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Results of study evaluating potential inhibitory effects of PPIs on Plavix presented at ACC 2011

Takeda Pharmaceuticals North America, Inc. announced the presentation of new study results, which evaluated the potential inhibitory effects of certain proton pump inhibitors (PPIs) on Plavix (clopidogrel bisulfate). The results showed that in healthy subjects, clopidogrel's active metabolite and inhibition of platelet function were reduced less by the co-administration of clopidogrel with dexlansoprazole or lansoprazole, rather than esomeprazole.

6 Apr 2011

ICD therapy can improve ischemic cardiomyopathy survival rates

Most patients with ischemic cardiomyopathy and dilated cardiomyopathy who have an implantable cardioverter-defibrillator now live more than seven years and those ICD patients with hereditary heart disease can live for decades, based on a scientific paper that will be presented at the American College of Cardiology Scientific Sessions in New Orleans, April 1-3.

6 Apr 2011

Roswell Park Cancer Institute selected to be part of Cancer Immunotherapy Trials Network

Roswell Park Cancer Institute (RPCI) is one of 27 North American research institutions that have been selected to be part of the Cancer Immunotherapy Trials Network (CITN), a new immunotherapy initiative funded by the National Cancer Institute (NCI). Kunle Odunsi, MD, PhD, FRCOG, FACOG, Director of the Center for Immunotherapy and Chair of Gynecologic Oncology at RPCI, will serve as Principal Investigator of the Institute's role in this collaborative investigative effort.

6 Apr 2011

Researchers develop new stroke rehabilitation devices

Devices which could be used to rehabilitate the arms and hands of people who have experienced a stroke have been developed by researchers at the University of Southampton.

6 Apr 2011

Pancreatic Cancer Action Network, AACR honor NYU School of Medicine's scientist with Fellowship

NYU School of Medicine's Cosimo Commisso, PhD, a postdoctoral fellow in the Department of Biochemistry, is the 2011 recipient of The Pancreatic Cancer Action Network-American Association for Cancer Research Fellowship, a one-year grant designed to support pancreatic cancer research.

6 Apr 2011

SWHR roundtable to examine sex differences in Alzheimer's disease

At the Women's Health 2011: 19th Annual Conference plenary session, A Wake Up Call to Clinicians: Alzheimer's and Early Diagnosis, Geoffrey Beene Foundation President, Meryl Comer announced the Society for Women's Health Research's upcoming one-day Alzheimer's roundtable, exploring sex differences in this increasingly prevalent disease.

6 Apr 2011

Record number of medicines for various cancers in clinical trials

A record 887 medicines for various of cancers are in clinical trials or awaiting Food and Drug Administration (FDA) review—well over double the number in the pipeline just six years ago, according to a report unveiled today by the Pharmaceutical Research and Manufacturers of America (PhRMA).

6 Apr 2011

Celldex presents CDX-1127 preclinical data against cancer at AACR meeting

Celldex Therapeutics, Inc. today announced that new data on its preclinical therapeutic antibody program, CDX-1127, is being presented in a poster presentation at the 2011 American Association for Cancer Research 102nd Annual Meeting in Orlando, FL.

6 Apr 2011

Specific lipids in tumours linked to cancer progression and patient survival

Activation of lipid metabolism is an early event in carcinogenesis and a central hallmark of many cancers. However, the precise molecular composition of lipids in tumours remains generally poorly characterised. Scientists from VTT Technical Research Centre of Finland and the Charité Hospital have found lipids in tumours which are associated with cancer progression.

6 Apr 2011

Work, social and family disability affect 50% of patients with bipolar disorder

Such was the conclusion obtained in a study conducted at the University of Granada that was recently awarded a prize in the IV Spain-Portugal Meeting on Therapeutical Adherence held in Oporto.

6 Apr 2011

Aeterna Zentaris presents AEZS-131 data against cancer at AACR meeting

Aeterna Zentaris Inc. today announced that a poster on its highly selective Erk 1/2 inhibitor anticancer compound, AEZS-131, was presented at the 102nd annual meeting of the American Association for Cancer Research currently held at the Orange County Convention Center in Orlando, Florida.

6 Apr 2011

Heart patients share perspectives on deactivation, donation and reuse of ICD devices

Each year, more than 100,000 patients in the U.S. undergo implantation of a new implantable cardioverter defibrillator (ICD) for heart rhythm abnormalities. This number constitutes a 20-fold increase over the last 15 years. Current medical guidelines advocate discussion of end of life care of these medical devices, including deactivation, but many patients may not understand their options.

