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Opioids do not improve quality of life or depression in OA patients

New research presented at the 2019 ACR/ARP Annual Meeting suggests that opioids contribute no measurable benefit to quality of life or depression for patients with osteoarthritis (OA).

11 Nov 2019

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Impaired liver function during pregnancy may alter gut bacteria composition and increase the risk of obesity in children, according to results presented at The Society for Endocrinology Annual Conference.

11 Nov 2019

Methotrexate appears to facilitate bone remodeling in patients with osteoarthritis

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis.

11 Nov 2019

Psoriasis onset determines whether arthritis or psoriasis starts first in people with psoriatic arthritis

In a new study presented at the 2019 ACR/ARP Annual Meeting, researchers found that the age of psoriasis onset determines whether arthritis or psoriasis starts first in people with psoriatic arthritis.

11 Nov 2019

Optimal therapy for Down syndrome arthropathy remains unclear, reveals study

A new study found that patients with Down syndrome arthropathy continue to have an approximate year-long delay in diagnosis from the onset of their symptoms, and that optimal therapy for this condition remains unclear.

11 Nov 2019

Tocilizumab more effective than rituximab in achieving low disease activity in RA patients

New research discovered that tocilizumab is more effective than rituximab in achieving low disease activity in patients with rheumatoid arthritis whose synovial tissue show a low level of B cell infiltration and did not respond to conventional synthetic disease-modifying anti-rheumatic drugs (conventional synthetic DMARDs) or tumor necrosis factor inhibitors first.

11 Nov 2019

Study: Combination tests can predict severe acute kidney injury in critically ill children

Combining 2 tests can improve predictions of severe acute kidney injury in children in intensive care.

10 Nov 2019

Weight-loss surgeries can lead to better diabetes control in older adults

While weight-loss surgeries are not usually performed in people above the age of 65, a new study shows that these procedures can lead to successful weight loss and better diabetes control in older adults.

10 Nov 2019

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, adenosine deaminase 2 (ADA2) in the peripheral blood is a sensitive, specific biomarker for macrophage activation syndrome, a potentially life-threatening complication of systemic juvenile idiopathic arthritis (systemic JIA)

10 Nov 2019

Biologics can be used effectively for both elderly-onset and young-onset RA patients

According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, both patients with rheumatoid arthritis whose disease onset occurred at an older age and those whose disease onset occurred earlier in life have similar improvements in clinical disease at 48 weeks after starting biologic disease-modifying antirheumatic drugs, as well as similar drug maintenance and adverse events discontinuation rates.

10 Nov 2019

Atmospheric and environmental changes linked to organ-specific lupus flares

New research findings presented at the 2019 ACR/ARP Annual Meeting found a strong association between changes in atmospheric and environmental variables 10 days before a clinic visit and organ-specific lupus flares in patients with systemic lupus erythematosus.

10 Nov 2019

Higher risk for hospitalization among dialysis patients in communities with more Black residents

Patients with kidney failure who receive hemodialysis at US clinics located in residential areas with a high percentage of Black residents are more likely to be hospitalized than those who receive hemodialysis in communities with a lower percentage of Black residents.

10 Nov 2019

Common muscle relaxant linked to severe confusion in patients with kidney dysfunction

One in 25 patients with very low kidney function were admitted to hospital with severe confusion and other cognitive-related symptoms a few days after being prescribed a common muscle relaxant.

10 Nov 2019

HCC and cirrhosis-related deaths may be prevented by lifestyle modifications

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that a substantial burden of hepatocellular carcinoma and cirrhosis-related deaths may be prevented by lifestyle modifications to diet, alcohol use and exercise.

10 Nov 2019

Botanical product kratom may cause liver toxicity and injury, study finds

Data from a new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that kratom, a popular and widely available product, may cause liver toxicity and severe liver injury.

10 Nov 2019

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Diabetic kidney disease remains one of the most intractable complications of diabetes. Progress has been made using glycemic and blood pressure control, but the search continues for improved treatments for the estimated one in four adults with diabetes who has some level of nephropathy and continues at risk for eventual kidney failure.

10 Nov 2019

Preclinical data on new drug combination to treat neuroblastoma published

Neuroblastoma is the most common cancer outside of the brain in infants and young children and often fails to respond to therapy. Though it can appear in several areas of the body, it commonly develops as a solid tumor most frequently found in or adjacent to the adrenal glands, which sit atop the kidneys.

10 Nov 2019

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells.

10 Nov 2019

Vitamin D, fish oil supplements do not help preserve kidney health in people with type 2 diabetes

Supplements of vitamin D and omega-3 fatty acids (often sold as fish oil) do not help people with type 2 diabetes stave off chronic kidney disease, according to findings from the largest clinical study to date of the supplements in this patient population.

10 Nov 2019

Study reveals safety, efficacy of live zoster vaccine for people taking TNF inhibitors

According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, the live zoster virus vaccine is safe for people who are currently receiving tumor necrosis factor inhibitor (TNFi) biologic therapies for various indications.

10 Nov 2019

Medical Condition News

Opioids do not improve quality of life or depression in OA patients

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Methotrexate appears to facilitate bone remodeling in patients with osteoarthritis

Psoriasis onset determines whether arthritis or psoriasis starts first in people with psoriatic arthritis

Optimal therapy for Down syndrome arthropathy remains unclear, reveals study

Tocilizumab more effective than rituximab in achieving low disease activity in RA patients

Study: Combination tests can predict severe acute kidney injury in critically ill children

Weight-loss surgeries can lead to better diabetes control in older adults

Study shows ADA2 is a sensitive, specific biomarker for macrophage activation syndrome

Biologics can be used effectively for both elderly-onset and young-onset RA patients

Atmospheric and environmental changes linked to organ-specific lupus flares

Higher risk for hospitalization among dialysis patients in communities with more Black residents

Common muscle relaxant linked to severe confusion in patients with kidney dysfunction

HCC and cirrhosis-related deaths may be prevented by lifestyle modifications

Botanical product kratom may cause liver toxicity and injury, study finds

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Preclinical data on new drug combination to treat neuroblastoma published

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

Vitamin D, fish oil supplements do not help preserve kidney health in people with type 2 diabetes

Study reveals safety, efficacy of live zoster vaccine for people taking TNF inhibitors

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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