 2021

Does vaccination prevent long COVID?

In a recent study, researchers evaluate the effect of COVID-19 vaccination on a large ongoing prospective cohort of patients with long COVID.

6 Oct 2021

Black NSCLC patients receiving immunotherapy have lower risk of death than white counterparts

Non-Hispanic Black patients with non-small cell lung cancer (NSCLC) who were treated with immunotherapy had a lower risk of death than their non-Hispanic white counterparts treated with immunotherapy, according to results presented at the virtual 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held October 6-8, 2021.

6 Oct 2021

New digital game could help people over 50s to fight against Alzheimer's disease and dementia

UQ Healthy Living is helping over 50s in the fight against Alzheimer's disease and dementia, with a new digital game designed to train both the body and the brain.

6 Oct 2021

Medical Condition News

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Accumulation of amyloid beta and reduction of serotonin may trigger late-life depression

Oral health linked to COVID-19 severity in patients with cardiac diseases

'Fractionated' radiation therapy for spinal tumors helps prevent vertebral compression fractures

Deadly subtype of T-cell lymphoma harbors unique mutations

New technology shows great promise for early diagnosis of Alzheimer’s disease

Australian researchers hope to switch on sight with new gene therapy

Liquid biopsy enables early, accurate identification of breast cancer patients with poor prognosis

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Protecting the ozone layer could prevent cancer cases and other diseases in the U.S

Large study of COVID vaccine side effects in Sweden

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

Racial disparities in lung cancer survival rates can be mitigated by providing equal treatment access

Pancreatic cancer clinical trials exclude Black patients based on wide range of eligibility criteria

Pilot program tailored for trans men and nonbinary people encourages cervical screening

Chinese and Laotian Americans more likely to be diagnosed with nasopharyngeal cancer

Elevated allostatic load may impact treatment completion and breast cancer survival outcomes

Does vaccination prevent long COVID?

Black NSCLC patients receiving immunotherapy have lower risk of death than white counterparts

New digital game could help people over 50s to fight against Alzheimer's disease and dementia

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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