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Scientists identify molecular mechanism of muscle stem cell differentiation

Under normal circumstances, adult stem cells reside in muscle tissue, where they can differentiate into a number of different cell types. After an injury (or even a tough workout), muscles are inflamed as cells and molecules flood the area to control damage and begin repairs. When called upon to replace muscle tissue damaged by injury or genetic disease, some muscle stem cells differentiate, becoming new muscle cells, while others make more stem cells. At Sanford-Burnham Medical Research Institute (Sanford-Burnham), a team of scientists led by Pier Lorenzo Puri, M.D., Ph.D., recently uncovered the molecular messengers that translate inflammatory signals into the genetic changes that tell muscle stem cells to differentiate.

11 Oct 2010

Infinity announces preliminary results of IPI-926 Phase 1 study in patients with solid tumors

Infinity Pharmaceuticals, Inc. today announced promising preliminary results from a Phase 1 study of IPI-926, its novel, oral small molecule that targets the Hedgehog pathway.

11 Oct 2010

Research may offer new therapy targets for drug-resistant breast tumors

Researchers at the University of Illinois at Chicago College of Medicine have found how gene expression that may contribute to drug resistance is ramped up in unusual types of breast tumors. Their findings may offer new therapy targets.

11 Oct 2010

Cell Cure to receive equity investment of $7.1 million to develop stem cell-based therapies

BioTime, Inc. Cell Cure Neurosciences Ltd., and Hadasit Bio-Holdings Ltd. jointly announced today that Cell Cure will receive an equity investment of $7.1 million from BioTime, Teva Pharmaceutical Industries Ltd., and Hadasit Bio-Holdings (HBL).

11 Oct 2010

Anti-HER2 antibody-drug conjugate effective as first-line therapy for advanced breast cancer: Research

A new type of breast cancer treatment has shown encouraging activity as a first-line therapy in HER2-positive metastatic disease, researchers reported at the 35th Congress of the European Society for Medical Oncology (ESMO) in Milan, Italy.

11 Oct 2010

Discovery can lead to new approach for treating MS in early stages

A deficiency in one of the immune system's enzymes affects the severity of autoimmune diseases such as MS, and explains why the course of these diseases can vary so much. New findings give an insight into how this enzyme deficiency can be diagnosed, and could lead to new medicines, reveals a thesis from the Sahlgrenska Academy.

11 Oct 2010

Cell Cure, Teva Pharmaceutical enter license option agreement for OpRegen product

BioTime, Inc., Cell Cure Neurosciences Ltd., and Hadasit Bio-Holdings Ltd. jointly announced today that Cell Cure and Teva Pharmaceutical Industries Ltd. have entered into an exclusive license option agreement to develop and commercialize Cell Cure's OpRegen product for the treatment of age-related macular degeneration (AMD).

11 Oct 2010

Japanese MHLW approves CryoLife's BioGlue Surgical Adhesive for aortic dissections

CryoLife, Inc. an implantable biological medical device and cardiovascular tissue processing company, today announced that its BioGlue Surgical Adhesive has received Shonin approval from the Japanese Ministry of Health, Labor and Welfare (MHLW) for use in the repair of aortic dissections.

8 Oct 2010

People involved in ATV crashes are more likely to die from serious trauma: Research

In research that may surprise off-road riding enthusiasts and safety experts, a Johns Hopkins team has found that crashes involving ATVs four-wheeled all-terrain vehicles — are significantly more dangerous than crashes involving two-wheeled off-road motorcycles, such as those used in extreme sports like Motocross.

8 Oct 2010

AFA quarterly magazine features President Obama as guest columnist

President Obama is featured as a guest columnist in the latest issue of the Alzheimer's Foundation of America's (AFA) quarterly magazine for caregivers of individuals with Alzheimer's disease and related illnesses, care ADvantage. In his column, he outlines important provisions in the Affordable Care Act that are relevant to the Alzheimer's community, such as health insurance, drug coverage and long-term care.

8 Oct 2010

Lee National Denim Day event raises $4-$5 million fund for breast cancer

It didn't matter if they were faded, straight leg, boot cut or distressed; hundreds of thousands of people put on jeans with Felicity Huffman to celebrate Lee National Denim Day. The event has become one of the largest single-day fundraisers for breast cancer, and through $5 donations, has raised an estimated $4-$5 million for the Women's Cancer Programs of the Entertainment Industry Foundation (EIF), bringing the 15-year total to nearly $85 million.

