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New efforts to improve the efficacy of nucleotide-based drugs against prostate cancer, bone metastasis

Published in the Advanced Functional Materials, University of Minnesota researcher Hongbo Pang led a cross-institutional study on improving the efficacy of nucleotide-based drugs against prostate cancer and bone metastasis.

21 Apr 2021

HSS’ doctor performs first total wrist replacement surgery with KinematX implant

Sixty-nine-year-old Mark Eisen says he waited seven years for a surgery he hopes will change his life. Last week, he had the first total wrist replacement with KinematX™, a new implant co-designed by Scott Wolfe, MD, chief emeritus of the Hand and Upper Extremity Service at Hospital for Special Surgery (HSS). Dr. Wolfe performed the surgery on April 15.

21 Apr 2021

Field of mathematics reveals a potential gene that causes acute lymphoblastic leukemia

Using a widely known field of mathematics designed mainly to study how digital and other forms of information are measured, stored and shared, scientists at Johns Hopkins Medicine and Johns Hopkins Kimmel Cancer Center say they have uncovered a likely key genetic culprit in the development of acute lymphoblastic leukemia (ALL).

21 Apr 2021

People who regularly use psychoactive substances experienced negative impacts during COVID-19

People who regularly use psychoactive substances report experiencing a variety of negative impacts since the COVID-19 pandemic began, including increased usage and fear of relapse or overdose, highlighting the need for improved supports and services, including better access to safe supply programs, according to a new CAMH survey published in the International Journal of Drug Policy.

21 Apr 2021

Changes to infant gut bacteria and food allergies are linked to C-section birth, ethnicity

Researchers have found a causal link between caesarean section birth, low intestinal microbiota and peanut sensitivity in infants, and they report the effect is more pronounced in children of Asian descent than others, in a recently published paper in the journal of the American Gastroenterological Association.

21 Apr 2021

Inhibition of Meprin Β enzyme can trigger the development of Alzheimer's disease, cancer

Researchers at Johannes Gutenberg University Mainz (JGU) in Germany and the Institute of Molecular Biology of Barcelona in Spain have discovered how the blood plasma protein fetuin-B binds to the enzyme meprin β and used a computer model to visualize their findings.

21 Apr 2021

Fast oscillations in electroencephalography can pinpoint brain tissues responsible for epileptic seizures

Professor Bin He's team at Carnegie Mellon University, in collaboration with the Mayo Clinic, has discovered that fast oscillations in scalp-recorded electroencephalography can pinpoint brain tissues responsible for epileptic seizures.

21 Apr 2021

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation--at least when all is functioning normally.

21 Apr 2021

Researchers study ways to improve pediatric heart transplant outcomes

Scientific research teams in California and Texas have been awarded nearly $1.4 million in grants to study ways to improve pediatric heart transplant outcomes.

21 Apr 2021

Chaperone protein imbalance can play key role in initiating toxic tau buildup in the aging brain

Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain - an early step in the development of Alzheimer's disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by University of South Florida Health (USF Health) neuroscientists suggests.

20 Apr 2021

Study investigates severe lung injuries among e-cigarette users in rural Appalachia

Just as e-cigarette ingredients can vary from one region to another, the health effects of vaping can have regional characteristics as well. A new study out of West Virginia University suggests that rural e-cigarette users are older--and often get sicker--than their urban counterparts.

20 Apr 2021

Researchers reveal a potential therapeutic strategy against T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of leukemia in which too many T-cell lymphoblasts, or immature white blood cells, are found in the bone marrow and blood.

20 Apr 2021

TBI patients face challenges in healthcare utilization, finds study

Patients who suffer from traumatic brain injuries (TBI) often need a great deal of healthcare services after the injury, but the extent of care utilization is unknown.

20 Apr 2021

1 in 6 patients with colorectal cancer found to have inherited genetic mutations

A new Mayo Clinic study bolsters evidence that colorectal cancer is often imprinted in family genes and passed on from one generation to the next.

20 Apr 2021

Nearly 20% of U.S. adults experience chronic pain

Chronic pain is among the most common chronic conditions in the United States, but estimates of its prevalence and impact vary widely.

20 Apr 2021

New nanomedicine device is effective for treating glioblastoma multiforme

A micro-sized polymeric net wrapping around brain tumors, just like a fishing net around a shoal of fish: this is the microMESH, a new nanomedicine device capable to conform around the surface of tumor masses and efficiently deliver drugs.

20 Apr 2021

Study identifies strengths and specific challenges among young autistic drivers

A collaborative study from the Center for Injury Research and Prevention (CIRP) and the Center for Autism Research (CAR) at Children's Hospital of Philadelphia (CHOP) identified clear strengths and a series of specific challenges autistic adolescents experience while learning to drive.

20 Apr 2021

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

Opioid addicts wage a daily war within over whether or not to use a drug whose side effect can be death. If those same addicts, however, had the choice to take an opioid vaccine once or twice a year, their internal struggle could be over.

20 Apr 2021

Federal policy to improve outcomes in sepsis patients was mostly ineffective

The first large-scale, multi-hospital evaluation of an "all or none" federal policy intended to improve outcomes in sepsis patients finds that the guidelines are a wash - on average they neither helped nor hurt despite significant investments in their implementation, according to an analysis by University of Pittsburgh School of Medicine clinician-scientists of nearly a dozen hospitals in one academic health system.

20 Apr 2021

Study shows link between disturbed sleep and increased risk of cardiovascular death in women

For the first time, a study has shown a clear link between the frequency and duration of unconscious wakefulness during night-time sleep and an increased risk of dying from diseases of the heart and blood vessels, and death from any cause, particularly in women.

20 Apr 2021

Medical Condition News

New efforts to improve the efficacy of nucleotide-based drugs against prostate cancer, bone metastasis

HSS’ doctor performs first total wrist replacement surgery with KinematX implant

Field of mathematics reveals a potential gene that causes acute lymphoblastic leukemia

People who regularly use psychoactive substances experienced negative impacts during COVID-19

Changes to infant gut bacteria and food allergies are linked to C-section birth, ethnicity

Inhibition of Meprin Β enzyme can trigger the development of Alzheimer's disease, cancer

Fast oscillations in electroencephalography can pinpoint brain tissues responsible for epileptic seizures

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

Researchers study ways to improve pediatric heart transplant outcomes

Chaperone protein imbalance can play key role in initiating toxic tau buildup in the aging brain

Study investigates severe lung injuries among e-cigarette users in rural Appalachia

Researchers reveal a potential therapeutic strategy against T-cell acute lymphoblastic leukemia

TBI patients face challenges in healthcare utilization, finds study

1 in 6 patients with colorectal cancer found to have inherited genetic mutations

Nearly 20% of U.S. adults experience chronic pain

New nanomedicine device is effective for treating glioblastoma multiforme

Study identifies strengths and specific challenges among young autistic drivers

Scientists receive NIH grant to develop an adjuvant vaccine for opioid use disorder

Federal policy to improve outcomes in sepsis patients was mostly ineffective

Study shows link between disturbed sleep and increased risk of cardiovascular death in women

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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