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Women are less likely to undergo CABG, may experience worse outcomes after surgery

Women are significantly less likely than men to undergo coronary artery bypass grafting (CABG) using guideline-recommended approaches, which may result in worse outcomes after surgery, according to a scientific presentation at the 57th Annual Meeting of The Society of Thoracic Surgeons.

31 Jan 2021

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

A phase III study examining whether messenger (m)RNA expression correlated with sensitivity or resistance to chemotherapy did not confer a statistically significant advantage in overall survival for patients with resected stage II-III non-small cell lung cancer (NSCLC), according to research presented at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.

31 Jan 2021

New study confirms the effectiveness of LDCT screening in a never-smoker high-risk population

A study presented today by researchers with the Ministry of Health and Welfare in Taiwan confirmed the effectiveness of low-dose computed tomography (LDCT) screening in a pre-defined, never-smoker, high-risk population.

31 Jan 2021

Nivolumab monotherapy is effective treatment option for relapsed malignant mesothelioma

Nivolumab monotherapy is an effective treatment option for relapsed malignant mesothelioma (MM), according to research presented today at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.

31 Jan 2021

LCMC3 trial: Neoadjuvant atezolizumab prior to lung cancer surgery meets primary endpoint

(Primary analysis of the Lung Cancer Mutation Consortium (LCMC) 3 study revealed that neoadjuvant atezolizumab prior to lung cancer surgery was well tolerated by patients and met its primary endpoint of 20% major pathologic response rate, according to research presented today at the International Association for the Study of Lung Cancer's World Conference on Lung Cancer.

31 Jan 2021

Study: Link between protein folding and misfolding can lead to the formation of amyloid fibers

Researchers from Osaka University have described the link between accurate protein folding and misfolding that can lead to the formation of amyloid fibers, which are implicated in neurodegenerative diseases

31 Jan 2021

COVID effect resulted in substantial decline in heart surgery, caused more patient deaths

The most deadly global health crisis in a century has resulted in a substantial decline in overall heart surgery volume and an unexplained increase in deaths after coronary artery bypass grafting, according to late-breaking research presented at the 57th Annual Meeting of The Society of Thoracic Surgeons.

31 Jan 2021

Lung mechanics and hypoxemia in COVID-19 patients with ARDS

To better understand how low blood oxygen level, or hypoxemia, and lung compliance varies in COVIDARDS and how they relate to disease outcomes, researchers developed a dataset of using more than 11,000 COVID-19 patients admitted to the hospital. A research paper published on the medRxiv* preprint server reports their results.

31 Jan 2021

Study reveals effective therapeutic strategy to prevent colorectal cancer progression

Nagoya University researchers and colleagues have revealed that colorectal cancer tissues contain at least two types of fibroblasts (a type of cells found in connective tissue), namely, cancer-promoting fibroblasts and cancer-restraining fibroblasts, and that the balance between them is largely involved in the progression of colorectal cancer.

30 Jan 2021

Researchers examine the connection between lung cancer and COVID-19

On February 27, 2020, the flagship journal of the International Association for the Study of Lung Cancer, the Journal of Thoracic Oncology, published a case study that described two patients from Wuhan, China who recently underwent lung lobectomies for adenocarcinoma and were retrospectively found to have had COVID-19 at the time of surgery.

30 Jan 2021

Discovery offers novel possibilities to target drug-resistant HER2-positive cancers

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells.

29 Jan 2021

RPS-12 protein overproduction appears to trigger breast cancer and other malignancies

Using the developing eye of the fruit fly as a test platform, researchers found that RPS-12 protein overproduction appears to trigger triple-negative breast cancer and possibly some other malignancies.

29 Jan 2021

Study finds locations of early prion protein accumulation in the eye

The earliest eye damage from prion disease takes place in the cone photoreceptor cells, specifically in the cilia and the ribbon synapses, according to a new study of prion protein accumulation in the eye by National Institutes of Health scientists.

29 Jan 2021

Reduced-dose radiotherapy with cisplatin produces good outcomes for HPV-associated oropharyngeal cancer

A combination of reduced-dose radiotherapy using intensity-modulated radiotherapy (IMRT) combined with concurrent cisplatin met the threshold for disease control and quality of life compared to the standard of care for good-risk patients with HPV-associated oropharyngeal squamous cell carcinoma on the NRG Oncology clinical trial NRG-HN002.

29 Jan 2021

Robotic exoskeleton gait training may aid early rehabilitation for stroke

A team of New Jersey researchers has demonstrated that high-dose therapy gait training using robotic exoskeletons may aid early rehabilitation for acute stroke.

29 Jan 2021

Obesity may contribute toward neural tissue vulnerability, exacerbate Alzheimer's disease

New research from the University of Sheffield has found being overweight is an additional burden on brain health and it may exacerbate Alzheimer's disease.

29 Jan 2021

Novel deep learning system can predict cardiovascular risk from CT scans

Coronary artery calcification -- the buildup of calcified plaque in the walls of the heart's arteries -- is an important predictor of adverse cardiovascular events like heart attacks.

29 Jan 2021

Early-life-trauma could affect trajectory of multiple sclerosis development and treatment

Childhood trauma could affect the trajectory of multiple sclerosis development and response to treatment in adulthood, a new study in mice found.

29 Jan 2021

Residential segregation, discriminatory practices impact outcomes of Black lung cancer patients

Structural racism thwarts a large proportion of black patients from receiving appropriate lung cancer care, resulting in worse outcomes and shorter lifespans than white patients with the disease, according to research presented at the 57th Annual Meeting of The Society of Thoracic Surgeons.

29 Jan 2021

Study shows promising outcomes of new mitral valve replacement procedure in high-risk patients

An innovative mitral valve replacement procedure shows promise for high-risk patients in a new University of Miami Miller School of Medicine study led by Joseph Lamelas, M.D., chief and program director of cardiothoracic surgery.

29 Jan 2021

Medical Condition News

Women are less likely to undergo CABG, may experience worse outcomes after surgery

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

New study confirms the effectiveness of LDCT screening in a never-smoker high-risk population

Nivolumab monotherapy is effective treatment option for relapsed malignant mesothelioma

LCMC3 trial: Neoadjuvant atezolizumab prior to lung cancer surgery meets primary endpoint

Study: Link between protein folding and misfolding can lead to the formation of amyloid fibers

COVID effect resulted in substantial decline in heart surgery, caused more patient deaths

Lung mechanics and hypoxemia in COVID-19 patients with ARDS

Study reveals effective therapeutic strategy to prevent colorectal cancer progression

Researchers examine the connection between lung cancer and COVID-19

Discovery offers novel possibilities to target drug-resistant HER2-positive cancers

RPS-12 protein overproduction appears to trigger breast cancer and other malignancies

Study finds locations of early prion protein accumulation in the eye

Reduced-dose radiotherapy with cisplatin produces good outcomes for HPV-associated oropharyngeal cancer

Robotic exoskeleton gait training may aid early rehabilitation for stroke

Obesity may contribute toward neural tissue vulnerability, exacerbate Alzheimer's disease

Novel deep learning system can predict cardiovascular risk from CT scans

Early-life-trauma could affect trajectory of multiple sclerosis development and treatment

Residential segregation, discriminatory practices impact outcomes of Black lung cancer patients

Study shows promising outcomes of new mitral valve replacement procedure in high-risk patients

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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