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Attenuated virulence and protective immunity in SARS-CoV-2 with a mutation in the S1/S2 cleavage site

A new study published in mBio investigates the impact of the furin cleavage site on viral growth and pathogenesis.

31 Aug 2021

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

A new study published in mBio discusses the microevolution of SARS-CoV-2.

31 Aug 2021

New research has implications for developing cancer therapies targeting mutant p53 protein

The tumor suppressor protein p53 is mutated in more than half of all human cancers. Several drugs that potentially can restore mutant p53 to its normal cancer-killing function are in clinical investigation.

31 Aug 2021

Shorter survival of multiple myeloma subgroup linked to worse kidney damage

Nearly 20% of patients with multiple myeloma have a form in which they make extreme quantities of one component of the abnormal antibody they are producing, and these so-called "free monoclonal light chains" pile up and damage the kidneys, investigators say.

31 Aug 2021

A single glass of wine can raise the drinker’s risk for atrial fibrillation

A single glass of wine can quickly – significantly – raise the drinker's risk for atrial fibrillation, according to new research by UC San Francisco.

31 Aug 2021

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

Octapharma USA today announced the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development (OOPD) has awarded seven years of marketing exclusivity for Octagam® 10% [Immune Globulin Intravenous (Human)], the first and only intravenous immunoglobulin (IVIg) to be indicated for the treatment of adult dermatomyositis (DM).

31 Aug 2021

AI approach helps identify heart failure patients who will benefit from beta-blocker therapy

Researchers at the University of Birmingham have developed a new way to identify patients with heart failure who will benefit from treatment with beta-blockers.

31 Aug 2021

New strategy combining heart failure with depression treatment improves patients' clinical outcomes

A telephone-delivered nursing care strategy that combined heart failure care management with depression treatment improved patients' clinical outcomes, discovered clinicians from the University of Pittsburgh.

31 Aug 2021

Black patients who receive kidneys from Asian donors have higher risk of kidney graft failure

Black transplant recipients and patients who received kidneys from Asian donors had a significantly higher risk of kidney graft failure within seven years, according to a new study presented at the European Society for Organ Transplantation (ESOT) Congress 2021.

31 Aug 2021

COVID-19 vaccine elicits antibody responses in nearly 9 out of 10 people taking immunosuppressants

COVID-19 vaccination elicited antibody responses in nearly nine out of 10 people with weakened immune systems, although their responses were only about one-third as strong as those mounted by healthy people, according to a study by researchers at Washington University School of Medicine in St. Louis.

30 Aug 2021

Genetic tests can provide a better picture of cardiovascular disease risk than blood tests

Determining an individual's blood group based on genetic tests instead of merely traditional blood tests can provide a better picture of the risk of cardiovascular diseases.

30 Aug 2021

Low-sodium alternative for salt lowers stroke risk

Replacing salt with a low-sodium alternative lowers the risk of stroke in people with high blood pressure or prior stroke, according to late breaking research presented in a Hot Line session today at ESC Congress 2021 and published in the New England Journal of Medicine.

30 Aug 2021

Computational study identifies human proteins structurally similar to SARS-CoV-2 proteins

A new study published in Scientific Reports identifies the human proteins that share structural similarities with the SARS-CoV-2 proteins.

30 Aug 2021

Gitelman syndrome more common in Japanese population than previously reported

Clinical Fellow KONDO Atsushi and Professor NOZU Kandai et al. of Kobe University's Graduate School of Medicine have estimated the prevalence of Gitelman syndrome across different ethnicities using a genome database.

30 Aug 2021

Researchers urge neurologists to actively encourage vaccinations for Parkinson's patients

Patients with Parkinson's disease (PD) are at higher risk for vaccine-preventable respiratory illnesses. However, patients with advanced PD may have less access to vaccinations according to a new study published in the Journal of Parkinson's Disease.

30 Aug 2021

Influenza vaccination should become a part of standard hospital care after myocardial infarction

Influenza vaccination reduces the risk of all-cause death, myocardial infarction, or stent thrombosis at 12 months in hospitalized patients with myocardial infarction or high-risk coronary disease, according to late breaking research presented in a Hot Line session today at ESC Congress 2021.

30 Aug 2021

How early interferon curbs SARS-CoV-2 infection

A new study available in the Journal of Experimental Medicine focuses on the importance of interferon in SARS-CoV-2 infection.

30 Aug 2021

More than 80% of hypertension cases now found in poorer countries

More than half a billion people worldwide live with undetected, untreated hypertension, even as the disease burden shifts from rich nations to poor countries with limited resources to detect and manage the condition.

30 Aug 2021

UH associate professor receives $2.5 million to explore how arterial hardening starts within cells

In diseases such as hypertension, aging, atherosclerosis, diabetes and chronic kidney disease, arterial calcification and stiffening of the elastic layer of the arterial wall are almost always present.

30 Aug 2021

Intensive blood-pressure control benefits older hypertensive patients

Aggressive blood pressure treatment in older hypertensive patients lowers the incidence of cardiovascular events compared to standard therapy, without increasing adverse outcomes. That's the finding of late breaking research presented in a Hot Line session today at ESC Congress 2021.

30 Aug 2021

Medical Condition News

Attenuated virulence and protective immunity in SARS-CoV-2 with a mutation in the S1/S2 cleavage site

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

New research has implications for developing cancer therapies targeting mutant p53 protein

Shorter survival of multiple myeloma subgroup linked to worse kidney damage

A single glass of wine can raise the drinker’s risk for atrial fibrillation

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

AI approach helps identify heart failure patients who will benefit from beta-blocker therapy

New strategy combining heart failure with depression treatment improves patients' clinical outcomes

Black patients who receive kidneys from Asian donors have higher risk of kidney graft failure

COVID-19 vaccine elicits antibody responses in nearly 9 out of 10 people taking immunosuppressants

Genetic tests can provide a better picture of cardiovascular disease risk than blood tests

Low-sodium alternative for salt lowers stroke risk

Computational study identifies human proteins structurally similar to SARS-CoV-2 proteins

Gitelman syndrome more common in Japanese population than previously reported

Researchers urge neurologists to actively encourage vaccinations for Parkinson's patients

Influenza vaccination should become a part of standard hospital care after myocardial infarction

How early interferon curbs SARS-CoV-2 infection

More than 80% of hypertension cases now found in poorer countries

UH associate professor receives $2.5 million to explore how arterial hardening starts within cells

Intensive blood-pressure control benefits older hypertensive patients

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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