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Protein aggregation reduces elasticity of blood vessels in the brain

Deposits of a protein called "Medin", which manifest in virtually all older adults, reduce the elasticity of blood vessels during aging and hence may be a risk factor for vascular dementia.

9 Sep 2020

Alcohol intake linked to increased risk of hypertension in adults with Type 2 diabetes

Drinking eight or more alcoholic beverages a week may increase the risk of high blood pressure (also called hypertension) among adults with Type 2 diabetes, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.

9 Sep 2020

Novel drug could improve life expectancy and quality for patients with hard-to-treat cancers

The Sheffield researchers founded the spin-out Modulus Oncology with a team of experienced biotech entrepreneurs to fast-track the drug into clinical testing within two years.

9 Sep 2020

High-intensity focused ultrasound technology shows promising outcomes for prostate cancer

High-intensity focused ultrasound (HIFU) - a technology used to treat localized prostate cancer - has shown adequate control of prostate cancer while avoiding major side effects of surgery or radiation therapy, according to a new study in The Journal of Urology®, Official Journal of the American Urological Association (AUA).

9 Sep 2020

New drug can enhance life expectancy and quality for patients with hard-to-treat cancers

A new drug which could improve life expectancy and quality for patients with hard-to-treat cancers, such as pancreatic cancer and relapsed breast cancer, has been invented by scientists at the University of Sheffield.

9 Sep 2020

Study reveals partially overlapping patterns of brain function in people with anorexia and body dysmorphic disorder

A new UCLA study shows partially overlapping patterns of brain function in people with anorexia nervosa and those with body dysmorphic disorder, a related psychiatric condition characterized by misperception that particular physical characteristics are defective.

9 Sep 2020

Study sheds new light on function and regulation of APOBEC3B in adrenocortical carcinoma

The cover for issue 36 of Oncotarget features, "Knockdown of APOBEC3B is associated with a lower tumor growth in an adrenocortical carcinoma xenograft mouse model," by Gara, et al. which reported that the role of APOBEC3B in adrenocortical carcinoma and the mechanisms through which its expression is regulated in cancer are not fully understood.

9 Sep 2020

New study can advance scientific understanding of the function of astrocytes

New research from Oregon Health & Science University for the first time documents the presence of astrocytes in zebrafish, a milestone that will open new avenues of research into a star-shaped type of glial cell in the brain that is critical for nearly every aspect of brain assembly and function.

9 Sep 2020

New combination therapy helps fight cancer

Radiation causes key changes to immune cells in kidney cancer tumors.T cells in tumors are expanded in blood shortly after radiation, then decrease.

9 Sep 2020

MD Anderson and Astex Pharmaceuticals partner to accelerate clinical evaluation of leukemia therapies

The University of Texas MD Anderson Cancer Center and Astex Pharmaceuticals, Inc., a wholly owned subsidiary of Otsuka Pharmaceutical Co. Ltd., based in Tokyo, Japan, today announce a strategic collaboration agreement aimed at accelerating the clinical evaluation of Astex's pipeline of products for patients with certain types of leukemia, including myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).

8 Sep 2020

Study underscores value of Mass General’s online health tool about Down syndrome

A new software program effectively brings the expertise of Massachusetts General Hospital specialists to many more patients with Down syndrome (DS), according to a study published today in Genetics in Medicine.

8 Sep 2020

New project seeks to understand the origin and role of ecDNA in cancer development

A team of pediatric oncologists led by PD Dr. Anton G. Henssen has set out to further improve our understanding of the mechanisms involved in cancer development and disease progression.

8 Sep 2020

Targeted therapy can provide benefits to lung cancer patients with specific gene mutations

A targeted therapy called capmatinib can provide significant benefits to patients who have advanced lung cancer with specific gene mutations, according to recently published results from a phase two clinical trial.

8 Sep 2020

Combination of gas embolization and chemotherapy can lead to complete tumor regression

Hepatocellular carcinoma is a particularly stubborn form of cancer with few treatments and a high mortality rate.

8 Sep 2020

Study reveals complex immunology behind MIS-C in children with COVID-19

In a recent paper published in the prestigious journal Cell, researchers from Sweden and Italy show that inflammatory response in Multisystem Inflammatory Syndrome in Children associated with coronavirus disease (COVID-19) differs from the cytokine storm found in severe acute illness, involving autoantibodies at the same time and sharing several features with Kawasaki disease.

8 Sep 2020

Six genomics research projects receive grants to address the role of ethnicity in major cancers

Leading cancer scientists working with the New York Genome Center (NYGC) announced today that grants are being awarded to fund six projects that address the role of ethnicity in several major cancer types, taking advantage of the diversity of patients being treated at health care institutions throughout the New York City area.

8 Sep 2020

Research finds different patterns of blood use in the brains of older women with Type 2 diabetes

A University of Houston researcher is reporting that the brains of older women with Type 2 diabetes do not use as much oxygenated blood as those who don't have the disease.

8 Sep 2020

Nanotechnological drug delivery system enhances the effectiveness of melanoma treatment

Researchers at Tel Aviv University, led by Prof. Ronit Satchi-Fainaro of TAU's Department of Physiology and Pharmacology at the Sackler School of Medicine, have developed an innovative nanotechnological drug delivery system that significantly enhances the effectiveness of treatment for the aggressive skin cancer melanoma.

8 Sep 2020

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein's buildup and neurological decline associated with these disorders, suggests a pre-clinical study from researchers at Penn Medicine and Mayo Clinic.

8 Sep 2020

High levels of blood clotting factor V in severe COVID‐19 associated with worse outcomes

Patients hospitalized with severe COVID-19 infections who have high levels of the blood clotting protein factor V are at elevated risk for serious injury from blood clots such as deep vein thrombosis or pulmonary embolism, investigators at Massachusetts General Hospital (MGH) have found.

8 Sep 2020

Medical Condition News

Protein aggregation reduces elasticity of blood vessels in the brain

Alcohol intake linked to increased risk of hypertension in adults with Type 2 diabetes

Novel drug could improve life expectancy and quality for patients with hard-to-treat cancers

High-intensity focused ultrasound technology shows promising outcomes for prostate cancer

New drug can enhance life expectancy and quality for patients with hard-to-treat cancers

Study reveals partially overlapping patterns of brain function in people with anorexia and body dysmorphic disorder

Study sheds new light on function and regulation of APOBEC3B in adrenocortical carcinoma

New study can advance scientific understanding of the function of astrocytes

New combination therapy helps fight cancer

MD Anderson and Astex Pharmaceuticals partner to accelerate clinical evaluation of leukemia therapies

Study underscores value of Mass General’s online health tool about Down syndrome

New project seeks to understand the origin and role of ecDNA in cancer development

Targeted therapy can provide benefits to lung cancer patients with specific gene mutations

Combination of gas embolization and chemotherapy can lead to complete tumor regression

Study reveals complex immunology behind MIS-C in children with COVID-19

Six genomics research projects receive grants to address the role of ethnicity in major cancers

Research finds different patterns of blood use in the brains of older women with Type 2 diabetes

Nanotechnological drug delivery system enhances the effectiveness of melanoma treatment

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

High levels of blood clotting factor V in severe COVID‐19 associated with worse outcomes

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