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Novel immunotherapy offers a promising new strategy to fight hard-to-treat cancers

Scientists at UC San Francisco have engineered T cells to produce a potent anti-cancer cytokine, but only when they encounter tumor cells.

16 Dec 2022

Study shows how a specific gut microbe-generated byproduct is linked to heart failure risk

New research at Cleveland Clinic expands the link between what we eat and how the gut microbiome impacts our susceptibility to develop different diseases – in this case, how a specific gut microbe-generated byproduct is linked to heart failure risk.

16 Dec 2022

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15) —a protein whose expression increases in response to cellular stress— to present its antidiabetic effects.

16 Dec 2022

NEJM study shows hidden genetic anomaly behind common late-onset cerebellar ataxia

Researchers at the University of Miami Miller School of Medicine, McGill University and other institutions have found that a well-concealed genetic variation in the gene FGF14, called a DNA tandem repeat expansion, causes a common form of late-onset cerebellar ataxia, a brain disorder that interferes with coordinated movement.

16 Dec 2022

Adult children four times more likely to be estranged from fathers than mothers

Adult children are over four times more likely to be estranged from their fathers than their mothers, a new long-term national study found.

16 Dec 2022

Structured analysis of personal criteria can make people more likely to save lives

When a person is facing a life-or-death decision, considering how certain aspects of the situation should affect their choice can make them more likely to save lives – according to new research published in Social Psychological and Personality Science.

16 Dec 2022

Landmark population health study could pave the way for better tools to fight chronic diseases in Asian populations

The Lee Kong Chian School of Medicine at Nanyang Technological University, Singapore, in collaboration with other healthcare institutions here, has embarked on a landmark comprehensive population health study of 100,000 Singaporeans over a few decades to identify the social, environmental, lifestyle, and genetic factors associated with diseases prevalent in Singapore, such as diabetes, hypertension, and cancer.

16 Dec 2022

People of all age groups benefit more from COVID-19 vaccines than natural immunity, real-world study finds

In one of the first large, real-world studies comparing the effectiveness of COVID-19 vaccines versus natural immunity in protecting against death, hospitalizations and emergency department (ED) visits for any cause, including COVID, research-scientists from Regenstrief Institute, Indiana University School of Medicine and Vanderbilt University Medical Center report that people of all age groups benefited significantly more from vaccination than natural immunity acquired from a previous COVID infection.

16 Dec 2022

New support for a serotonin deficit in depression

Since the 1960s, researchers have postulated that major depression stems from disruptions in the serotonin neurotransmitter system, but the evidence for that idea, though plentiful, was indirect.

16 Dec 2022

ACS' new program associated with increased efficiency in treating pediatric trauma patients

An American College of Surgeons quality improvement program designed to specifically improve pediatric surgical care in U.S. hospitals reduced surgical wait times, cut hospital stays by more than a day, and significantly curbed narcotics use in children who had major operations for traumatic femur fractures, according to research published online as an "article in press" in the Journal of the American College of Surgeons.

16 Dec 2022

High performing primary care practices for patients with diabetes during the pandemic

Published in PLOS ONE, University of Minnesota Medical School researchers explored how high performing primary care practices organized care for patients with diabetes during the first months of the COVID-19 pandemic.

16 Dec 2022

Walnut consumption has positive effects on stressed university students

Stressed university students might want to add walnuts to their daily diet in the weeks leading up to their next exam.

16 Dec 2022

Study provides new insights into the pathology of LATE

Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer's disease or AD (and sometimes co-exists with it), but LATE is a different condition, with its own risks and causes.

16 Dec 2022

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

The Lupus Research Alliance (LRA) proudly announces the two outstanding recipients of the 2022 Distinguished Innovator Award (DIA): Hongbo Chi, PhD, and Joseph Craft, MD.

16 Dec 2022

Adding Gli1+ cells could regenerate the enthesis after rotator cuff surgery

In the annals of shoulder surgery, NFL quarterback Drew Brees is an anomaly. In 2005, Brees was tackled and the rotator cuff tendon in his throwing shoulder was severely torn, a potentially career-ending injury.

16 Dec 2022

Outpatient clinic visits with a nephrologist associated with lower risk of mortality in patients with acute kidney injury

Outpatient clinic visits with a nephrologist and attention to kidney complications and cardiovascular disease were associated with 29% lower risk of mortality compared to standard of care in patients with AKI during recent hospitalization.

16 Dec 2022

Study: People with cluster headaches may be more likely to have other medical conditions

People with cluster headaches may be more than three times more likely to have other medical conditions such as heart disease, mental disorders and other neurologic diseases, according to a study published in the December 14, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

16 Dec 2022

Researchers report the development of robust candidate single immunization PNP hydrogel COVID vaccines

Researchers developed a one-dose subunit vaccine for the induction of durable, potent, and broad immunity against SARS-CoV-2.

16 Dec 2022

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Researchers used serological measurements from a longitudinal cohort to evaluate the use of binding antibodies against the SARS-CoV-2 spike protein receptor binding domain as correlates of protection against the immune evasive Omicron subvariants BA.1 and BA.2.

16 Dec 2022

Common psychiatric medications can give some protection against COVID-19

A new meta-analysis shows that psychiatric medications can give some protection against COVID-19, with the common antidepressant fluvoxamine showing the strongest effect.

16 Dec 2022

Medical Research News

Novel immunotherapy offers a promising new strategy to fight hard-to-treat cancers

Study shows how a specific gut microbe-generated byproduct is linked to heart failure risk

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

NEJM study shows hidden genetic anomaly behind common late-onset cerebellar ataxia

Adult children four times more likely to be estranged from fathers than mothers

Structured analysis of personal criteria can make people more likely to save lives

Landmark population health study could pave the way for better tools to fight chronic diseases in Asian populations

People of all age groups benefit more from COVID-19 vaccines than natural immunity, real-world study finds

New support for a serotonin deficit in depression

ACS' new program associated with increased efficiency in treating pediatric trauma patients

High performing primary care practices for patients with diabetes during the pandemic

Walnut consumption has positive effects on stressed university students

Study provides new insights into the pathology of LATE

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

Adding Gli1+ cells could regenerate the enthesis after rotator cuff surgery

Outpatient clinic visits with a nephrologist associated with lower risk of mortality in patients with acute kidney injury

Study: People with cluster headaches may be more likely to have other medical conditions

Researchers report the development of robust candidate single immunization PNP hydrogel COVID vaccines

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Common psychiatric medications can give some protection against COVID-19

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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