Study shows that risk of autoimmune disease lupus is higher in females

The US prevalence of the autoimmune disease lupus is 72.8 cases per 100,000 individuals, according to an analysis of population-based registries. The analysis, which is published in Arthritis & Rheumatology, found that the rate is 9 times higher for females than males (128.7 vs. 14.6 per 100,000), and it's highest among American Indians/Alaska Natives and Black females.

The study's investigators estimate that in 2018, a total of 204,295 persons in the United States had lupus.

This meta-analysis is a culmination of almost two decades of work from a network of five Centers of Disease Control and Prevention-funded population-based registries and provides prevalence estimates for systemic lupus erythematosus among the major racial/ethnic demographics in the United States. These detailed estimates on how many Americans are affected by lupus may have implications for the various stakeholders who study and treat the disease."

Peter M. Izmirly, MD, Study Lead Author, NYU School of Medicine

Journal reference:

Izmirly, P. M., et al. (2021) Prevalence of Systemic Lupus Erythematosus in the United States: Estimates from a Meta‐Analysis of the Centers for Disease Control and Prevention National Lupus Registries. Arthritis & Rheumatology.


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