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Researchers discover gene that contributes to depression

Yale University researchers have found a gene that seems to be a key contributor to the onset of depression and is a promising target for a new class of antidepressants, they report Oct. 17 in the journal Nature Medicine.

18 Oct 2010

Neogenix to present NPC-1C antibody data at ASCO Annual Meeting

Neogenix Oncology, Inc. announced today that it will present data from its new serum biomarker ELISA utilizing its NPC-1C antibody for patients with colorectal and pancreatic cancers. Results from the study will be presented at the American Society of Clinical Oncology (ASCO)-NCI-EORTC Annual Meeting on Molecular Makers in Cancer, to be held in Hollywood, Florida from October 18-20, 2010.

18 Oct 2010

ACG meeting to exhibit Cimzia data for Crohn's disease treatment

Studies and analyses of the Crohn's disease (CD) treatment Cimzia (certolizumab pegol) will be exhibited at the 2010 Annual Scientific Meeting of the American College of Gastroenterology, taking place in San Antonio from October 15 – 20.

18 Oct 2010

Research on gut flora may lead to new treatment strategies for atherosclerosis

New findings suggesting that bacteria in the mouth and/or intestine can affect the the outcome pathogenesis of atherosclerosis and lead to new treatment strategies, reveals research from the University of Gothenburg, Sweden.

18 Oct 2010

Biogen, Elan announce clinical utility data of two-step ELISA to detect anti-JCV antibodies

Biogen Idec and Elan Corporation, plc today announced data further supporting the potential clinical utility of an investigational assay that detects anti-JC virus (JCV) antibodies in human plasma or serum.

18 Oct 2010

Researchers report progress on two eye disease challenges at AAO-MEACO 2010 Joint Meeting

At the American Academy of Ophthalmology (AAO) Middle East-Africa Council of Ophthalmology (MEACO) Joint Meeting today, researchers report progress on two top eye disease challenges treating advanced "dry" age-related macular degeneration, and preventing blindness in people with diabetes.

18 Oct 2010

Researchers discover blocking beta-arrestin 1 protein can reduce severity of heart failure

A Nova Southeastern University (NSU) researcher has announced a breakthrough discovery to block a protein that can contribute to heart failure. His discovery will appear in an upcoming issue of the prestigious medical journal, the Journal of the American College of Cardiology.

18 Oct 2010

Researchers study anti-inflammatory effects of food on healthy individuals

For the first time researchers have found out what effect multiple, rather than just single, foods with anti-inflammatory effects have on healthy individuals. The results of a diet study show that bad cholesterol was reduced by 33 per cent, blood lipids by 14 per cent, blood pressure by 8 per cent and a risk marker for blood clots by 26 per cent. A marker of inflammation in the body was also greatly reduced, while memory and cognitive function were improved.

18 Oct 2010

Small changes in weight can make huge difference in BP for overweight children

Small changes in weight can make bigger differences in the blood pressure for overweight children, compared to those at normal weight, according to a new study. Researchers tracked blood pressure, height and weight of 1,113 children over time, with the longest follow-up exceeding 10 years. They then compared the children's body mass index (BMI, a measure of body weight) to national charts adjusted for age, sex and height. Kids with BMIs in the 85th percentile or higher are considered overweight.

18 Oct 2010

Nektar presents NKTR-181 preclinical data at ASA 2010 Annual Meeting

Nektar Therapeutics today presented new preclinical data demonstrating that NKTR-181, a mu-opioid analgesic with a novel molecular structure, dramatically reduces abuse liability while providing analgesia comparable to oxycodone and morphine.

18 Oct 2010

Tocotrienols can help reduce triglyceride levels

Scientists from Singapore found that tocotrienols, which are members of the Vitamin E family, are effective in lowering the levels of triglyceride, a form of fat in the blood. High levels of triglyceride are closely linked to an increased risk of cardiovascular and metabolic diseases.

18 Oct 2010

PTC announces ataluren Phase 2b efficacy data at International Congress

PTC Therapeutics, Inc. today announced that final analyses of Phase 2b efficacy data suggest the investigational new drug ataluren slowed the loss of walking ability in patients with nonsense mutation dystrophinopathy, a disease continuum comprising Duchenne and Becker muscular dystrophy (nmDBMD). These data were presented at the International Congress of the World Muscle Society in Kumamoto, Japan and will be the basis of interactions with the U.S. Food and Drug Administration (FDA) and national regulatory authorities in Europe in the fourth quarter of 2010.

18 Oct 2010

Six-year data of reinforces efficacy and safety of Reclast injection in postmenopausal women with osteoporosis

Novartis announced today that new six-year data reinforce the long-term efficacy and safety profile of once-yearly Reclast (zoledronic acid) injection in postmenopausal women with osteoporosis. The study of more than 1,200 women was presented this weekend at the annual meeting of the American Society for Bone and Mineral Research (ASBMR) in Toronto, ON, Canada.

18 Oct 2010

FDA approves ISTA's sNDA for BROMDAY ophthalmic anti-inflammatory drug

ISTA Pharmaceuticals, Inc. today announced the U.S. Food and Drug Administration (FDA) has approved the Company's supplemental New Drug Application (sNDA) for BROMDAY (bromfenac ophthalmic solution) 0.09% as a once-daily prescription eye drop for the treatment of postoperative inflammation and reduction of ocular pain in patients who have undergone cataract extraction.

18 Oct 2010

Researchers identify genes that predict early menopause

The first research from the Breakthrough Generations Study could lead to a test to predict a woman's reproductive lifespan. The findings, published today in Human Molecular Genetics, could have considerable impact on women in the UK and other western countries, where many start having children at a later age. Early menopause affects one in 20 UK women.

18 Oct 2010

Whooping cough cases increase

Whooping cough (Pertussis) a dreaded childhood disease that is vaccine preventable is back. After two doctors in Adelaide tested positive to whooping cough, nearly a 100 adults and children are being given precautionary antibiotics.

18 Oct 2010

2010 AAO-MEACO meeting focuses on genetic medicine

Genetic medicine is the focus of two presentations at today's Scientific Program of the 2010 American Academy of Ophthalmology (AAO) Middle East-Africa Council of Ophthalmology (MEACO) Joint Meeting. The AAO-MEACO meeting is in session October 16 through 19 at McCormick Place, Chicago. It is the largest, most comprehensive ophthalmic education conference in the world.

18 Oct 2010

Diagnosis is vital to differentiae Lewy body dementia and Parkinson's disease dementia

Alzheimer's disease is not the only type of dementia. Two particular forms are dementia with Lewy bodies and Parkinson's disease dementia. In both forms, the diagnosis is of vital importance because the treatment for these dementias differs from that for Alzheimer's dementia, as Brit Mollenhauer and co-authors explain in the dementia theme issue of Deutsches -rzteblatt International.

18 Oct 2010

TOPS program helps in losing weight: Study

In the battle against obesity, new research has found that it may not be necessary to spend a lot on a weight loss program when cheaper, nonprofit alternatives may work just as well.

18 Oct 2010

Teva Pharmaceutical announces new data from PreCISe study

Teva Pharmaceutical Industries Ltd. today announced new data from the five-year extension of the PreCISe study demonstrating that earlier initiation of treatment with Copaxone (glatiramer acetate injection) in patients presenting with first signs of multiple sclerosis (MS), provided greater effects in delaying conversion to clinically definite MS (CDMS) compared to later treatment initiation after diagnosis of CDMS or after three years on the study.

18 Oct 2010