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Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Researchers believe that autism is caused by mutations that occur sporadically in the egg or sperm or during pregnancy.

26 Nov 2019

Novel diagnostic method for rapid measurement of celiac disease antibodies

Point-of-care testing is a rapidly growing sector, bringing medical testing from central laboratories to where the patient is receiving care.

26 Nov 2019

Looking for the source: new routes for allergy treatment

A new multinational study has reported a very full account of the B lymphocytes that produce group E antibodies, also called IgE (Immunoglobulin E), that are behind allergic reactions, which are common in up to a third of the world’s population.

26 Nov 2019

Oligomerix and Feinstein Institutes publish preclinical data of Alzheimer's disease treatment

Oligomerix, Inc., a privately held company pioneering the development of tau oligomer inhibitors for Alzheimer's disease and related neurodegenerative disorders, and the Feinstein Institutes for Medical Research announced today the publication of preclinical data demonstrating that an oral small molecule drug inhibits the formation of neurotoxic tau oligomers in an animal model of tau aggregation most relevant to AD.

26 Nov 2019

New wearable sensor for non-invasive gout detection

Biomedical scientists are working hard to create more pain-free methods of disease detection and treatment. A simple blood test is highly informative but arouses intense anxiety in many people. Now a new paper published in the journal Nature Biotechnology on November 25, 2019, reports on a new wearable sensor that can be successfully adapted to mass production, is flexible, and can be used to produce readouts of metabolites and nutrients in the blood based on a sweat analysis.

26 Nov 2019

Skiing associated with reduced risk of vascular dementia but not Alzheimer’s

Half as many diagnosed with depression, a delayed manifestation of Parkinson's, a reduced risk of developing vascular dementia - but not Alzheimer's.

26 Nov 2019

Aerobic exercise and heart-healthy diet may slow cognitive decline in older adults with CIND

Cognitive impairment without dementia (CIND), or mild cognitive impairment, is a condition that affects your memory and may put you at risk for Alzheimer's disease and dementia.

26 Nov 2019

Study reveals novel pathway to target colorectal cancer

While the emergence of precision medicine and immunotherapy has greatly improved outcomes for patients with colorectal cancer, new approaches are still needed for patients with late-stage disease who do not respond to these therapies.

26 Nov 2019

Researchers win grants to find innovative treatments for debilitating skin diseases

National leaders in research to cure debilitating skin diseases based at the Gates Center for Regenerative Medicine on the University of Colorado Anschutz Medical Campus have won a second NIH grant to further investigations of innovative treatments.

26 Nov 2019

Kessler Foundation participates in new study to test innovative treatment for hand paralysis

Kessler Foundation is participating in a phase II multi-site study of an innovative treatment to improve hand function in stroke survivors. Olga Boukrina, PhD, research scientist in the Center for Stroke Rehabilitation Research, is the site's principal investigator.

26 Nov 2019

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

While estrogen receptor - + breast cancers express high levels of three anti-apoptotic Bcl-2 family members, pharmacological inhibition of Bcl-2 and/or Bcl-xL fails to induce cell death in ER + breast cancer cell lines, due to rapid and robust Mcl-1 upregulation.

26 Nov 2019

Giving a shot of ketamine could help heavy drinkers reduce alcohol intake

A one-off dose of ketamine could help heavy drinkers reduce their alcohol intake, finds a new UCL experimental study.

26 Nov 2019

Innovative migraine prophylaxis could endanger people with chronic high blood pressure

The neuropeptide αCGRP (α calcitonin gene-related peptide) works in two different ways. It leads to inflammation and dilates the blood vessels right at the release point of the nerve cells, for example in the meninges, which can trigger migraine attacks. However, it has a completely different effect on the heart, as has now been discovered by a team of researchers at the University of Zurich.

26 Nov 2019

Broadly expressed metabolic approach could make sarcoma susceptible to targeted therapies

Soft tissue sarcoma cells stop a key metabolic process which allows them to multiply and spread, and so restarting that process could leave these cancers vulnerable to a variety of treatments.

26 Nov 2019

Targeting molecular mechanisms could be beneficial in diabetic wound care

When our skin is damaged, a whole set of biological processes springs into action to heal the wound. Now, researchers from the VIB-UGent Center for Inflammation Research have shown that one of the molecules involved in this, HMGB1, slows down wound healing.

26 Nov 2019

Sheffield research receives £800k to develop new gene therapy to treat CVD

Cardiac research in Sheffield has received a major boost from the British Heart Foundation in the form of an £800,000 award to develop a new gene therapy to treat cardiovascular disease (CVD).

26 Nov 2019

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences identified a key mechanism for how antiviral immune responses reprogram liver metabolism. Their recent study, which was published in the renowned scientific journal Immunity, investigated the communication between inflammation and liver metabolism during chronic viral infection.

26 Nov 2019

Newly developed personalized vaccine system could delay onset of pancreatic cancer

Researchers from Queen Mary University of London and Zhengzhou University have developed a personalized vaccine system that could ultimately delay the onset of pancreatic cancer. The study provides strong proof-of-concept for the creation of a vaccine for cancer prevention in individuals at high risk of developing this disease and to slow down tumor growth in patients who are affected by it.

26 Nov 2019

New method for correcting hypoxic conditions of the central nervous system

Hypoxia is a key factor that accompanies most brain pathologies, including ischemia and neurodegenerative diseases.

26 Nov 2019

Studying the genomes of hibernating mammals could improve understanding and treatment of obesity

A discovery about mammalian genomes and hibernation could aid understanding and treatment of obesity and metabolic disorders.

26 Nov 2019

Medical Condition News

Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Novel diagnostic method for rapid measurement of celiac disease antibodies

Looking for the source: new routes for allergy treatment

Oligomerix and Feinstein Institutes publish preclinical data of Alzheimer's disease treatment

New wearable sensor for non-invasive gout detection

Skiing associated with reduced risk of vascular dementia but not Alzheimer’s

Aerobic exercise and heart-healthy diet may slow cognitive decline in older adults with CIND

Study reveals novel pathway to target colorectal cancer

Researchers win grants to find innovative treatments for debilitating skin diseases

Kessler Foundation participates in new study to test innovative treatment for hand paralysis

Mcl-1 inhibition blocks cell survival in ER+ breast cancers

Giving a shot of ketamine could help heavy drinkers reduce alcohol intake

Innovative migraine prophylaxis could endanger people with chronic high blood pressure

Broadly expressed metabolic approach could make sarcoma susceptible to targeted therapies

Targeting molecular mechanisms could be beneficial in diabetic wound care

Sheffield research receives £800k to develop new gene therapy to treat CVD

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Newly developed personalized vaccine system could delay onset of pancreatic cancer

New method for correcting hypoxic conditions of the central nervous system

Studying the genomes of hibernating mammals could improve understanding and treatment of obesity

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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