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How does the interval between the 1st and 2nd BNT162b2 doses impact the neutralization breadth and potency against variants of concern?

Scientists explored the influence of SARS-CoV-2 extended gap vaccination on the variants of concern neutralization.

9 Aug 2022

Evaluating vaccine effectiveness against Omicron BA.5 and BA.2 in Portugal

Researchers estimated the vaccine effectiveness (VE) of the primary and booster doses of COVID-19 vaccines against reinfection by Omicron BA.5 and BA.2 lineages and severe post-infection outcomes.

9 Aug 2022

How did perceived social support across COVID-19 restrictions alter alcohol and cannabis use in emerging adults?

Researchers demonstrated changes in alcohol and cannabis use among young adults in Canada and the United States during pre-COVID-19 times, COVID-19-induced lockdown, and when social restrictions eased later.

9 Aug 2022

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Researchers evaluated the comparative pathogenicity of SARS-CoV-2 Omicron sub-variants BA.1, BA.2, and BA.5, in vitro and in vivo.

9 Aug 2022

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Scientists review current literature associated with the role of the gut-brain axis in AD pathogenesis.

9 Aug 2022

Experts use tools from artificial intelligence to rapidly identify substances that cause overdose deaths

An automated process based on computer algorithms that can read text from medical examiners' death certificates can substantially speed up data collection of overdose deaths – which in turn can ensure a more rapid public health response time than the system currently used, new UCLA research finds.

9 Aug 2022

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

A steroid hormone called aldosterone is linked to an increased risk of kidney failure in patients with chronic kidney disease (CKD), according to a study published in the European Heart Journal today (Tuesday).

8 Aug 2022

OU researchers receive nearly $1 million NSF grants for pandemic prediction and prevention projects

Two groups of researchers at the University of Oklahoma have each received nearly $1 million grants from the National Science Foundation as part of its Predictive Intelligence for Pandemic Prevention initiative, which focuses on fundamental research and capabilities needed to tackle grand challenges in infectious disease pandemics through prediction and prevention.

8 Aug 2022

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

In 2020, more than 1.5 million people around the world died of tuberculosis, marking the first time in more than a decade that annual TB deaths had increased and demonstrating the global need for better access to treatments.

8 Aug 2022

Exercise program improves physical functioning among older adults with chronic kidney disease

This randomized trial recently published in the American Journal of Kidney Diseases (AJKD) found that a 12- month program of in-center aerobic and resistance exercise program improved physical functioning among adults 55 years and older with CKD stages G3b-4 and a high level of medical comorbidities.

8 Aug 2022

Overnight EEG studies may help inform care for girls with Rett syndrome

In Rett syndrome, a genetic condition affecting girls almost exclusively, mutations in the MECP2 gene cause a regression of language and motor skills starting at 12 to 18 months of age.

8 Aug 2022

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Cystic fibrosis remains an incurable genetic disorder which impairs lung function and significantly reduces life expectancy.

8 Aug 2022

Disruption of the circadian clocks plays a key role in weight gain

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.

8 Aug 2022

Should pregnant women be included clinical trials?

The current study reports some of the scientific, ethical, and legal considerations that will support the inclusion of pregnant women in future research.

8 Aug 2022

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Young people who received doses of tisagenlecleucel, a chimeric antigen receptor T cell (CAR-T) therapy, at the higher end of the FDA-approved dosing range had significantly better survival rates at one year compared with those who received lower doses within this range, according to research published today in Blood Advances.

8 Aug 2022

Inflation problem in the U.S. impacts Black families more than many other Americans

A new NPR/Robert Wood Johnson Foundation/Harvard T.H. Chan School of Public Health poll shows that at a time when households across the U.S. widely report experiencing serious problems from inflation, Black Americans are substantially more likely than whites to report they are currently having serious financial problems in this period (55% to 38%).

8 Aug 2022

Medical Research News

How does the interval between the 1st and 2nd BNT162b2 doses impact the neutralization breadth and potency against variants of concern?

Evaluating vaccine effectiveness against Omicron BA.5 and BA.2 in Portugal

How did perceived social support across COVID-19 restrictions alter alcohol and cannabis use in emerging adults?

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Experts use tools from artificial intelligence to rapidly identify substances that cause overdose deaths

Aldosterone may increase risk of kidney failure in patients with chronic kidney disease

OU researchers receive nearly $1 million NSF grants for pandemic prediction and prevention projects

Researchers develop a long-acting injectable formulation of the anti-TB drug rifabutin

Exercise program improves physical functioning among older adults with chronic kidney disease

Overnight EEG studies may help inform care for girls with Rett syndrome

Combination therapy regimen for cystic fibrosis is also beneficial to primary school-aged children

Disruption of the circadian clocks plays a key role in weight gain

Should pregnant women be included clinical trials?

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Inflation problem in the U.S. impacts Black families more than many other Americans

Yale researchers discover molecular mechanism behind growth of the nervous system

Study explores the relationship between empathy and cyberbullying among early U.S. adolescents

COVID-19 vaccination increases antibodies in breast milk significantly

Sperm not affected nine months after COVID-19 mRNA vaccination

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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