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Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein's buildup and neurological decline associated with these disorders, suggests a pre-clinical study from researchers at Penn Medicine and Mayo Clinic.

8 Sep 2020

High levels of blood clotting factor V in severe COVID‐19 associated with worse outcomes

Patients hospitalized with severe COVID-19 infections who have high levels of the blood clotting protein factor V are at elevated risk for serious injury from blood clots such as deep vein thrombosis or pulmonary embolism, investigators at Massachusetts General Hospital (MGH) have found.

8 Sep 2020

Researchers aim to improve digital thermal imaging as a tool for monitoring cancer

Thermal imaging has been available for decades to detect temperature differences on the skin that could signal breast cancer without exposing patients to radiation, although the method is not as reliable as mammography.

8 Sep 2020

Microglia-targeting nanotherapeutics for treatment of neurodegenerative disorders

Inspired by the need for new and better therapies for neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease, Rutgers University researchers are exploring the link between uncontrolled inflammation within the brain and the brain's immune cells, known as microglia.

8 Sep 2020

Personalized determination of genetic factors may improve treatment for polycythaemia vera

Polycythaemia vera is a chronic malignant disease of the haematopoietic system and is treated with interferon-alpha-based drugs, in most cases with long-lasting success. However, in some cases this therapy is unsuccessful for reasons that are not yet understood.

8 Sep 2020

Fight for Sight partners with Diabetes UK to investigate link between eye disease and COVID-19

Eye research charity Fight for Sight is partnering with Diabetes UK to investigate if people with the eye disease diabetic retinopathy are at greater risk of developing complications from Covid-19, in a study that hopes to save lives.

8 Sep 2020

Study links brain astrocyte dysfunction to Parkinson’s disease pathology

A new study using induced pluripotent stem cell technology links astrocyte dysfunction to Parkinson’s disease pathology.

8 Sep 2020

Limited gut inflammation in COVID-19

A new study by researchers at the Icahn School of Medicine at Mount Sinai and published on the preprint server medRxiv in September 2020 shows that gut infection with this virus produces primarily mucosal immunity but also a limited inflammatory response.

8 Sep 2020

Novel markers may predict patient response to immune checkpoint inhibitors

For many individuals with different types of cancer, immune checkpoint inhibitors can effectively boost their immune system to fight their disease, but not all patients benefit from these medications.

7 Sep 2020

New medical instruments with smart sensors can improve surgery, therapy for cardiac diseases

Researchers developed a new class of medical instruments equipped with an advanced soft electronics system that could dramatically improve the diagnoses and treatments of a number of cardiac diseases and conditions.

7 Sep 2020

Study shows how mutations in DNA packaging machines can drive cancer development

Like wrenches made of Legos, SWI/SNF chromatin remodeling complexes tighten or loosen DNA in our cells to control how genes are turned on and made into proteins.

7 Sep 2020

New insights into how the brain can induce diabetes remission in rodents

In rodents with type 2 diabetes, a single surgical injection of a protein called fibroblast growth factor 1 can restore blood sugar levels to normal for weeks or months. Yet how this growth factor acts in the brain to generate this lasting benefit has been poorly understood.

7 Sep 2020

A potential new way of treating Alzheimer’s Disease

In this interview, Dr. Brad. L. Heckman speaks to News-Medical about a new pathway that could potentially treat Alzheimers disease.

7 Sep 2020

D-dimer - A sensitive novel biomarker of COVID-19 mortality

Now, a new study published on the preprint server medRxiv* reports the use of D-dimer in predicting the risk of mortality in COVID-19.

7 Sep 2020

Rehabilitation speeds coronavirus recovery

Now, a team of researchers at the University Clinic in Innsbruck in Austria has found that the long-term lung and heart damage in coronavirus disease (COVID-19) patients who recovered tend to improve over time.

7 Sep 2020

Study: Patients with thyroid inflammation may be at greater risk of developing anxiety

Patients with autoimmune inflammation of their thyroid may be at greater risk of developing anxiety, according to a study being presented at e-ECE 2020.

7 Sep 2020

Study may provide the basis for better diagnostic, therapeutic approaches to blood diseases

The hemoglobin in the red blood cells ensures that our body cells receive sufficient oxygen. When the blood pigment is broken down, "heme" is produced, which in turn can influence the protein cocktail in the blood.

5 Sep 2020

Common class of drugs may be associated with increased risk of cognitive decline

A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad array of conditions, from allergies and colds to hypertension and urinary incontinence, may be associated with an increased risk of cognitive decline, particularly in older adults at greater risk for Alzheimer's disease.

5 Sep 2020

IU researcher receives NCI grant to study side effects of cancer treatment

A researcher at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center has been awarded a five-year, $5.7 million National Cancer Institute grant to evaluate long-term health outcomes for cancer patients who receive platinum-based chemotherapies.

5 Sep 2020

Tailored obesity intervention program offers hope for weight loss in underserved patients

Low-income Louisiana patients enrolled in a tailored obesity intervention program lost much more weight than counterparts receiving usual care. Study results were published this week in The New England Journal of Medicine.

5 Sep 2020

Medical Condition News

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

High levels of blood clotting factor V in severe COVID‐19 associated with worse outcomes

Researchers aim to improve digital thermal imaging as a tool for monitoring cancer

Microglia-targeting nanotherapeutics for treatment of neurodegenerative disorders

Personalized determination of genetic factors may improve treatment for polycythaemia vera

Fight for Sight partners with Diabetes UK to investigate link between eye disease and COVID-19

Study links brain astrocyte dysfunction to Parkinson’s disease pathology

Limited gut inflammation in COVID-19

Novel markers may predict patient response to immune checkpoint inhibitors

New medical instruments with smart sensors can improve surgery, therapy for cardiac diseases

Study shows how mutations in DNA packaging machines can drive cancer development

New insights into how the brain can induce diabetes remission in rodents

A potential new way of treating Alzheimer’s Disease

D-dimer - A sensitive novel biomarker of COVID-19 mortality

Rehabilitation speeds coronavirus recovery

Study: Patients with thyroid inflammation may be at greater risk of developing anxiety

Study may provide the basis for better diagnostic, therapeutic approaches to blood diseases

Common class of drugs may be associated with increased risk of cognitive decline

IU researcher receives NCI grant to study side effects of cancer treatment

Tailored obesity intervention program offers hope for weight loss in underserved patients

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