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New initiative to improve HIV health outcomes for Black men who have sex with men

The results of a multi-year initiative aimed at improving HIV health outcomes for Black men who have sex with men (MSM) are published in a new Supplement in the peer-reviewed journal AIDS Patient Care and STDs.

27 Oct 2022

Study elucidates mechanism that is crucial for making hemophilia therapy effective

Hemophilia A is the most common severe form of hemophilia. It affects almost exclusively males. The disease can usually be treated well, but not for all sufferers.

27 Oct 2022

Research opens up new avenues for overcoming treatment resistance in colorectal cancer

Colorectal cancer is one of the most common cancers. Its treatment is mainly based on chemotherapy. However, over time, chemotherapy induces resistance in the majority of patients, who end up being unresponsive to the drugs.

27 Oct 2022

Study finds sexual dimorphism in the development of vascular insulin resistance induced by obesogenic lifestyle

A new study from the University of Missouri School of Medicine is the first evidence in humans that short-term lifestyle changes can disrupt the response to insulin of blood vessels. It's also the first study to show men and women react differently to these changes.

27 Oct 2022

Discovery points to a new understanding of Stargardt disease progression

Using a new stem-cell-based model made from skin cells, scientists found the first direct evidence that Stargardt-related ABCA4 gene mutations affect a layer of cells in the eye called the retinal pigment epithelium (RPE).

27 Oct 2022

Study examines the severity of the SARS-CoV-2 Omicron BA.2 subvariant

In a recent study that represents the largest to date to examine the severity of the SARS-CoV-2 Omicron BA.2 subvariant (the strain making a re-emergence this fall), a team led by investigators at Massachusetts General Hospital (MGH) determined that the BA.2 subvariant is less severe than the previous Delta variant and less severe to an even greater extent than the original Omicron variant.

27 Oct 2022

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

A fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.

27 Oct 2022

Studies find cardiovascular effects of cigarettes and e-cigarettes to be strikingly similar

Two related studies, one in humans and the other in rats, found that the cardiovascular effects of cigarettes and e-cigarettes are strikingly similar, and these harmful effects on blood vessel function are likely caused by airway irritation due to inhalation of a foreign substance, rather than a specific component of the cigarette smoke or e-cigarette vapor (aerosol), according to new research published today in the American Heart Association's peer-reviewed journal Arteriosclerosis, Thrombosis and Vascular Biology.

27 Oct 2022

Is vaccine status associated with the severity of Omicron SARS-CoV-2 infection in hospitalized patients?

Researchers assessed the impact of SARS-CoV-2 vaccination on the occurrence and severity of symptoms in SARS-CoV-2 Omicron-infected hospitalized patients.

27 Oct 2022

The effectiveness of BNT162b2 COVID-19 vaccine against infection with SARS-CoV-2 Omicron subvariants BA.4/5

Researchers evaluated the vaccine effectiveness of Pfizer-BioNTech’s BNT162b2 COVID-19 vaccines against SARS-CoV-2 Omicron BA.4/5.

27 Oct 2022

First report of natural recombination of monkeypox virus genome

Researchers analyzed monkeypox virus sequences during the current 2022 outbreak to investigate whether MPXV is adapting for improved survival and viral transmission among humans.

27 Oct 2022

Rare variants of type I IFN immunity genes could underlie life-threatening COVID-19

Researchers assessed whether loss-of-function variants of type I interferon immunity genes are associated with life-threatening COVID-19.

27 Oct 2022

What is the association between regular physical activity and vaccination against COVID-19 among healthcare workers?

Researchers assessed the association between daily physical activity and COVID-19 vaccination among HCWs.

27 Oct 2022

Vaccination- and/or natural infection-induced immune responses against SARS-CoV-2 Omicron subvariants

Researchers comparatively evaluated the neutralization antibody titers for SARS-CoV-2 Omicron VOC subvariants BA.1, BA.2, BA.4/5 among individuals with ancestral B.1 strain infections, vaccinated individuals, or with hybrid immunity from breakthrough infections and vaccinations with Delta or Gamma VOCs.

27 Oct 2022

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

Researchers reported three human monoclonal antibodies generated from COVID-19-recovered individuals during the initial wave of the pandemic in India.

27 Oct 2022

Study finds that ACE-2 is not biochemically required for SARS-CoV2 membrane fusion

A study tested the hypothesis that the ACE-2 receptor of SARS-CoV-2 is not only an attachment factor in viral infection but also plays a role in activating the viral spike protein to facilitate membrane fusion.

27 Oct 2022

Researchers develop new method to calculate the delay of signal propagations in brains of MS patients

Researchers of the Human Brain Project have developed a new methodology to calculate the delay of signal propagations in brains of patients suffering from multiple sclerosis, a chronic inflammatory disease that affects more than 2 million people worldwide.

27 Oct 2022

Metabolite product from pomegranate improves the function of immune cells to fight against cancer

As part of an interdisciplinary project of the LOEWE Centre Frankfurt Cancer Institute (FCI), researchers from the Georg-Speyer-Haus in Frankfurt am Main, Germany, and Goethe University Frankfurt have succeeded in identifying a new approach for the therapy of colorectal cancer.

27 Oct 2022

Some healthcare workers vaccinated against COVID-19 show unexpectedly low responses to immunizations

A subset of healthcare workers vaccinated against COVID-19 had unexpectedly low responses to the immunizations, according to Cedars-Sinai investigators.

27 Oct 2022

Cells in the brain's blood vessels necessary for fever reaction

Researchers at Linköping University have identified in mice the cells in the blood vessels of the brain that are necessary for a fever reaction.

26 Oct 2022

Medical Research News

New initiative to improve HIV health outcomes for Black men who have sex with men

Study elucidates mechanism that is crucial for making hemophilia therapy effective

Research opens up new avenues for overcoming treatment resistance in colorectal cancer

Study finds sexual dimorphism in the development of vascular insulin resistance induced by obesogenic lifestyle

Discovery points to a new understanding of Stargardt disease progression

Study examines the severity of the SARS-CoV-2 Omicron BA.2 subvariant

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

Studies find cardiovascular effects of cigarettes and e-cigarettes to be strikingly similar

Is vaccine status associated with the severity of Omicron SARS-CoV-2 infection in hospitalized patients?

The effectiveness of BNT162b2 COVID-19 vaccine against infection with SARS-CoV-2 Omicron subvariants BA.4/5

First report of natural recombination of monkeypox virus genome

Rare variants of type I IFN immunity genes could underlie life-threatening COVID-19

What is the association between regular physical activity and vaccination against COVID-19 among healthcare workers?

Vaccination- and/or natural infection-induced immune responses against SARS-CoV-2 Omicron subvariants

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

Study finds that ACE-2 is not biochemically required for SARS-CoV2 membrane fusion

Researchers develop new method to calculate the delay of signal propagations in brains of MS patients

Metabolite product from pomegranate improves the function of immune cells to fight against cancer

Some healthcare workers vaccinated against COVID-19 show unexpectedly low responses to immunizations

Cells in the brain's blood vessels necessary for fever reaction

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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