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NIH awards 103 new grants to support meritorious behavioral and biomedical research projects

The High-Risk, High-Reward Research program, supported by the Common Fund at the National Institutes of Health has awarded 103 new research grants to support highly innovative scientists who propose visionary and broadly impactful meritorious behavioral and biomedical research projects.

4 Oct 2022

Comparative immunogenicity of COVID-19 vaccines in North California

In new research, researchers evaluated vaccine responses among North Californian residents, including differences in vaccine side effects and antibody (Ab) titers by age, sex, and vaccine type.

4 Oct 2022

What is the COVID-19 mRNA-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variants?

Researchers evaluated the messenger ribonucleic acid (mRNA)-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variant of concern infections and hospitalizations.

4 Oct 2022

Model simulations for use of rapid antigen testing for COVID-19 diagnosis

In new research, researchers overviewed the impact of rapid antigen tests use cases with and without surveillance; hospital-based screening to decrease nosocomial COVID-19, and COVID-19 testing to enable prompt and expanded treatment for different country settings.

4 Oct 2022

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

In a new study, researchers evaluated the anti-cancer therapeutic efficacy of two structurally-unrelated small molecules, PAV-617 and PAV-951.

4 Oct 2022

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

In a new study, researchers identified distinguishing immune features of coronavirus disease 2019 (COVID-19) in patients with late-resolving pulmonary fibrosis (LR COVID-PF) and early-resolving (ER COVID-PF).

4 Oct 2022

Study attributes increased transmissibility of Monkeypox Clade IIb to genomic accordions

In a new study, researchers performed a genomic study of confirmed Monkeypox virus (MPXV) cases diagnosed in Spain between 18 May and 14 July 2022.

4 Oct 2022

What are the challenges of COVID-19 vaccination and herd immunity?

A new study reviewed the challenges of coronavirus disease 2019 (COVID-19) vaccination and herd immunity.

4 Oct 2022

What are the genetic associations of stroke pathogenesis across ancestry groups?

In new research, researchers identified genetic associations of stroke pathogenesis.

4 Oct 2022

Can you shed infectious SARS-CoV-2 virions even if COVID vaccinated?

Researchers in the United States published a study in the journal PLOS Pathogens that examined the shedding of infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virions despite vaccination against it.

4 Oct 2022

Are infants younger than six months at higher risk of SARS-CoV-2 infections?

In a recent study posted to the medRxiv* preprint server, a team of researchers in the United States examined the incidence and associated characteristics of medically attended coronavirus disease 2019 (COVID-19) episodes in infants below six months of age.

4 Oct 2022

Nursing home study shows 4th COVID mRNA dose provides extra protection against severe Omicron outcomes

In a recent study posted to the medRxiv* preprint server, researchers in Canada assessed the effectiveness of protection elicited by the fourth dose of the coronavirus disease 2019 (COVID-19) mRNA vaccine.

4 Oct 2022

Spike-specific memory B cells develop resilience to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers explored the cross-reactivity, avidity, and kinetics of memory B-cells and serum antibodies in vaccinated and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals.

4 Oct 2022

New analysis highlights the need to prioritize addressing preventable vision loss in children in America

An analysis of the nation's first and largest comprehensive eye disease registry, the IRIS® Registry, sheds new light on what we thought we knew about childhood blindness in the United States: The leading causes appear to be retinopathy of prematurity (ROP), nystagmus, and cataract, mostly treatable and preventable causes.

3 Oct 2022

Wearing masks for health reasons influences people to behave more ethically, research says

Since 2020, the Covid-19 pandemic has led to a global increase in the number of people wearing masks to limit the spread of illness.

3 Oct 2022

Research maps how infectious diseases spread at human-wildlife ‘hotspots’

New research has mapped how infectious diseases spread among wildlife populations in areas where humans and wildlife live in close proximity.

3 Oct 2022

How COVID-19 affects the female reproductive system

A new review in the Biology of Reproduction journal analyzed the relationship between the immune system and the female reproductive system while focusing on the effects of COVID-19-associated immune responses on the reproductive system. The study searched PubMed to identify peer-reviewed literature in English up to May 2022 and finally included 83 studies.

3 Oct 2022

Sudden cardiac death risk can be determined by genetic score

A recent study published in the Journal of the American College of Cardiology found that a genome-wide polygenic score for coronary artery disease (GPSCAD) can predict sudden and/or arrhythmic death (SAD) risk in coronary artery disease (CAD) patients without severe systolic dysfunction.

3 Oct 2022

Study: Lack of naloxone linked to high rates of overdose deaths in rural areas

Pennsylvania has one of the highest rates of opioid overdose in the nation, and, according to Penn State researchers, one's chances of surviving that overdose can depend on where the person lives.

3 Oct 2022

Study reveals a promising therapeutic target for spinocerebellar ataxia type 14

Spinocerebellar ataxias are a group of neurodegenerative diseases characterized by the degeneration of Purkinje cells, a major class of neurons in the cerebellum.

3 Oct 2022

Medical Research News

NIH awards 103 new grants to support meritorious behavioral and biomedical research projects

Comparative immunogenicity of COVID-19 vaccines in North California

What is the COVID-19 mRNA-1273 vaccine effectiveness against SARS-CoV-2 Omicron sub-variants?

Model simulations for use of rapid antigen testing for COVID-19 diagnosis

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

Study attributes increased transmissibility of Monkeypox Clade IIb to genomic accordions

What are the challenges of COVID-19 vaccination and herd immunity?

What are the genetic associations of stroke pathogenesis across ancestry groups?

Can you shed infectious SARS-CoV-2 virions even if COVID vaccinated?

Are infants younger than six months at higher risk of SARS-CoV-2 infections?

Nursing home study shows 4th COVID mRNA dose provides extra protection against severe Omicron outcomes

Spike-specific memory B cells develop resilience to SARS-CoV-2

New analysis highlights the need to prioritize addressing preventable vision loss in children in America

Wearing masks for health reasons influences people to behave more ethically, research says

Research maps how infectious diseases spread at human-wildlife ‘hotspots’

How COVID-19 affects the female reproductive system

Sudden cardiac death risk can be determined by genetic score

Study: Lack of naloxone linked to high rates of overdose deaths in rural areas

Study reveals a promising therapeutic target for spinocerebellar ataxia type 14

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

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