Medical Condition News

RSS

Plasma monitoring of EGFR mutations in NSCLC may help predict resistance to tyrosine kinase inhibitors

Oncotarget Volume 11, Issue 11 reported that at clinical progression, 64 EGFR T790M plasma positive patients were subjected to second line-treatment with osimertinib and strictly monitored during the first month of therapy.

22 Mar 2020

Discovery shows a novel opportunity for DOT1L inhibitors in cancer treatment

Oncotarget Volume 11, Issue 11 reported that in order to understand the molecular mechanism of the dependency in MM, the research team examined gene expression changes upon DOT1L inhibition in sensitive and insensitive cell lines and discovered that genes belonging to the endoplasmic reticulum stress pathway and protein synthesis machinery were specifically suppressed in sensitive cells.

22 Mar 2020

New drug can alleviate the side effects of tricyclic antidepressants

About one in five Danes are affected by depression at some point in their lives. The severe depressions may be treated with the so-called 'tricyclic antidepressants', an antidepressant drug that is more effective than the drugs used for mild and moderate depressions.

22 Mar 2020

Study uncovers a new childhood-onset neurodegenerative disorder

A study has uncovered a new neurodegenerative disorder in which children experience developmental regression and severe epilepsy.

21 Mar 2020

Preclinical study characterizes the binding affinity and selectivity of a selective FLT3 inhibitor

Oncotarget Volume 11, Issue 11 reported that in this preclinical study, we characterized the binding affinity and selectivity of quizartinib, a small-molecule inhibitor of FLT3, and AC886, the active metabolite of quizartinib, compared with those of other FLT3 inhibitors.

21 Mar 2020

Older cancer patients taking multiple medications are at higher risk of hospitalization

As adults age, they accumulate a number of medications for chronic conditions. Older patients take anywhere between 5-15 medications per year, which increases the risk that some of the drugs will counteract each other.

21 Mar 2020

C-Path awarded FDA grant to establish Rare Disease Clinical Outcome Assessment Consortium

The U.S. Food and Drug Administration's Center for Drug Evaluation and Research has funded a cooperative agreement to establish a Rare Disease Clinical Outcome Assessment Consortium.

21 Mar 2020

Standardized test for dementia diagnosis can now be used in seven languages in India

A standardized test that can now be used in the seven main languages in India will support the diagnosis of dementia and mild cognitive impairment.

20 Mar 2020

New UCI-led study reveals how skin cells prepare to heal wounds

Scientists have revealed how skin cells prepare to heal, potentially leading to better understanding of healing within diabetes.

20 Mar 2020

AI may help predict tumor sensitivity to systemic cancer therapies

Using standard-of-care computed tomography scans in patients with advanced non-small cell lung cancer, researchers utilized artificial intelligence to train algorithms to predict tumor sensitivity to three systemic cancer therapies.

20 Mar 2020

Immunotherapy treatment shows promise for some patients with advanced rare cancers

A study conducted by researchers at The University of Texas MD Anderson Cancer Center demonstrated acceptable toxicity and anti-tumor activity in patients with four types of advanced, hard-to-treat rare cancers.

20 Mar 2020

Research provides better understanding of how tremor happens

Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital have improved our understanding of how tremor -- the most common movement disorder -- happens, opening the possibility of novel therapies for this condition.

19 Mar 2020

The cost of excessive sugar in the diet

A new study from the MRC London Institute of Medical Sciences, in the UK, reports that while eating foods rich in sugar does not necessarily make you fat, they can make you very sick. They do this by increasing the level of a compound called uric acid in the blood. The study is published in the journal Cell Metabolism in March 2020.

19 Mar 2020

Participation of people with diabetes in online support groups associated with poorer health

Diabetes is a disease that affects people's lives more in the long term and requires emotional support and information. It is increasingly common for people with diabetes to participate in digital communities and seek help in so-called OSGs (online support groups) to share experiences and glean information.

19 Mar 2020

Research aimed at increasing shelf life of radiation drugs offers hope for cancer patients

People with hard-to-reach cancers in the kidney, gut and prostate will have improved hope for early diagnosis and treatment with new research aimed at increasing the shelf life of revolutionary radiation drugs.

19 Mar 2020

Substances linked to bladder cancer found in the urine of e-cigarette users

An analysis of evidence from multiple scientific studies found six substances that have a strong link to bladder cancer in the urine of people who had used electronic cigarettes and sometimes other tobacco products, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and NYU Langone Health reported.

19 Mar 2020

Medical Condition News

Plasma monitoring of EGFR mutations in NSCLC may help predict resistance to tyrosine kinase inhibitors

Discovery shows a novel opportunity for DOT1L inhibitors in cancer treatment

New drug can alleviate the side effects of tricyclic antidepressants

Study uncovers a new childhood-onset neurodegenerative disorder

Preclinical study characterizes the binding affinity and selectivity of a selective FLT3 inhibitor

Older cancer patients taking multiple medications are at higher risk of hospitalization

C-Path awarded FDA grant to establish Rare Disease Clinical Outcome Assessment Consortium

Standardized test for dementia diagnosis can now be used in seven languages in India

New UCI-led study reveals how skin cells prepare to heal wounds

AI may help predict tumor sensitivity to systemic cancer therapies

Immunotherapy treatment shows promise for some patients with advanced rare cancers

Research provides better understanding of how tremor happens

The cost of excessive sugar in the diet

Participation of people with diabetes in online support groups associated with poorer health

Research aimed at increasing shelf life of radiation drugs offers hope for cancer patients

Substances linked to bladder cancer found in the urine of e-cigarette users

Dietary sugar has negative impact on health independent of obesity

Study offers new insight into genetic alterations associated with osteosarcoma

Revolutionary technology could help identify more effective cancer drug combinations

Mental stress may be a stronger predictor of repeat heart attack

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Latest News