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Risk of SARS-CoV-2 reinfection in children compared to adults

The current study aimed to explore the rate and risk of SARS-CoV-2 reinfections in children.

14 Dec 2021

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

A group of researchers from various institutions developed a nucleoside-modified mRNA vaccine that encodes the SARS-CoV-2 N protein (mRNA-N) and is formulated in lipid nanoparticles for this investigation (LNP).

14 Dec 2021

Machine learning method for determining impact of mutations in the SARS-CoV-2 RBD on binding and antibody escape

Deep mutational learning (DML) is a technique developed by researchers from multiple institutions that combines experimental yeast display screening of RBD mutagenesis libraries with deep sequencing and machine learning.

14 Dec 2021

Mental health burden experienced in Sweden during COVID-19 pandemic

A new study aimed to determine the mental health burden of adults in Sweden through the data collected in the Omtanke2020 Study between 9th June 2020 and 8th June 2021.

14 Dec 2021

Study may offer insights into novel therapeutic strategies to treat COVID-19 related blood clots

Blood clots or thromboembolic complications in patients with COVID-19 are associated with increased levels of various proteins that cause blood to clot, compared with people with blood clots unrelated to COVID-19, according to a small study by Yale Cancer Center researchers.

14 Dec 2021

Characteristics of SARS-CoV-2 breakthrough infections tracked in large US study

Researchers from Microsoft Corporation, Fred Hutch Cancer Research Center, and the University of Washington recently published a report on the preprint server medRxiv* wherein they studied a de-identified cohort from the United States medical claims records from Change Healthcare to estimate the risk of hospitalization and death, by vaccine type and by previous SARS-CoV2 infection, among SARS-CoV-2 breakthrough infections in fully vaccinated individuals.

14 Dec 2021

SARS-CoV-2 transmission through indoor aerosols

A recent review published in the International Journal of Indoor Environment and Health presents the science behind the person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an indoor environment.

14 Dec 2021

Trial in sub-Saharan Africa evaluates the efficacy of COVID-19 vaccine in people living with HIV

A highly anticipated clinical trial in eight sub-Saharan countries is the first to specifically evaluate the efficacy of a COVID-19 vaccine in people living with HIV, including those with poorly controlled infections.

13 Dec 2021

Phenome study reveals alternate associations with SARS-CoV-2 risk loci

Researchers from the Duke Molecular Physiology Institute have been investigating genetic associations with more severe disease and examining the associations that certain genetic features have with other diseases.

13 Dec 2021

Case report highlights limitations of remote monitoring for early detection of CRM device battery failure

Even after the Food and Drug Administration issued a safety notice and recall, manufacturing defects in certain cardiac rhythm management (CRM) devices led to premature battery depletion that was not picked up by remote monitoring.

13 Dec 2021

Omicron variant may strike double vaccinated

Largely, scientists are skeptical that the Omicron variant can infect vaccinated individuals. However, a new study published on the medRxiv* preprint server has conducted neutralization assays using an Omicron isolate obtained from patients residing in the United Kingdom.

13 Dec 2021

Lymphoma patients can benefit from early CAR T treatment, study shows

Chimeric antigen receptor T-cell therapy or CAR T is a breakthrough treatment for patients with certain types of blood cancers.

13 Dec 2021

COVID-19 vaccines offer protection for multiple myeloma patients, but lesser than other cancer survivors

For patients with the blood cancer multiple myeloma, vaccination against COVID-19 provides some protection against coronavirus infection but to a far lower degree than the general population of cancer survivors, a new study by Dana-Farber Cancer Institute investigators shows.

13 Dec 2021

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

A new study published on the bioRxiv preprint server has hypothesized that T cell receptors (TCR) repertoire can measure the response to vaccines, as it would identify the TCR of clones that respond to the vaccination.

13 Dec 2021

Large study reveals increased rates of myeloma precursor condition in high-risk groups

The first results from the largest screening study yet conducted in the United States of individuals at above-average risk for the blood cancer multiple myeloma have revealed higher rates of a myeloma precursor condition in older adults who are Black or who have a close family member with a current or past blood cancer.

13 Dec 2021

Hotel-based protective housing minimizes COVID-19 rates in vulnerable homeless population

Persons experiencing homelessness (PEH) who were at high risk of severe COVID-19 were 2.5 times less likely to contract SARS-CoV-2 if they were provided with individual hotel rooms and medical and social support compared to citywide rates in homeless shelters, according to new research from the University of Chicago Medicine, Lawndale Christian Health Center, and the Chicago Department of Public Health.

13 Dec 2021

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

A recent review in the journal Life provided a detailed description of CRISPR-Cas-based diagnostic techniques to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but also emphasized the potential use of this technology towards developing effective molecular diagnostic platforms for any future pandemic.

13 Dec 2021

A model-based evaluation on the effectiveness of social distancing in COVID

Researchers utilize a mathematical model-based analysis to assess how social distancing measures contained the COVID-19 pandemic and reduced mortality.

13 Dec 2021

Combination treatment can provide long remissions for young patients with chronic lymphocytic leukemia

Young patients with chronic lymphocytic leukemia (CLL) can enjoy long remissions on the drug ibrutinib, but must stay on it indefinitely to keep the cancer in remission.

13 Dec 2021

Music interventions can provide 'psychological first aid' to stressed patients during lockdown

A violinist playing a soothing melody tailored to a patient's particular medical condition and personal musical preferences in the hospital can provide "psychological first aid," reports a new Northwestern Medicine study about neurological patients who received tele-music therapy during the COVID-19 pandemic lockdown.

13 Dec 2021

Medical Research News

Risk of SARS-CoV-2 reinfection in children compared to adults

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

Machine learning method for determining impact of mutations in the SARS-CoV-2 RBD on binding and antibody escape

Mental health burden experienced in Sweden during COVID-19 pandemic

Study may offer insights into novel therapeutic strategies to treat COVID-19 related blood clots

Characteristics of SARS-CoV-2 breakthrough infections tracked in large US study

SARS-CoV-2 transmission through indoor aerosols

Trial in sub-Saharan Africa evaluates the efficacy of COVID-19 vaccine in people living with HIV

Phenome study reveals alternate associations with SARS-CoV-2 risk loci

Case report highlights limitations of remote monitoring for early detection of CRM device battery failure

Omicron variant may strike double vaccinated

Lymphoma patients can benefit from early CAR T treatment, study shows

COVID-19 vaccines offer protection for multiple myeloma patients, but lesser than other cancer survivors

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

Large study reveals increased rates of myeloma precursor condition in high-risk groups

Hotel-based protective housing minimizes COVID-19 rates in vulnerable homeless population

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

A model-based evaluation on the effectiveness of social distancing in COVID

Combination treatment can provide long remissions for young patients with chronic lymphocytic leukemia

Music interventions can provide 'psychological first aid' to stressed patients during lockdown

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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