6 Apr 2011

Aid groups respond to escalating violence in Cote d'Ivoire

"Aid organizations are warning of an impending humanitarian crisis for tens of thousands of refugees who have arrived in Liberia after fleeing violence" in Cote d'Ivoire, CNN reports.

6 Apr 2011

AMPK suppression and SREBP activation are root cause of fatty liver and hyperlipidemia in type 2 diabetes

Researchers from Boston University School of Medicine, including Yu Li, PhD, and other colleagues, have demonstrated that a nutrient sensing pathway is involved in the disruption of cellular lipid homeostasis in obese and insulin resistant mice fed a diet high in fat and sucrose.

6 Apr 2011

Early Intensive Behavioural Intervention in autism continues to be questioned in Quebec

Early Intensive Behavioural Intervention, the most highly recommended, comprehensively researched and universally recognized treatment for autism, continues to be questioned, underfunded and ultimately threatened - but only in Quebec.

6 Apr 2011

J&JPRD announces rivaroxaban Phase 3 trial results against venous thromboembolism

Johnson & Johnson Pharmaceutical Research & Development, L.L.C., today announced results from the MAGELLAN Phase 3 trial evaluating the investigational oral anticoagulant rivaroxaban for the prevention of venous thromboembolism in hospitalized patients with acute medical illnesses.

6 Apr 2011

Socioeconomic factors still influence autism diagnosis

While there is an increasing equality in terms of the likelihood that children from communities and families across the socioeconomic spectrum will be diagnosed with autism, a new study finds that such factors still influence the chance of an autism diagnosis, though to a much lesser extent than they did at the height of rising prevalence.

6 Apr 2011

Soy food does not increase risk of recurrence or death among breast cancer survivors

Soy food consumption did not increase the risk of cancer recurrence or death among survivors of breast cancer, according to the results of a study presented at the AACR 102nd Annual Meeting 2011, held April 2-6.

6 Apr 2011

Novartis' TOBI Podhaler receives Health Canada NOC for Pa treatment in CF patients

Novartis Canada announced today that it has received Health Canada Notice of Compliance for TOBI Podhaler, a fast and convenient inhaled therapy for cystic fibrosis patients aged six and over.

6 Apr 2011

Keryx KRX-0401 data in colorectal cancer, multiple myeloma presented at AACR meeting

Keryx Biopharmaceuticals, Inc. today announced that two posters on KRX-0401 were presented at the 102nd annual meeting of the American Association for Cancer Research currently ongoing at the Orange County Convention Center in Orlando, Florida. Perifosine, the Company's novel, potentially first-in-class, oral anti-cancer agent that inhibits Akt activation in the phosphoinositide 3-kinase pathway, is currently in Phase 3 clinical trials for refractory advanced colorectal cancer and multiple myeloma.

6 Apr 2011

Medical Condition News

Results of study evaluating potential inhibitory effects of PPIs on Plavix presented at ACC 2011

ICD therapy can improve ischemic cardiomyopathy survival rates

Roswell Park Cancer Institute selected to be part of Cancer Immunotherapy Trials Network

Researchers develop new stroke rehabilitation devices

Pancreatic Cancer Action Network, AACR honor NYU School of Medicine's scientist with Fellowship

SWHR roundtable to examine sex differences in Alzheimer's disease

Record number of medicines for various cancers in clinical trials

Celldex presents CDX-1127 preclinical data against cancer at AACR meeting

Specific lipids in tumours linked to cancer progression and patient survival

Work, social and family disability affect 50% of patients with bipolar disorder

Aeterna Zentaris presents AEZS-131 data against cancer at AACR meeting

Heart patients share perspectives on deactivation, donation and reuse of ICD devices

Aid groups respond to escalating violence in Cote d'Ivoire

AMPK suppression and SREBP activation are root cause of fatty liver and hyperlipidemia in type 2 diabetes

Early Intensive Behavioural Intervention in autism continues to be questioned in Quebec

J&JPRD announces rivaroxaban Phase 3 trial results against venous thromboembolism

Socioeconomic factors still influence autism diagnosis

Soy food does not increase risk of recurrence or death among breast cancer survivors

Novartis' TOBI Podhaler receives Health Canada NOC for Pa treatment in CF patients

Keryx KRX-0401 data in colorectal cancer, multiple myeloma presented at AACR meeting

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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