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Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

Previous research identified the interferon-responsive OAS1 gene as a risk gene for Alzheimer's disease. OAS1 is an enzyme that binds to double-stranded RNA and induces the conformation to create oligoadenylates. They also activate RNase L to break down RNA.

23 Mar 2021

Temple researchers receive CHEST Foundation grant to explore racial disparities in lung function

Lung disease is the third-leading cause of death in the United States. Much of this burden is disproportionately spread across populations of non-Hispanic whites, particularly African Americans who smoke.

23 Mar 2021

Genetic study identifies sex-dependent differences in major psychiatric disorders

An analysis of sex differences in the genetics of schizophrenia, bipolar disorder and major depressive disorders indicates that while there is substantial genetic overlap between males and females, there are noticeable sex-dependent differences in how genes related to the central nervous system, immune system, and blood vessels affect people with these disorders.

23 Mar 2021

Consumption of ultra-processed foods and drinks could raise colorectal cancer risk

Consumption of ultra-processed foods and drink could increase the risk of developing colorectal cancer. This was the conclusion of a large study undertaken by the Barcelona Institute for Global Health, a center supported by the "la Caixa" Foundation, based on questionnaires about food behaviors completed by around 8,000 people in Spain.

23 Mar 2021

Preemies have greater risk of death from chronic diseases in adulthood

The risk of dying from heart disease, chronic lung disease or diabetes in adulthood is twice as high for preemies —premature infants — as for the general population.

23 Mar 2021

New AI platform can help assess vascular diseases

An international team of scientists from Nanyang Technological University, Singapore (NTU Singapore), Brown University and the Massachusetts Institute of Technology (MIT) has developed an artificial intelligence (AI) platform that could one day be used in a system to assess vascular diseases, which are characterised by the abnormal condition of blood vessels.

23 Mar 2021

Study shows cost-effectiveness of total knee replacement for patients with knee osteoarthritis

Knee osteoarthritis is a painful condition that affects over 14 million U.S. adults, many of whom have extreme obesity, defined by body mass index (BMI) greater than 40kg/m2.

23 Mar 2021

Researcher uses alternative approach to find genetic drivers of rare eye disease

An analysis of thousands of genomes from people with and without the rare eye disease known as MacTel has turned up more than a dozen gene variants that are likely causing the condition to develop and worsen for a significant share of patients.

23 Mar 2021

Study reveals new approach for treating diabetic foot ulcers

A discovery involving multiple teams from across Scripps Research has revealed a powerful new approach for treating diabetic foot ulcers, which affect millions of people in the US and often lead to serious complications.

23 Mar 2021

Socioeconomic deprivation linked to large proportion of dementia deaths in England, Wales

A large proportion of dementia deaths in England and Wales may be due to socioeconomic deprivation, according to new research led by Queen Mary University of London.

23 Mar 2021

Nutritional supplement may reduce risk of fatal strokes in patients with rare genetic disorder

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered that a widely used nutritional supplement may significantly reduce the risk of fatal strokes caused by a rare genetic disorder.

23 Mar 2021

Biological “feed-forward” loop contributes to progression of osteoarthritis

An unfortunate biological "feed-forward" loop drives cartilage cells in an arthritic joint to actually contribute to progression of the disease, say researchers at Duke University and Washington University in Saint Louis.

23 Mar 2021

New technique may result in earlier and easier identification of patients with Barrett's esophagus

A new technique for sampling and testing cells from Barrett's esophagus (BE) patients could result in earlier and easier identification of patients whose disease has progressed toward cancer or whose disease is at high risk of progressing toward cancer, according to a collaborative study by investigators at Case Western Reserve University and Johns Hopkins Kimmel Cancer Center (JHKCC).

23 Mar 2021

Researchers use layered double hydroxide to increase neuronal growth in mice with spinal cord injuries

Researchers from the Department of Orthopedics of Tongji Hospital at Tongji University in Shanghai have successfully used a nanobiomaterial called layered double hydroxide (LDH) to inhibit the inflammatory environment surrounding spinal cord injuries in mice, accelerating regeneration of neurons and reconstruction of the neural circuit in the spine.

23 Mar 2021

Medical Condition News

Changes in OASI gene expression increases risk of Alzheimer's and severe COVID-19 infection

Temple researchers receive CHEST Foundation grant to explore racial disparities in lung function

Genetic study identifies sex-dependent differences in major psychiatric disorders

Consumption of ultra-processed foods and drinks could raise colorectal cancer risk

Preemies have greater risk of death from chronic diseases in adulthood

New AI platform can help assess vascular diseases

Study shows cost-effectiveness of total knee replacement for patients with knee osteoarthritis

Researcher uses alternative approach to find genetic drivers of rare eye disease

Study reveals new approach for treating diabetic foot ulcers

Socioeconomic deprivation linked to large proportion of dementia deaths in England, Wales

Nutritional supplement may reduce risk of fatal strokes in patients with rare genetic disorder

Biological “feed-forward” loop contributes to progression of osteoarthritis

New technique may result in earlier and easier identification of patients with Barrett's esophagus

Researchers use layered double hydroxide to increase neuronal growth in mice with spinal cord injuries

Biological feed-forward loop drives cartilage cells in an arthritic joint to contribute to progression of the disease

Screenings for breast cancer and colon cancer returned to near-normal levels by July 2020

Study may help develop effective biosensors for non-invasive diagnosis of prostate cancer

Study reveals heightened mortality and racial disparities for cancer patients diagnosed with COVID-19

Widening ideological gap in the U.S. may contribute to challenges in medical research

Researchers analyze conceptual metaphors used to describe issues associated with depression

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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