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High coffee intake associated with cardiovascular disease mortality in hypertensive individuals

A study published in the Journal of the American Heart Association describes that excessive consumption of coffee can increase the risk of cardiovascular disease-related mortality in individuals with severe hypertension.

23 Dec 2022

Japanese study reveals increase in incidence rates of renal replacement therapy attributed to nephrosclerosis

A new Japanese study reveals that the age-standardized incidence rates of end-stage kidney disease (ESKD) requiring renal replacement therapy (RRT) due to chronic glomerulonephritis and diabetic nephropathy has decreased, while rates due to nephrosclerosis have increased considerably between 2006 and 2020.

23 Dec 2022

Study compares two non-invasive interventions for spine pain on disability and health care spending

Pain in the back or the neck is extremely common and accounts for more healthcare spending than any other health condition.

23 Dec 2022

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

In order to treat patients with diabetes in the best possible way it is necessary to understand the disease mechanism. MODY type 3 (MODY3) is a monogenic hereditary form of diabetes, that is caused by a genetic defect in the HNF1A gene.

22 Dec 2022

Plasma GH is a biomarker candidate for predicting outcomes in advanced HCC patients treated with Atezo/Bev

A new research paper was published in Oncotarget's Volume 13 on December 6, 2022, entitled, "Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced hepatocellular carcinoma patients."

22 Dec 2022

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

A recent Nature Cancer study documented that individuals with B cell lymphomas (LY) and multiple myeloma (MM) developed potent infection neutralization capabilities against several SARS-CoV-2 variants of concern (VoCs).

22 Dec 2022

Using the gut microbiome to understand and treat respiratory diseases

Researchers review the role of the gut microbiome in certain respiratory diseases.

22 Dec 2022

Microscopy techniques reveal a trail of destruction in bone collagen caused by high energy X-rays

A team of medical researchers at Charité has analyzed damage by focused high energetic X-rays in bone samples from fish and mammals at BESSY II.

22 Dec 2022

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers.

22 Dec 2022

Study links NAFLD with brain deterioration and identifies a potential therapeutic target

People with liver disease caused by eating too much sugar and fat could be at increased risk of developing serious neurological conditions like depression or dementia.

22 Dec 2022

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

The medical community has never researched the simultaneous impact of post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and genetic risk factors in a large cohort … until now.

22 Dec 2022

Extracellular vesicles enhance cancer immunotherapy

Nano-sized membrane bubbles known as extracellular vesicles activate the immune system in mice and seem to render their tumors sensitive to a type of immunotherapy drug called a checkpoint inhibitor.

22 Dec 2022

Study could pave the way for new drug to treat hand osteoarthritis

A new study, published in Science Translational Medicine by researchers at the University of Oxford has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models.

22 Dec 2022

Botox treatment may lessen anxiety

Botox, or Botulinum toxin, a medication derived from a bacterial toxin, is commonly injected to ease wrinkles, migraines, muscle spasms, excessive sweating and incontinence.

22 Dec 2022

Elite male football players who played in the 1960s and later have lower risk of alcohol disorders

Elite male football players have a lower risk of alcohol and drug related disorders than men from the general population, but this protective effect was seen only for those who first played in the 1960s and later, not for players from earlier eras, finds a study in the Christmas issue of The BMJ.

22 Dec 2022

Physicians reveal main risk factors for sudden death from a colloid cyst

RUDN University physicians investigated known cases of sudden death from a colloid cyst. After analyzing the data, the authors named the main risk factors and told what to look for. The results are published in the Journal of Clinical Neuroscience.

22 Dec 2022

Impact of epigenetics on the clinical management of cancer patients

Dr. Manel Esteller and Dr. Verónica Dávalos, researchers at the Josep Carreras Leukaemia Research Institute, describe in a new article the impact of epigenetics on cancer treatment and how it has become a crucial tool to improve early detection, predict disease progression and become a target for new treatments.

22 Dec 2022

Study increases understanding of the genetic architecture of dementia risk in African ancestry populations

In the largest-ever genetic study of dementia in people of African ancestry, VA researchers identified several genetic risks different from those seen in people of European ancestry.

22 Dec 2022

Study helps understand why some people have persistent smell loss after COVID-19 infection

The reason some people fail to recover their sense of smell after COVID-19 is linked to an ongoing immune assault on olfactory nerve cells and an associated decline in the number of those cells, a team of scientists led by Duke Health report.

21 Dec 2022

Sotorasib achieves meaningful anticancer activity in patients with KRAS G12C-mutated metastatic pancreatic cancer

In the Phase I/II CodeBreaK 100 trial, the KRAS G12C inhibitor sotorasib achieved meaningful anticancer activity with an acceptable safety profile in heavily pretreated patients with KRAS G12C-mutated metastatic pancreatic cancer, according to researchers at The University of Texas MD Anderson Cancer Center.

21 Dec 2022

Medical Condition News

High coffee intake associated with cardiovascular disease mortality in hypertensive individuals

Japanese study reveals increase in incidence rates of renal replacement therapy attributed to nephrosclerosis

Study compares two non-invasive interventions for spine pain on disability and health care spending

Researchers identify a new pathogenic mechanism for diabetes onset in MODY3

Plasma GH is a biomarker candidate for predicting outcomes in advanced HCC patients treated with Atezo/Bev

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

Using the gut microbiome to understand and treat respiratory diseases

Microscopy techniques reveal a trail of destruction in bone collagen caused by high energy X-rays

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

Study links NAFLD with brain deterioration and identifies a potential therapeutic target

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

Extracellular vesicles enhance cancer immunotherapy

Study could pave the way for new drug to treat hand osteoarthritis

Botox treatment may lessen anxiety

Elite male football players who played in the 1960s and later have lower risk of alcohol disorders

Physicians reveal main risk factors for sudden death from a colloid cyst

Impact of epigenetics on the clinical management of cancer patients

Study increases understanding of the genetic architecture of dementia risk in African ancestry populations

Study helps understand why some people have persistent smell loss after COVID-19 infection

Sotorasib achieves meaningful anticancer activity in patients with KRAS G12C-mutated metastatic pancreatic cancer

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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