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Researchers discover key mechanism in insulin release by cholesterol metabolite

Insulin which is released by pancreatic beta-cells is the main regulator of blood sugar. Previous and current studies by a research group at Lund University in Sweden have identified around hundred different receptors on the surface of the beta-cells, with a diverse functional impact on the beta-cells.

31 Oct 2019

Discovery has potential to put the brakes on Parkinson's 'runaway train'

Researchers at the University of Dundee have made a discovery they believe has the potential to put the brakes on the 'runaway train' that is Parkinson's disease.

31 Oct 2019

Study identifies a kinase as potential target to treat heart failure

An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies.

31 Oct 2019

Optometrists reduce opioid prescription without increasing pain

Optometrists at the University of Michigan have introduced a new approach to prescribing opioids in an effort to help curb the nation’s opioid epidemic.

31 Oct 2019

Doctors report first death from fecal microbiota transplant

Details of an investigational study have emerged after a man died following a fecal microbiate transplant. The events prompted the FDA to set new safety guidelines for the practice.

31 Oct 2019

REANIMA project may overturn paradigms that underlie regenerative cardiology research

Research into new endogenous mechanisms of tissue regeneration is an innovative research avenue in cardiac regeneration.

31 Oct 2019

New deep learning tool will advance personalized medicine for musculoskeletal diseases

Personalized medicine has stirred the imagination of drugs and therapies that are individually tailored to patients.

31 Oct 2019

Common early sign of cardiovascular disease associated with cancer risk

A Mayo Clinic-led study involving 488 cardiac patients whose cases were followed for up to 12 years finds that microvascular endothelial dysfunction, a common early sign of cardiovascular disease, is associated with a greater than twofold risk of cancer.

31 Oct 2019

Researchers identify genes linked to most severe symptoms of multiple sclerosis

In a bid to determine factors linked to the most debilitating forms of multiple sclerosis, Johns Hopkins Medicine researchers say they have identified three so-called "complement system" genes that appear to play a role in MS-caused vision loss.

From Johns Hopkins Medicine 31 Oct 2019

Study finds altered brain asymmetry in autism spectrum disorder

The left and right halves of our brains develop differently, as each hemisphere 'specialises' in certain functions. For example, for most people the left hemisphere--controlling the right hand--is dominant for language.

31 Oct 2019

LLNL leads multi-institutional collaboration in modeling protein interactions linked to cancer

Computational scientists, biophysicists and statisticians from Lawrence Livermore National Laboratory and Los Alamos National Laboratory are leading a massive multi-institutional collaboration that has developed a machine learning-based simulation for next-generation supercomputers capable of modeling protein interactions and mutations that play a role in many forms of cancers.

31 Oct 2019

Adults in least walkable neighborhoods more likely to have high predicted cardiovascular risk

A study led by researchers from St. Michael's Hospital of Unity Health Toronto and ICES found that people living in neighborhoods considered to be the least walkable were up to 33 per cent more likely to have a high predicted 10-year cardiovascular risk compared to individuals living in the most walkable neighborhoods.

31 Oct 2019

$UTSA scientists study osteoporotic bone fractures to rethink treatment$

UTSA scientists study osteoporotic bone fractures to rethink treatment

About half of all women in the U.S. will suffer a bone fracture due to osteoporosis. For women, the incidence of this condition is greater than that of heart attack, stroke and breast cancer combined.

31 Oct 2019

UW Medicine expert highlights healthcare disparities in black women

Dr. Kemi Doll, a UW Medicine gynecologic oncologist, has long studied endometrial cancer. It's work that reflects a bigger issue, she says: "Healthcare for black women isn't really the same as it is for everyone else, especially when it comes to reproductive care."

31 Oct 2019

Research forum to present results of novel anti-obesity medications

Rhythm Pharmaceuticals and Novartis will present findings from the latest stages of clinical evaluation of new anti-obesity medications during a special late-breaking research forum titled "Emerging Pharmacological Anti-obesity Therapies."

31 Oct 2019

Novel method for aggressive breast cancer detection

A new study in rats published in the journal Cell Reports shows that the pattern of RNA molecules produced within certain immune cells called macrophages, found within breast cancers (tumor-associated macrophages, TAMs), can tell whether the tumor is cancerous or not and indicate the type of outcome. The same pattern is present in humans as in mice. This makes it directly useful in predicting the nature of a breast tumor and its outcome.

30 Oct 2019

Proton radiation therapy can help treat patients with hepatocellular carcinoma

Two new studies support and inform the use of proton radiation therapy to treat patients with hepatocellular carcinoma (HCC), a common but often fatal type of liver cancer for which there are limited treatment options. One study (Sanford et al.) suggests that proton radiation, compared to traditional photon radiation, can extend overall survival with reduced toxicity.

30 Oct 2019