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Experimental drug and immunotherapy combination shows promise in bladder cancer study

A new study in mice found that adding the experimental drug entinostat to an immunotherapy-like treatment substantially boosted cancer remission.

16 Aug 2021

Wildfire smoke affects 3 million asthmatics and more than half of the U.S. states, research reveals

An estimated 3 million asthmatics and over half of the states in the United States are being affected by particulates that are blowing over them from fires in Canada and the western U.S., according to new research at The University of Alabama in Huntsville, a part of the University of Alabama System.

16 Aug 2021

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Combining a histone deacetylase inhibitor drug with immunotherapy agents is safe, and may benefit some patients with advanced cancers that have not responded to traditional therapy, according to results of a phase 1 clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center, Bloomberg~Kimmel Institute for Cancer Immunotherapy and several other centers including University of Pittsburgh Cancer Institute, Yale Cancer Center and City of Hope in Los Angeles, which participated in study enrollment, and the University of Southern California and University College Cork in Ireland, which collaborated on analysis of the data.

16 Aug 2021

Single two-hour session of pain management skills could offer as much benefit as longer-course of CBT

A single two-hour session of a pain management skills class could offer as much benefit as eight sessions of cognitive behavioral therapy (CBT) for patients experiencing chronic low-back pain (CLBP), suggests a study published in JAMA Network Open.

16 Aug 2021

Research reveals increased risk of heart problems associated with night shift work

People who work night shifts are at increased risk of developing an irregular and often abnormally fast heart rhythm called atrial fibrillation (AF), according to research published in the European Heart Journal.

16 Aug 2021

Study reports the prevalence of different types of shock in COVID-19 patients

A new database analysis of critically ill patients with pneumonia related to COVID-19, published in the American Journal of Cardiology and conducted at Hackensack Meridian Hackensack University Medical Center (HUMC), is the first study to report the prevalence of different types of shock in patients with COVID-19.

16 Aug 2021

Clinical discussions on diet-associated NAFLD and COVID-19 mortality risk among PPI users

The August issue of The American Journal of Gastroenterology includes clinical discussions of diet-associated NAFLD risk and increased risk of mortality from COVID-19 among PPI users.

16 Aug 2021

Excluding race factor from kidney function estimates may affect clinical outcomes for Black cancer patients

Removing race as a factor in a kidney function-estimating equation used to guide cancer treatment dosing and eligibility may decrease the proportion of Black patients recommended to receive full doses of anticancer drugs.

16 Aug 2021

SARS-CoV-2 Spike may trigger production of antibodies that cross-react with human thrombopoietin to induce thrombocytopenia

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infected individuals often suffer from thrombocytopenia, a condition associated with low platelet counts. The cytokine thrombopoietin regulates platelet count. Previous studies have reported that thrombocytopenia can increase the coronavirus disease 2019 (COVID-19) mortality rate by about five times.

16 Aug 2021

Role of neutrophil-epithelial interactions in SARS-CoV-2 infection

Researchers discuss the relationship between airway neutrophils and SARS-CoV-2 infection to determine the impact that neutrophils have on COVID-19.

15 Aug 2021

Utah warns of Delta variant eroding COVID vaccine effectiveness

A recent study finds a reduction in vaccine effectiveness against COVID-19 in Utah corresponding to the spread of the Delta variant in the region.

15 Aug 2021

Study helps to clarify the post-clinical trial needs of cancer patients

Cancer clinical trials (CCTs) provide patients an opportunity to receive experimental drugs, tests, and/or procedures that can lead to remissions. For some, a CCT may seem like their only option. Yet little is known about the experiences of patient participants who withdraw from CCTs.

14 Aug 2021

Removal of race from kidney function estimates may negatively impact care for Black cancer patients

An accurate assessment of a patient's kidney function is critical for determining eligibility for anticancer treatments.

14 Aug 2021

Study illuminates the link between cholesterol and Alzheimer's-associated toxic protein clumps

A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer's-associated protein amyloid beta (Aβ) in the brain is tightly regulated by cholesterol.

13 Aug 2021

Study finds durable responses to immunotherapy in rare angiosarcomas

In a small study of 16 patients with the rare cancer angiosarcoma, tumors in four patients partially or completely responded to treatment with a combination of the immunotherapy drugs ipilimumab and nivolumab.

13 Aug 2021

Specific leukemia gene mutations exert divergent effects on DNA repair and sensitivity to PARP Inhibitors

In a recent study published in Cancer Research, researchers from Fels Cancer Institute for Personalized Medicine at the Lewis Katz School of Medicine at Temple University and Fox Chase Cancer Center identified specific leukemia gene mutations and the mechanisms by which they regulate DNA repair and respond to PARP inhibitors.

13 Aug 2021

Scientists develop AI-based model to diagnose cardiovascular diseases and diabetes

South Ural State University (SUSU) scientists together with colleagues from Spain, France, and Egypt have developed a model for more effective diagnosis of cardiovascular diseases and diabetes using artificial intelligence and Internet of Things technology.

13 Aug 2021

Study finds comparatively less marijuana use in cancer patients than the general public

Last month, three states – Virginia, South Dakota, and Connecticut – joined the ranks of more than a dozen others that have legalized marijuana – also known as cannabis – for recreational use. Yet, despite these changing laws and growing social acceptance of the drug, a new study finds that use is still lower among cancer patients.

13 Aug 2021

Study highlights the significance of screening for pre-cancerous Barrett’s esophagus

Abnormal cells that go on develop into oesophageal cancer – cancer that affects the tube connecting the mouth and stomach – start life as cells of the stomach, according to scientists at the University of Cambridge.

13 Aug 2021

Study finds cognitive safety of ketamine and esketamine for patients with treatment-resistant depression

Used for the treatment of depression that does not respond to standard antidepressant medications, the anesthesia drug ketamine – and the related drug esketamine, recently approved for depression treatment – has no important adverse effects on memory, attention, or other cognitive processes, concludes a systematic review of medical research in the September/October issue of Harvard Review of Psychiatry.

12 Aug 2021

Medical Condition News

Experimental drug and immunotherapy combination shows promise in bladder cancer study

Wildfire smoke affects 3 million asthmatics and more than half of the U.S. states, research reveals

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Single two-hour session of pain management skills could offer as much benefit as longer-course of CBT

Research reveals increased risk of heart problems associated with night shift work

Study reports the prevalence of different types of shock in COVID-19 patients

Clinical discussions on diet-associated NAFLD and COVID-19 mortality risk among PPI users

Excluding race factor from kidney function estimates may affect clinical outcomes for Black cancer patients

SARS-CoV-2 Spike may trigger production of antibodies that cross-react with human thrombopoietin to induce thrombocytopenia

Role of neutrophil-epithelial interactions in SARS-CoV-2 infection

Utah warns of Delta variant eroding COVID vaccine effectiveness

Study helps to clarify the post-clinical trial needs of cancer patients

Removal of race from kidney function estimates may negatively impact care for Black cancer patients

Study illuminates the link between cholesterol and Alzheimer's-associated toxic protein clumps

Study finds durable responses to immunotherapy in rare angiosarcomas

Specific leukemia gene mutations exert divergent effects on DNA repair and sensitivity to PARP Inhibitors

Scientists develop AI-based model to diagnose cardiovascular diseases and diabetes

Study finds comparatively less marijuana use in cancer patients than the general public

Study highlights the significance of screening for pre-cancerous Barrett’s esophagus

Study finds cognitive safety of ketamine and esketamine for patients with treatment-resistant depression

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