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Adding immune oncology drug to chemotherapy improves response in subset of breast cancer patients

In a new study by researchers at Yale Cancer Center, combining the immunotherapy drug durvalumab and PARP-inhibitor olaparib with chemotherapy improved response to treatment for women with high-risk, HER2-negative breast cancer, including a subset of estrogen receptor positive cancers.

18 Jun 2021

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails.

18 Jun 2021

Alarming COVID study indicates long-term loss of gray matter and other brain tissue

In a research paper recently uploaded to the preprint server medRxiv* by Prof. Gwenaëlle Douaud et al. (June 15th, 2021), participants that had taken part in a brain study prior to the onset of the COVID-19 pandemic were invited back for a series of follow-up tests, revealing significant losses of grey matter surrounding the olfactory and gustatory system in those that had been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Jun 2021

Study shows how a specific gut bacterium influences infant immune system

Research published today in the journal Cell is the first to establish how a specific gut bacterium, activated Bifidobacterium infantis EVC001 (B. infantis), influences immune system development in infants, and could thereby reduce the risk of allergic and autoimmune conditions later in life.

18 Jun 2021

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

Case Western Reserve University researchers studying prions - misfolded proteins that cause lethal incurable diseases - have identified for the first time surface features of human prions responsible for their replication in the brain.

18 Jun 2021

Foresight Diagnostics to demonstrate utility of PhasED-Seq technology at ICML meeting

Foresight Diagnostics, the emerging leader in blood-based lymphoma disease monitoring, announced today that clinical performance of its minimal residual disease (MRD) detection platform in diffuse large B-cell lymphoma (DLBCL) will be presented at the 16th International Conference on Malignant Lymphoma (ICML) on June 18-22, 2021.

18 Jun 2021

Proven treatment for psychosis has been recognized as standard of care

Most people with a serious mental illness like schizophrenia will not obtain adequate care. Many end up in correctional facilities on medication or become homeless.

18 Jun 2021

New details on transport protein could help develop drugs for neurological diseases

New details on the structure and function of a transport protein could help researchers develop drugs for neurological diseases that are better able to cross the blood-brain barrier.

18 Jun 2021

APOE ɛ4 carriers with midlife depressive symptoms may be at higher risk of tau accumulation

Middle-aged people with depressive symptoms who carry a genetic variation called apolipoprotein (APOE) ε4 may be more at risk to develop tau protein accumulations in the brain's emotion- and memory-controlling regions, a new study by researchers from The University of Texas Health Science Center at San Antonio and collaborating institutions suggests.

17 Jun 2021

PET/CT images can be used to measure biomarker levels, predict lung cancer outcomes

Tests that analyze biomarkers are used during cancer management to guide treatment and provide information about patient prognosis.

17 Jun 2021

Inhibiting necroptosis could be a novel approach for treating COPD

Research shows that inhibiting necroptosis, a form of cell death, could be a novel therapeutic approach for treating chronic obstructive pulmonary disease, an inflammatory lung condition, also known as emphysema, that makes it difficult to breathe.

17 Jun 2021

Collaborative project seeks to promote equitable care for atrial fibrillation

The American College of Cardiology and Heart Rhythm Society, in collaboration with the Bristol Myers Squibb-Pfizer Alliance, are launching an innovative project to improve management of atrial fibrillation in underserved communities.

17 Jun 2021

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

17 Jun 2021

Study may provide the basis to develop new therapies for urinary tract infections, kidney stones

The normal function of uromodulin, a protein that is made in the kidney and secreted into the urine, remains largely unknown. However, higher levels of uromodulin in the urine are related to lower rates of urinary tract infections and kidney stones, while higher levels of this protein in kidney cells are associated with higher rates of hypertension and chronic kidney disease.

17 Jun 2021

New noninvasive biomarker can be used in the diagnosis of NAFLD

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and can progress to liver cirrhosis, liver failure or cancer. Currently, nonalcoholic steatohepatitis (NASH) diagnosis requires an invasive liver biopsy which can lead to procedural complications.

17 Jun 2021

Medical Condition News

Adding immune oncology drug to chemotherapy improves response in subset of breast cancer patients

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Alarming COVID study indicates long-term loss of gray matter and other brain tissue

Study shows how a specific gut bacterium influences infant immune system

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

Foresight Diagnostics to demonstrate utility of PhasED-Seq technology at ICML meeting

Proven treatment for psychosis has been recognized as standard of care

New details on transport protein could help develop drugs for neurological diseases

APOE ɛ4 carriers with midlife depressive symptoms may be at higher risk of tau accumulation

PET/CT images can be used to measure biomarker levels, predict lung cancer outcomes

Inhibiting necroptosis could be a novel approach for treating COPD

Collaborative project seeks to promote equitable care for atrial fibrillation

Genetically engineering NK cells can destroy tumor-regenerating glioblastoma stem cells

Study may provide the basis to develop new therapies for urinary tract infections, kidney stones

New noninvasive biomarker can be used in the diagnosis of NAFLD

Popular video games may provide effective support for some mental health issues

MicroRNAs in urine could be a promising biomarker to diagnose brain tumors, study reveals

Myocarditis after SARS-CoV-2 vaccine

New technique shows promise as non-invasive intervention for congenital hearing loss

Depression, anxiety and stress during pandemic linked with lower quality sleep

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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