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Vaccinated people with breakthrough SARS-CoV-2 infection can experience debilitating long COVID

Even vaccinated people with mild breakthrough COVID-19 infections can experience debilitating, lingering symptoms that affect the heart, brain, lungs and other parts of the body, according to new research from Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System.

25 May 2022

Epigenetic markers associated with different risks of developing complications in type 2 diabetes

A new study by researchers at Lund University supports the notion that patients with type 2 diabetes patient should be divided into subgroups and given individualized treatment.

25 May 2022

Air pollutant exposures can exacerbate the effects of the SARS-CoV-2 infection

Data from a new USC study shows a significant increase in the risk of severe outcomes for COVID-19 patients exposed to fine particles (PM2.5) and nitrogen dioxide (NO2), two common (and correlated) components of ambient air pollution in Southern California.

25 May 2022

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Researchers investigated the impact of coronavirus disease 2019 (COVID-19) on biomarkers in the cerebrospinal fluid (CSF).

25 May 2022

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reviewed available mucosal vaccines discussing the current challenges and ways to advance the existing approaches.

25 May 2022

NTU scientists discover why NAFLD patients are at higher risk of cardiovascular disease

Patients with non-alcoholic fatty liver disease (NAFLD) are at higher risk of cardiovascular disease, because NAFLD prompts the over-production of a class of proteins that cause inflammation and damage to their blood vessels.

25 May 2022

HKUMed researchers report the effects of SARS-CoV-2 on bone metabolism

A research team led by Professor Kelvin Yeung Wai-kwok and Dr Jasper Chan Fuk-woo from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that SARS-CoV-2 infection can cause inflammatory activation of bone resorption cells, leading to severe bone loss during the acute and post-recovery phases of COVID-19.

25 May 2022

Researchers propose DLPE method to extract interpretable and predictive subvisual features from CT scans of COVID-19 inpatients and survivors

Researchers assessed deep learning workflows involved in CT scans of COVID-19.

25 May 2022

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

Researchers compared the efficacy of sotrovimab and molnupiravir in preventing severe COVID-19 outcomes among non-hospitalized and high-risk COVID-19 patients across England.

25 May 2022

The effectiveness of molnupiravir and nirmatrelvir/ritonavir in reducing hospitalization and deaths in non-hospitalized COVID-19 patients

Researchers assessed the effectiveness of two orally administered antiviral medications, nirmatrelvir/ritonavir, and molnupiravir, in decreasing hospitalization and deaths among real-world non-hospitalized COVID-19 patients in Hong Kong.

25 May 2022

Study investigates associations between antibody response to COVID-19 vaccination and the risk of subsequent infection

Researchers investigated the associations between antibody levels against SARS-CoV-2 and the risk of subsequent infection.

25 May 2022

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

In a recent study posted to the Research Square* preprint server, researchers assessed whether disturbances in the gut microbiota weaken the serological response to the coronavirus disease 2019 (COVID-19) vaccine in inflammatory bowel disease (IBD) patients.

25 May 2022

A study on the safety of BNT162b2 COVID vaccine in children under five

In a recent research paper posted to the medRxiv* preprint server, scientists explored the safety of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BNT162b2 vaccine in children under five years of age.

25 May 2022

Association between reactogenicity and immunogenicity in SARS-CoV-2 mRNA-1273 vaccination

A recent study currently under review at Scientific Reports journal and posted to the Research Square* preprint server demonstrated a potential positive correlation between reactogenicity and immunogenicity of coronavirus disease 2019 (COVID-19) vaccination.

25 May 2022

The root causes of long-COVID still a mystery

In a recent article posted to the journal Annals of Internal Medicine, researchers presented baseline outcomes from a longitudinal assessment of post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC), also known as long-COVID.

25 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Researchers propose new imaging method to study neural networks in living brains

The brain is made up of a complex series of networks-signals are constantly bouncing between those networks to allow us to experience the world and move through it effectively.

25 May 2022

Correlation between long-COVID and physical inactivity

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers assessed whether physical inactivity in coronavirus disease 2019 (COVID-19) survivors led to the development of post-acute sequelae of COVID-19 (PASC), also known as long-COVID.

25 May 2022

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies chemotherapy. However, the siRNAs need a delivery vehicle to protect them from degradation and clearance on their journey through the bloodstream to the cancer tumor.

25 May 2022

Largest study to date on long COVID identifies a broad list of diagnoses

Researchers characterize post-acute sequelae of SARS-CoV-2 infection.

25 May 2022

Medical Research News

Vaccinated people with breakthrough SARS-CoV-2 infection can experience debilitating long COVID

Epigenetic markers associated with different risks of developing complications in type 2 diabetes

Air pollutant exposures can exacerbate the effects of the SARS-CoV-2 infection

Study measures viral antigen and inflammatory biomarkers in CSF of COVID-19 patients in relation to neurologic symptoms and disease severity

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

NTU scientists discover why NAFLD patients are at higher risk of cardiovascular disease

HKUMed researchers report the effects of SARS-CoV-2 on bone metabolism

Researchers propose DLPE method to extract interpretable and predictive subvisual features from CT scans of COVID-19 inpatients and survivors

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

The effectiveness of molnupiravir and nirmatrelvir/ritonavir in reducing hospitalization and deaths in non-hospitalized COVID-19 patients

Study investigates associations between antibody response to COVID-19 vaccination and the risk of subsequent infection

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

A study on the safety of BNT162b2 COVID vaccine in children under five

Association between reactogenicity and immunogenicity in SARS-CoV-2 mRNA-1273 vaccination

The root causes of long-COVID still a mystery

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Researchers propose new imaging method to study neural networks in living brains

Correlation between long-COVID and physical inactivity

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Largest study to date on long COVID identifies a broad list of diagnoses

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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