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Cortisol hormone controls bile acid recycling process

Nature sees to it that we do not have "too much choler" in our body. A delicately equilibrated regulation system ensures that there is always exactly the right amount of bile in the gallbladder. When we are hungry, our body releases a hormone called cortisol, which is a glucocorticoid. Hepatic cells receive this hormone signal through their cortisol receptors and respond by filling the gallbladder with bile in preparation of the imminent food intake.

8 Jul 2011

New NCCN Clinical Practice Guideline on Malignant Pleural Mesothelioma

The National Comprehensive Cancer Network (NCCN), with the support of the NCCN Foundation, announces the latest addition to the library of NCCN Guidelines for Patients, the NCCN Guidelines for Patients: Malignant Pleural Mesothelioma.

8 Jul 2011

Exenatide tQT clinical trial meets pre-specified primary endpoint

Amylin Pharmaceuticals, Inc., Eli Lilly and Company and Alkermes, Inc. today announced results from a thorough QT (tQT) study that assessed the potential of exenatide to increase the QT interval across a wide range of plasma concentrations.

8 Jul 2011

PDF announces $1M for 11 novel Parkinson's research projects

The Parkinson's Disease Foundation (PDF) is pleased to announce awards totaling more than $1 million for 11 novel investigator-initiated research projects designed to understand the causes of and find a cure for Parkinson's disease.

8 Jul 2011

Roche, CPRIT partner to advance cancer research projects in Texas

The Cancer Prevention and Research Institute of Texas (CPRIT) today announced a strategic partnership agreement with the Swiss-based healthcare company Roche to accelerate the development of promising oncology-related cancer research projects in Texas.

8 Jul 2011

Viewpoints: Debt talks 'opportunity'; NY Times on cancer drugs; Calif. insurance rate regs

For months, we have known that no plan will succeed if it just slashes programs such as Medicare or imposes big hikes in tax rates. We've known that we need a plan that eliminates at least $4 trillion in debt over the next decade, slows the growth in entitlement programs and raises new revenue through tax reform.

8 Jul 2011

Tulane University receives NIH grant to examine oil spill effects on women's health

The NIH's National Institute of Environmental Health Sciences has awarded Tulane University School of Public Health and Tropical Medicine $6.5 million for a five-year study exploring the potential health impacts of the Deepwater Horizon disaster on pregnant women and women of reproductive age living in Louisiana's coastal parishes.

8 Jul 2011

Researchers identify cellular origin of malignant glioma

Using a mouse genetic system co-developed by researchers at the University of Oregon and Stanford University, a research team led by UO biologist Hui Zong has isolated the cellular origin for malignant glioma, a deadly human brain cancer.

8 Jul 2011

Enrollment commences in InterMune's Esbriet Phase 3 study for IPF

InterMune today announced that patient enrollment has begun in ASCEND, a new Phase 3 study of pirfenidone for patients who suffer from idiopathic pulmonary fibrosis.

8 Jul 2011

Half-matched transplants widen donor pool for leukemia and lymphoma

Identifying a suitable donor for leukemia and lymphoma patients who need bone marrow transplants may be far easier now that results of two clinical trials show transplant results with half-matched bone marrow or umbilical cord blood are comparable to fully matched tissue, thanks in large part to the availability of effective antirejection drugs and special post-transplant chemotherapy. The finding means that nearly all patients in need of a transplant can find donors, according to Johns Hopkins scientists who participated in the trials.

7 Jul 2011

Gender may increase risk of cartilage lesions in ACL knee injury

Gender may be associated with an increased risk of cartilage lesions in anterior cruciate ligament (ACL) injured knees, according to research being presented at the American Orthopaedic Society for Sports Medicine's Annual Meeting in San Diego.

7 Jul 2011

Study finds large state disparities in progress against colorectal cancer mortality rates

Improvements in colorectal cancer mortality rates are concentrated in the northern part of the United States, while southern states continue to fall behind, according to a report in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

7 Jul 2011

Researchers use AFM to characterize ovarian cell structure for cancer diagnosis

Using ovarian surface epithelial cells from mice, researchers from Virginia Tech have released findings from a study that they believe will help in cancer risk assessment, cancer diagnosis, and treatment efficiency in a technical journal: Nanomedicine.

7 Jul 2011

Experiment to protect astronauts from bone loss during space travel

Astronauts lose a significant amount of bone mass during space travel and with long duration flights there is concern that this bone loss could lead to an increased risk of fractures.

7 Jul 2011

Researchers find new molecule that controls pain sensitivity from UVB irradiation

Researchers at King's College London have found a molecule in the body which controls sensitivity to pain from UVB irradiation, identifying it as a new target for medicines to treat pain caused by other common inflammatory conditions such as arthritis.

7 Jul 2011

Cultural, gender and ethnic stereotypes can distort treatment of Parkinson's

Cultural, ethnic and gender stereotypes can significantly distort clinical judgments about "facially masked" patients with Parkinson's disease, according to a newly published study from researchers at Tufts University, Brandeis University and the National Cheng Kung University in Taiwan.

7 Jul 2011

Study provides information about trends in obesity, public health implications

Researchers out of Arizona State University recently published an article in the American Journal of Public Health titled "Shared Norms and Their Explanation for the Social Clustering of Obesity". It looked at why obesity seems to be common in some families and groups of friends.

7 Jul 2011

Study finds link between genetic variation and cetuximab rectal cancer therapy

team of researchers led by Keck School of Medicine of the University of Southern California (USC) oncologist Heinz-Josef Lenz, M.D., has identified a genetic marker that may predict which patients with rectal cancer can be cured by certain chemotherapies when combined with surgery.

7 Jul 2011

Progress in reducing colorectal cancer mortality rates varies across U.S. states

Progress in reducing colorectal cancer (CRC) mortality rates varies significantly across states, with rates in the Northeast showing the most progress and those in the South showing the least progress, according to a new study.

7 Jul 2011

Medicare coverage, pricey cancer drugs and the 'rationing' issue

As health care costs play an ever-increasing role in Washington's budget drama, Medicare officials announced last week they will continue to pay for two extremely expensive cancer treatments despite lingering questions about their effectiveness. At a cost of about $88,000 per year, the cancer-fighting Avastin will still be available to eligible senior citizens for breast cancer treatment.

7 Jul 2011