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New nanoconjugate blocks dissemination of tumor cells in animal models of acute myeloid leukemia

The nanoparticle targets only leukemic cells and therefore would reduce the severe adverse effects of current treatments.

9 Jul 2020

People with arthritis report worsening symptoms during Covid-19 lockdown

People with arthritis experienced a ‘roller coaster’ of emotions and saw their symptoms worsen during the Covid-19 lockdown – according to research from the University of East Anglia.

9 Jul 2020

New grant added to Stroke Foundation’s research program

A new research grant, focused on stopping stroke before it happens, has been added to the Stroke Foundation’s well-established research program.

9 Jul 2020

UniSA researchers pioneer new method to more accurately diagnose Parkinson’s disease

University of South Australia researchers are pioneering a new method to more accurately diagnose Parkinson’s disease, a neurodegenerative brain disorder which affects around 70,000 Australians, resulting in a loss of control of body movements.

9 Jul 2020

siRNA therapeutics can reduce off-target side effects of anticancer drugs

Small interfering RNA (siRNA) has shown tremendous potential for treating human diseases in the past decades.

9 Jul 2020

Law enforcement and community partnership screen children for PTSD

The Child Trauma Response Team, innovative policy, and community-based organization partnership demonstrated success at screening and treating children for post-traumatic stress disorder (PTSD) immediately following incidents of intimate partner violence, according to a Rutgers-led study published in the Journal of Interpersonal Violence.

9 Jul 2020

PRMT5 inhibitors can help treat advanced melanoma

Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy.

9 Jul 2020

New research shows promise for treating neuropsychiatric diseases

When trying to complete a task we are constantly bombarded by distracting stimuli. How does the brain filter out these distractions and enable us to focus on the task at hand?

9 Jul 2020

Study provides evidence on non-invasive diagnostic procedures for people with suspected CHD

The German Institute for Quality and Efficiency in Health Care (IQWiG) used an evidence map to investigate to what extent informative evidence exists on the benefit and harm of the diagnostic procedures "non-invasive computed tomography angiography" (CTA) and "stress MRI" in people with suspected coronary heart disease (CHD).

9 Jul 2020

Breast cancer simulation models can guide screening recommendations for women

Chest radiation is used to treat children with Hodgkin and non-Hodgkin lymphoma as well as lung metastases in various solid tumors.

9 Jul 2020

Researchers to create AI-based pill to precisely diagnose gastrointestinal cancers

A team led by University of Saskatchewan (USask) researcher Khan Wahid has been awarded $250,000 from the federal New Frontiers in Research Fund to create a new pill-sized capsule that uses artificial intelligence (AI)-enabled sensing to diagnose gastrointestinal cancers and bleeding earlier and more precisely than is currently possible.

9 Jul 2020

New research can help overcome challenges in diabetes research

Scientists focused on finding better treatments or cures for types 1 or 2 diabetes are painfully aware of current limitations, including having to use animal tissue in studies that often don't translate to human trials.

9 Jul 2020

Experimental drug for rare ALS shows promise in early clinical trial

An experimental drug for a rare, inherited form of amyotrophic lateral sclerosis (ALS) has shown promise in a phase 1/phase 2 clinical trial conducted at Washington University School of Medicine in St. Louis, Massachusetts General Hospital in Boston and other sites around the world and sponsored by the pharmaceutical company Biogen Inc.

8 Jul 2020

New method helps pinpoint new potential therapeutic targets for lupus

A team of researchers from Children's Hospital of Philadelphia (CHOP) used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

8 Jul 2020

Blocking tumor-promoting protein could bolster immunotherapy's effectiveness, study suggests

While immunotherapy -- a form of treatment that uses the body's immune system to recognize, attack and kill tumor cells -- has given hope to people across the globe, it fails in a significant proportion of cancer patients.

8 Jul 2020

Study aims to more accurately define methods for measuring delirium severity

In a study published in the journal Dementia and Geriatric Cognitive Disorder, researchers reported on their effort to improve and validate tools used to assess the severity of a condition called delirium, an acute confusional state often experienced by older hospitalized patients.

8 Jul 2020

Texas A&M researchers are developing a wrist-worn system to monitor blood pressure during sleep

High blood pressure is the single biggest risk factor for heart disease, stroke and other health problems. The only way to know if you're at risk is to have it checked often.

8 Jul 2020

Study reveals how overactive immune cells aggravate heart valve disease

A new study using organ-on-a-chip technology reveals how overactive immune cells aggravate heart valve disease and how this damaging hyperactivity could potentially be controlled.

8 Jul 2020

Cocktail of chemotherapy drugs may be safe, effective for patients with metastatic pancreatic cancer

Pancreatic cancer carries a poor prognosis, and it often goes undetected until advanced stages. A new BJS (British Journal of Surgery) study indicates that a certain cocktail of chemotherapy drugs may be a safe and effective treatment option for patients with a metastatic form of the disease.

8 Jul 2020

Parent‐specific effects on child's risk of developing asthma and allergies

New research found that, compared with a father's traits related to allergies and asthma, a mother's traits create a higher risk that a child will develop these same traits in early childhood.

8 Jul 2020