8 Oct 2010

Experts meet on ESMO Congress to bring new hope to cancer patients

"A congress of records," is how Professor David J. Kerr, President of the European Society for Medical Oncology described the 35th ESMO Congress, at the opening press conference for the biggest medical oncology event in Europe. "We have had record numbers of submitted and accepted abstracts and are expecting a record number of attendees." The ESMO meeting brings together cancer specialists, patients, industry representatives and members of the media. The 35th ESMO Congress takes place at Fiera Milano City, in Milan, Italy, from 8 to 12 October 2010.

8 Oct 2010

Progress made with enactment of ADA, but people still face challenges: Disability and Health Journal

In recognition of the 20th anniversary of the enactment of the Americans with Disabilities Act, the October issue of Disability and Health Journal has brought together a series of articles to examine whether the ADA has in fact improved the health of people with disabilities. Areas of progress are identified, most notably acknowledging physical barriers and need for better staff training and communication about and with people with disabilities.

8 Oct 2010

Portrait painting may help children with craniofacial problems

A group of artists, young people and medical experts are involved in a groundbreaking project at The Children's Hospital of Philadelphia that uses the intimate process of portrait painting to help children and young people with craniofacial problems see themselves in a different light.

8 Oct 2010

Mouse study may help develop new therapies for spinal cord injury

Researchers at Karolinska Institutet have shown how stem cells, together with other cells, repair damaged tissue in the mouse spinal cord. The results are of potential significance to the development of therapies for spinal cord injury.

8 Oct 2010

Biologists determine three-dimensional structure of molecule involved in HIV, cancer

In a technical tour de force, structural biologists funded by the National Institutes of Health have determined the three-dimensional structure of a molecule involved in HIV infection and in many forms of cancer. The high-resolution structure sheds light on how the molecule functions and could point to ways to control its activity, potentially locking out HIV and stalling cancer's spread.

8 Oct 2010

SRA International receives award of task order to continue support for TCGA

SRA International, Inc., a leading provider of technology and strategic consulting services and solutions to government organizations and commercial clients, today announced the award of a task order as a contractor to the National Institutes of Health to continue bioinformatics support of the Data Coordinating Center for The Cancer Genome Atlas.

8 Oct 2010

Presbyterian Hospital collaborates with New York Center for Autism to establish Institute for Brain Development

NewYork-Presbyterian Hospital, along with its affiliated medical schools Columbia University College of Physicians and Surgeons and Weill Cornell Medical College, announced its collaboration with the New York Center for Autism to establish the Institute for Brain Development, a comprehensive, state-of-the-art institute dedicated to addressing the pressing clinical needs of individuals living with autism spectrum disorders and other developmental disorders of the brain, across their lifespan.

8 Oct 2010

Cincinnati Children's Hospital Medical Center named Centers of Excellence for Molecular Hematology

Cincinnati Children's Hospital Medical Center has been named one of five national Centers of Excellence for Molecular Hematology to find new gene and cell therapies for inherited diseases affecting blood cells.

8 Oct 2010

Survey shows obstetricians, gynecologists unfamiliar with Chagas' disease

According to recent survey results published in the October issue of The American Journal of Tropical Medicine and Hygiene, obstetricians and gynecologists in the United States are unfamiliar with Chagas' disease, a condition that affects an estimated 300,000 people in the United States and can cause serious cardiovascular and digestive complications.

8 Oct 2010

Medical Condition News

Scientists identify molecular mechanism of muscle stem cell differentiation

Infinity announces preliminary results of IPI-926 Phase 1 study in patients with solid tumors

Research may offer new therapy targets for drug-resistant breast tumors

Cell Cure to receive equity investment of $7.1 million to develop stem cell-based therapies

Anti-HER2 antibody-drug conjugate effective as first-line therapy for advanced breast cancer: Research

Discovery can lead to new approach for treating MS in early stages

Cell Cure, Teva Pharmaceutical enter license option agreement for OpRegen product

Japanese MHLW approves CryoLife's BioGlue Surgical Adhesive for aortic dissections

People involved in ATV crashes are more likely to die from serious trauma: Research

AFA quarterly magazine features President Obama as guest columnist

Lee National Denim Day event raises $4-$5 million fund for breast cancer

Experts meet on ESMO Congress to bring new hope to cancer patients

Progress made with enactment of ADA, but people still face challenges: Disability and Health Journal

Portrait painting may help children with craniofacial problems

Mouse study may help develop new therapies for spinal cord injury

Biologists determine three-dimensional structure of molecule involved in HIV, cancer

SRA International receives award of task order to continue support for TCGA

Presbyterian Hospital collaborates with New York Center for Autism to establish Institute for Brain Development

Cincinnati Children's Hospital Medical Center named Centers of Excellence for Molecular Hematology

Survey shows obstetricians, gynecologists unfamiliar with Chagas' disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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