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Study: Wisdom and loneliness can influence the gut microbial diversity

It may take guts — or more precisely, a diverse gut microbiome — to achieve wisdom and fend off loneliness. Or perhaps it’s the other way around, report UC San Diego researchers.

26 Mar 2021

DAPK3 slows tumor growth by activating fierce-sounding STING pathway

The glow of a panther's eyes in the darkness. The zig-zagging of a shark's dorsal fin above the water. Humans are always scanning the world for threats.

26 Mar 2021

Scientists identify new genetic clues to treat “silent’ stroke

Scientists have identified new genetic clues in people who've had small and often apparently 'silent' strokes that are difficult to treat and a major cause of vascular dementia, according to research funded by the British Heart Foundation (BHF) and published in The Lancet Neurology.

26 Mar 2021

Naloxone can save lives but stigma is preventing its use among newly abstinent opioid users

Opioids are the main driver of fatal drug overdoses in the United States, according to the Centers for Disease Control and Prevention, resulting in 46,802 deaths in 2018, usually because the person stops breathing.

26 Mar 2021

Newly identified pathway controls dangerous overreactions in the body's immune system

Scientists at Sinai Health say they have discovered a new pathway that controls dangerous overreactions in a body's immune system, including deadly forms of hyper-inflammation.

26 Mar 2021

New study may shed light on inflammatory bowel disease

Researchers have found an unexpected synergy between a T-cell stimulatory protein -- the ICOS ligand -- and interleukin-10, an immunoregulatory cytokine, to prevent inflammatory bowel disease in mice.

26 Mar 2021

Researchers use new process to improve deep brain stimulation

Despite having remarkable utility in treating movement disorders such as Parkinson's disease, deep brain stimulation (DBS) has confounded researchers, with a general lack of understanding of why it works at some frequencies and does not at others.

26 Mar 2021

DNMT3a plays a key role in regulating HSC responses to infections

Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections.

26 Mar 2021

New screening method detects cancer biomarkers more effectively

Early screening can mean the difference between life and death in a cancer and disease diagnosis. That's why University of Central Florida researchers are working to develop a new screening technique that's more than 300 times as effective at detecting a biomarker for diseases like cancer than current methods.

26 Mar 2021

Study reveals colorectal cancer risk does not rise after bariatric surgery

Colorectal cancer risk does not rise after bariatric surgery, a study from the University of Gothenburg shows. This finding is important for patients with obesity, and their healthcare professionals, when deciding upon such an operation.

26 Mar 2021

Moffitt researchers use mathematical modeling to help explain outcomes of CAR T-cell therapy

Chimeric antigen receptor T-cell therapy, or CAR T, is a relatively new type of therapy approved to treat several types of aggressive B cell leukemias and lymphomas.

25 Mar 2021

Researchers reveal a mechanistic link in kidney cancer between fat metabolism and obesity

Altered cellular energetics, a hallmark of cancers, has been associated with obesity. However, links between systemic energy regulation and aberrant cancer cell metabolism have been lacking.

25 Mar 2021

UArizona researcher finds a unique approach to tackle both Alzheimer’s disease and diabetes

A University of Arizona Health Sciences researcher examined the role of cholesterol in both Alzheimer's disease and Type 2 diabetes to identify a small molecule that may help regulate cholesterol levels in the brain, making it a potential new therapeutic target for Alzheimer's disease.

25 Mar 2021

Study identifies NCOA3 as a novel therapeutic target for melanoma

For the first time, activation of nuclear receptor coactivator 3 (NCOA3) has been shown to promote the development of melanoma through regulation of ultraviolet radiation (UVR) sensitivity, cell cycle progression and circumvention of the DNA damage response.

25 Mar 2021

Medical Condition News

Study: Wisdom and loneliness can influence the gut microbial diversity

DAPK3 slows tumor growth by activating fierce-sounding STING pathway

Scientists identify new genetic clues to treat “silent’ stroke

Naloxone can save lives but stigma is preventing its use among newly abstinent opioid users

Newly identified pathway controls dangerous overreactions in the body's immune system

New study may shed light on inflammatory bowel disease

Researchers use new process to improve deep brain stimulation

DNMT3a plays a key role in regulating HSC responses to infections

New screening method detects cancer biomarkers more effectively

Study reveals colorectal cancer risk does not rise after bariatric surgery

Moffitt researchers use mathematical modeling to help explain outcomes of CAR T-cell therapy

Researchers reveal a mechanistic link in kidney cancer between fat metabolism and obesity

UArizona researcher finds a unique approach to tackle both Alzheimer’s disease and diabetes

Study identifies NCOA3 as a novel therapeutic target for melanoma

Corticotropin-releasing stress hormone may be linked to increased allergic reactions

Study identifies gene variants that cause metabolic deficiency in the eye

Lupus Research Alliance announces recipients of the 2020 Distinguished Innovator Award

UB receives $1.5 million grant to develop new therapies for oral cancers

ColoradoSPH wins NIH grant to study how air pollutants impact kidney health of sugarcane workers

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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