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Heating tumors during CAR T-cell therapy can enhance treatment's success, study suggests

A preclinical study led by scientists at the UCLA Jonsson Comprehensive Cancer suggests that heating solid tumors during CAR T-cell therapy can enhance the treatment's success.

28 Mar 2019

Radiolabeled protein lights up tumor to reveal where cancer drugs are working

Experimenting with mice, Johns Hopkins researchers report they have successfully used positron emission tomography scans to calculate in real time how much of an immunotherapy drug reaches a tumor and what parts of a cancer remain unaffected.

28 Mar 2019

Using gene therapy strategies to rejuvenate aging cells and treat osteoarthritis

Aging is a risk factor for the development of osteoarthritis (OA), a chronic disease characterized by degeneration of articular cartilage leading to pain and physical disability.

28 Mar 2019

Clinical trial examines medicinal cannabis as potential treatment for severe Tourette syndrome

A pioneering clinical trial investigating medicinal cannabis as a potential treatment for people living with severe Tourette syndrome will be conducted by Wesley Medical Research, in Brisbane in Australia, with cannabis supply facilitated by Lambert Initiative for Cannabinoid Therapeutics at University of Sydney.

28 Mar 2019

Garvan researchers develop more accurate method to diagnose cancer subtypes

Developed by researchers at the Garvan Institute of Medical Research, this potential diagnostic method screens a cancer sample for 'fusion genes', estimated to be linked to one in five cancers, and may provide a more accurate snapshot of rearranged DNA found in cancer.

28 Mar 2019

Study describes new muscular disease caused by mutation in myoglobin gene

Researchers of the Bellvitge Biomedical Research Institute led by Dr. Montse Olivé have described in Nature Communications a new muscular disease caused by a mutation in the myoglobin gene.

28 Mar 2019

Study: Lack of physician guidance and fear of side effects are reasons for refusing statins

Despite national guidelines indicating that statins can lower risk of heart attack and stroke, many patients who could benefit do not take them.

28 Mar 2019

New computer program predicts risk of life-threatening arrhythmias

Combining a wealth of information derived from previous studies with data from more than 500 patients, an international team led by researchers from Johns Hopkins has developed a computer-based set of rules that more accurately predicts when patients with a rare heart condition might benefit--or not--from lifesaving implanted defibrillators.

28 Mar 2019

Exercise helps prevent cartilage degradation caused by osteoarthritis, study shows

Exercise helps to prevent the degradation of cartilage caused by osteoarthritis, according to a new study from Queen Mary University of London.

27 Mar 2019

Researchers discover underlying cause of hereditary muscle disease

Researchers at Karolinska Institutet have discovered the underlying cause of a hereditary muscle disease first characterised in a Swedish family in 1980. It proves to be the first identified disease caused by defective myoglobin, the protein that transports oxygen in muscle cells.

27 Mar 2019

Supermarket offers linked to rise in obesity rates

A new report by CRUK reveals that shoppers who look for special offers in the supermarket are more likely to be obese or overweight.

27 Mar 2019

Using connectomics to gain insight into epilepsy

Abnormalities in structural brain networks and how brain regions communicate may underlie a variety of disorders, including epilepsy, which is one focus of a two-part Special Issue on the Brain Connectome in Brain Connectivity, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

27 Mar 2019

Treatment at low-scoring hospitals may increase risk for repeat heart attack and death

Heart attack patients treated at hospitals with low care scores are at greater risk for another heart attack and/or death due to cardiovascular causes, Rutgers researchers found.

27 Mar 2019

Tumor-associated macrophages block activity of chemotherapy drug in pancreatic cancer

A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action, research led by the University of Michigan Rogel Cancer Center found.

27 Mar 2019

Simple parameter can help surgeons in making decisions to treat aneurysms

Aneurysms form as abnormal bulges or balloonings over an artery, and, if ruptured, can lead to serious health complications or even death. Some aneurysms can exist for a long time without rupturing, and the surgery involved in treating aneurysms can be quite risky, so a parameter to help guide surgeons is needed.

27 Mar 2019

Study uncovers large-scale brain patterns and networks that control sleep

An international study headed by researchers from Aarhus University has for the first time uncovered the large-scale brain patterns and networks which control sleep, providing knowledge which in the future may help the large proportion of people who experience problems sleeping.

27 Mar 2019

Encapsulating human beta cells with immune-repelling protein restores glucose metabolism in diabetic mice

Encapsulating human stem-cell-derived beta cells in microcapsules made with a protein that repels key immune cells restored glucose metabolism in diabetic mice and protected the cells from immune system attack, preventing the buildup of inflammatory fibrotic tissue that has plagued previous trials of encapsulated beta cells.

27 Mar 2019

Early treatment of patients with severe aortic stenosis may be better than watch-and-wait approach

Patients with severe aortic stenosis who have no symptoms may benefit more from an aggressive strategy of early valve replacement than from a conservative watch-and-wait approach, according to new research published today online in The Annals of Thoracic Surgery.

27 Mar 2019

People who buy more promotional items have increased chance of being obese

Shoppers whose supermarket trolleys are stacked with food and drink offered on special promotions have more than a 50% increased chance of being obese, according to a Cancer Research UK report published today.

27 Mar 2019

FDA approves new drug to treat adults with relapsing forms of MS

The U.S. Food and Drug Administration today approved Mayzent (siponimod) tablets to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease.

27 Mar 2019

Medical Condition News

Heating tumors during CAR T-cell therapy can enhance treatment's success, study suggests

Radiolabeled protein lights up tumor to reveal where cancer drugs are working

Using gene therapy strategies to rejuvenate aging cells and treat osteoarthritis

Clinical trial examines medicinal cannabis as potential treatment for severe Tourette syndrome

Garvan researchers develop more accurate method to diagnose cancer subtypes

Study describes new muscular disease caused by mutation in myoglobin gene

Study: Lack of physician guidance and fear of side effects are reasons for refusing statins

New computer program predicts risk of life-threatening arrhythmias

Exercise helps prevent cartilage degradation caused by osteoarthritis, study shows

Researchers discover underlying cause of hereditary muscle disease

Supermarket offers linked to rise in obesity rates

Using connectomics to gain insight into epilepsy

Treatment at low-scoring hospitals may increase risk for repeat heart attack and death

Tumor-associated macrophages block activity of chemotherapy drug in pancreatic cancer

Simple parameter can help surgeons in making decisions to treat aneurysms

Study uncovers large-scale brain patterns and networks that control sleep

Encapsulating human beta cells with immune-repelling protein restores glucose metabolism in diabetic mice

Early treatment of patients with severe aortic stenosis may be better than watch-and-wait approach

People who buy more promotional items have increased chance of being obese

FDA approves new drug to treat adults with relapsing forms of MS

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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