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Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Researchers characterized the responses of the PBMCs at the individual cell and cell type levels against SARS-CoV-2 and SARS-CoV ex vivo.

18 Feb 2022

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Researchers evaluated the efficacy of an mRNA vaccine booster dose against severe acute respiratory syndrome coronavirus-2 during the Omicron surge.

18 Feb 2022

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Researchers investigated the connecting link between viral genetic variability and clinical heterogeneity of COVID-19 by analyzing the effect of several missense mutations on the ACE2 receptor coding sequence.

18 Feb 2022

Changes in the brain cortex of COVID-19 patients associated with inflammatory biomarkers

Recently, a team of researchers examined the neurotoxic damage to the brain’s cortical region in patients hospitalized due to COVID-19.

18 Feb 2022

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

A recent study explored the safety, immunogenicity, and VE of the SARS-CoV-2 mRNA BNT162b2 and mRNA1273 vaccines against its Omicron VOC in HCWs in Israel.

18 Feb 2022

mRNA vaccine-induced antibodies shown to be more effective in neutralizing SARS-CoV-2 and its variants than natural immunity

Researchers designed an electrochemiluminescence-based serology test with remarkable sensitivity to precisely quantify the amounts of anti-RBD antibodies in individuals infected with SARS-CoV-2.

18 Feb 2022

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Researchers have been examining the pathology and spread of the Omicron variant in mink.

18 Feb 2022

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Researchers developed a ‘bait and capture’ system which was further followed by a multiplexed and targeted proteomic liquid chromatography-tandem mass spectrometry analyses for the comparison of immune correlates in response to vaccination, natural infection, as well as protection against SARS-CoV-2 variants.

18 Feb 2022

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

A new study aimed to clarify whether extensive RBD mutations could affect the magnitude and immunodominance hierarchy of the host antibody response.

18 Feb 2022

Novel blood biomarkers can potentially predict melanoma patients' response to immunotherapy

Melanoma, a type of skin cancer, is often curable when detected and treated in its early stages. However, the disease can rapidly spread to other organs in the body and become deadly. According to the American Cancer Society, more than 7,600 people die of the disease each year in the United States.

17 Feb 2022

Exposure to endocrine disrupting mixtures during pregnancy impacts children's brain development

By linking human population studies with experiments in cell and animal models, researchers have provided evidence that complex mixtures of endocrine disrupting chemicals impact children's brain development and language acquisition.

17 Feb 2022

Only half of the people with cardiovascular disease risk receive lifestyle support from GPs, study shows

A new 10-year analysis of people in England newly diagnosed with high blood pressure, high cholesterol or obesity shows only half receive lifestyle support from their GPs.

17 Feb 2022

Advanced imaging reveals the loss of brain synapses in patients with mild symptoms of Alzheimer's

Advanced imaging technology developed by Yale researchers has helped them confirm that the destruction of brain synapses underlies the cognitive deficits experienced by patients with Alzheimer's disease, according to a study published Feb. 17 in the journal Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

17 Feb 2022

COVID test-to-return may help shorten time away from school

In a recent study posted to the medRxiv* preprint server, a test-to-return approach for students in isolation is explored for its utility in sorting out students who can safely return to school without jeopardizing others, from those with a high viral load.

17 Feb 2022

Covid-19 linked with an increased risk of mental health disorders, study finds

A study published by The BMJ today finds that covid-19 is associated with an increased risk of mental health disorders, including anxiety, depression, substance use, and sleep disorders, up to one year after initial infection.

17 Feb 2022

Study finds 'substantial decrease' in people's mental wellbeing since the start of the pandemic

People in the UK have experienced a "substantial decrease" in mental wellbeing since the start of the Covid pandemic - according to new research from the University of East Anglia and University of York.

17 Feb 2022

New insights could help long-term care facilities enhance infection prevention and control measures

Findings from a study published today in the American Journal of Infection Control provide new insights that could help long-term care facilities assess the cleanliness of high-touch surfaces, and thereby enhance infection prevention and control measures designed to prevent serious diarrheal diseases and deaths among their residents.

17 Feb 2022

Medical Research News

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Changes in the brain cortex of COVID-19 patients associated with inflammatory biomarkers

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

mRNA vaccine-induced antibodies shown to be more effective in neutralizing SARS-CoV-2 and its variants than natural immunity

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

Novel blood biomarkers can potentially predict melanoma patients' response to immunotherapy

Exposure to endocrine disrupting mixtures during pregnancy impacts children's brain development

Only half of the people with cardiovascular disease risk receive lifestyle support from GPs, study shows

Advanced imaging reveals the loss of brain synapses in patients with mild symptoms of Alzheimer's

COVID test-to-return may help shorten time away from school

Covid-19 linked with an increased risk of mental health disorders, study finds

Study finds 'substantial decrease' in people's mental wellbeing since the start of the pandemic

New insights could help long-term care facilities enhance infection prevention and control measures

How accurate are rapid antigen COVID tests?

Trial of early antiviral therapy for COVID-19 shows no significant benefit

Ensitrelvir, a novel SARS-CoV-2 antiviral

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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