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OpenSAFELY study shows the effectiveness of Pfizer COVID booster doses

In a recent study posted to the medRxiv pre-print server, researchers assessed the effectiveness of the Pfizer–BioNTech BNT162b2 coronavirus disease 2019 (COVID-19) vaccine in the seven million United Kingdom (UK) adults who were eligible to receive booster shots between 16 September and 16 December 2021.

7 Jun 2022

Study finds added benefits of molnupiravir for non-hospitalized COVID-19 patients

In a recent investigation published in the Annals of Internal Medicine journal, scientists demonstrated the positive impacts of molnupiravir among severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients and the healthcare sector apart from lowering disease-linked deaths and hospitalizations in at-risk cohorts.

7 Jun 2022

Gastrointestinal complications caused by SARS-CoV-2

scientists discuss the gastrointestinal complications associated with COVID-19.

7 Jun 2022

How do viruses evolve to infect new hosts?

Researchers discuss how protein thermostability prevents the misfolding of viral proteins from being heated.

7 Jun 2022

Inequalities found in oral anticoagulant prescribing to reduce stroke risk in atrial fibrillation patients

There are racial and socioeconomic inequalities in the prescribing of oral anticoagulants to reduce stroke risk in people with atrial fibrillation, according to a new study conducted in the UK and publishing June 7th in the open-access journal PLOS Medicine by Alyaa Ajabnoor of the University of Manchester, United Kingdom, and colleagues.

7 Jun 2022

USC scientists receive more than $16 million to study the role of blood vessel dysfunction in Alzheimer’s disease

The National Institute on Aging, a division of the National Institutes of Health, awarded Berislav Zlokovic, MD, PhD, director of the Zilkha Neurogenetic Institute, and Arthur W. Toga, PhD, director of the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI), $16.1 million to continue research on the role that blood vessel dysfunction plays in the development of dementia and Alzheimer's disease.

7 Jun 2022

Scientists provide crucial insights into the roles of inflammation and oxidative stress in certain cancers

Rampant inflammation has long been linked to cancer but exactly how it pushes healthy cells to transform into malignant ones has remained a mystery.

7 Jun 2022

Ketogenic diets may help ward off polycystic kidney disease

The team of UC Santa Barbara biochemist Thomas Weimbs published the results of a clinical study that gives the first indication that ketogenic diets may be safe and effective in patients with polycystic kidney disease (PKD).

7 Jun 2022

Manufacturers and suppliers influence how pharmacies buy, distribute opioid prescriptions, study finds

In today's post-pandemic world, strained global supply chains have emerged as a new norm. But in the case of prescription opioids, namely oxycodone and hydrocodone in the early 2000s, that supply chain flowed freely without any kinks.

7 Jun 2022

People with HIV are at greater risk of breakthrough COVID-19 infections after vaccination

People with HIV have a higher rate of breakthrough COVID-19 infections after vaccination, compared to people without HIV, according to findings from a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

7 Jun 2022

Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have found that oral administration of rapamycin to an Alzheimer's disease mouse model causes an increase in beta (β)-amyloid protein plaques. β-amyloid buildup is a hallmark of Alzheimer's disease.

7 Jun 2022

Obesity increases the risk of undergoing knee replacement at a younger age

More than half of Australians who underwent knee replacement for osteoarthritis were obese, increasing their risk of having the operation at a younger age, especially among women.

7 Jun 2022

Com-COV 3 study focuses on assessing a third dose booster vaccination for young people aged 12 to 15

The Com-COV 3 study has been commissioned through the NIHR and backed by £2.8 million government funding, with support from both the Vaccine Taskforce and National Institute for Health and Care Research (NIHR).

7 Jun 2022

COVID-19 vaccination may offer less effective and shorter-lasting protection for some cancer patients

A study co-led by the Universities of Oxford, Birmingham and Southampton and the UK Health Security Agency (UKHSA), published in Lancet Oncology today by the UK Coronavirus Cancer Evaluation Project, has found that while COVID-19 vaccination is effective in most cancer patients, the level of protection against COVID-19 infection, hospitalization and death offered by the vaccine is less than in the general population and vaccine effectiveness wanes more quickly.

7 Jun 2022

Major study reveals key differences in brain structure between people with and without anorexia

A major study, coordinated by neuroscientists at the University of Bath (UK) with international partners, has revealed key differences in brain structure between people with and without anorexia nervosa.

7 Jun 2022

Study identifies some breast cancer patients who can avoid radiotherapy

Older women with early-stage breast cancer may not need radiotherapy after undergoing surgery, McMaster University researcher Timothy Whelan and his team has found.

7 Jun 2022

Study: Weight-loss surgery reduces cancer incidence and deaths

Individuals with obesity were at least two times more likely to develop certain types of cancer and 3.5 times more likely to die from from the disease than those who had weight-loss surgery, according to a new study presented here today at the American Society for Metabolic and Bariatric Surgery Annual Meeting.

7 Jun 2022

The effect of Omicron breakthrough infection on the magnitude and breadth of serum neutralizing activity and memory B cells among BNT162b2 vaccinees

Researchers evaluated the impact of breakthrough infections with SARS-CoV-2 Omicron BA.1 sublineage on SARS-CoV-2 variants of concern neutralization and memory B lymphocytes formation among BNT162b2 vaccinees.

7 Jun 2022

Molecular modeling techniques describe the process of interaction between nanotubes and the main structures of SARS-CoV-2

Researchers assessed the interactions between carbon nanotubes and SARS-CoV-2.

7 Jun 2022

De novo-designed mini-protein against SARS-CoV-2

Researchers characterized truncated forms of LCB1, a de novo-designed mini-protein, against SARS-CoV-2.

7 Jun 2022

Medical Research News

OpenSAFELY study shows the effectiveness of Pfizer COVID booster doses

Study finds added benefits of molnupiravir for non-hospitalized COVID-19 patients

Gastrointestinal complications caused by SARS-CoV-2

How do viruses evolve to infect new hosts?

Inequalities found in oral anticoagulant prescribing to reduce stroke risk in atrial fibrillation patients

USC scientists receive more than $16 million to study the role of blood vessel dysfunction in Alzheimer’s disease

Scientists provide crucial insights into the roles of inflammation and oxidative stress in certain cancers

Ketogenic diets may help ward off polycystic kidney disease

Manufacturers and suppliers influence how pharmacies buy, distribute opioid prescriptions, study finds

People with HIV are at greater risk of breakthrough COVID-19 infections after vaccination

Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Obesity increases the risk of undergoing knee replacement at a younger age

Com-COV 3 study focuses on assessing a third dose booster vaccination for young people aged 12 to 15

COVID-19 vaccination may offer less effective and shorter-lasting protection for some cancer patients

Major study reveals key differences in brain structure between people with and without anorexia

Study identifies some breast cancer patients who can avoid radiotherapy

Study: Weight-loss surgery reduces cancer incidence and deaths

The effect of Omicron breakthrough infection on the magnitude and breadth of serum neutralizing activity and memory B cells among BNT162b2 vaccinees

Molecular modeling techniques describe the process of interaction between nanotubes and the main structures of SARS-CoV-2

De novo-designed mini-protein against SARS-CoV-2

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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