Study confirms accuracy of new generation GastroPanel® test

A clinical validation study conducted at Oulu University Hospital (OUH) has confirmed the high accuracy of BIOHIT Oyj’s new generation GastroPanel® test for the diagnosis of atrophic gastritis (AG) and Helicobacter pylori (Hp) infection in patients referred for gastroscopy.1 This unique blood test is designed for the first-line diagnosis of Hp infection and AG in patients with upper abdominal symptoms, such as dyspepsia and gastro-oesophageal reflux disease (GORD), before endoscopy. GastroPanel is also the only test on the market capable of monitoring the regulatory mechanism of acid output in the stomach.

GastroPanel diagnostic tests

GastroPanel diagnostic tests. Image Credit: BIOHIT HealthCare Ltd

Hp infection, AG and high acid output are important risk factors for gastric and oesophageal cancers. The new generation (unified) GastroPanel test works on the same principle as the original GastroPanel ELISA test and is designed to harmonize the ELISA processing conditions of four biomarkers. This highly informative assay is therefore a cost-effective solution for population-based screening for the risk of gastric cancer in asymptomatic and symptomatic individuals, and its efficacy has already been confirmed by several studies in both high- and low-risk countries.

This latest study evaluated the diagnostic accuracy of the new generation GastroPanel test for the diagnosis of both AG and Hp infection in patients referred for gastroscopy from Primary Care with different indications. Along with the previously published clinical validation studies,2,3 this biopsy-confirmed study was designed to verify the diagnostic capabilities of the new generation GastroPanel test compared to the current gold standard (gastroscopy and biopsy analysis), and to demonstrate its performance was comparable to the original GastroPanel test. The positive results from this study also pave the way for BIOHIT’s new GastroPanel Quick Test (point of care test) which will be launched in Q1 2022.

A total of 522 patients referred for gastroscopy at the Gastro Centre, OUH, were consented and enrolled for this particular study. Blood was sampled for all patients using the GastroPanel test, along with performing quality-controlled gastroscopies with mucosal biopsies. The results confirmed that the new generation GastroPanel is a highly accurate test for the non-invasive diagnosis of AG and Hp infection in patients referred for diagnostic gastroscopies.”

Dr. Olli-Pekka Koivurova, Principal Investigator, OUH

For more information visit: www.biohithealthcare.co.uk/gastropanel.

  1. Koivurova O-P, et al. Serological biomarker panel in diagnosis of atrophic gastritis and Helicobacter pylori infection in gastroscopy referral patients. Clinical validation of the new generation GastroPanel® test. Anticancer Res. 2021, 41, 5527-5537.
  2. Koivurova O-P, et al. Screening of the patients with autoimmune thyroid disease (AITD) and type 1 diabetes mellitus (DM1) for atrophic gastritis (AG) by serological biomarker testing (GastroPanel®). EC Gastroenterol. Digest. Syst, 2020, 7, 181-195.
  3. Mäki M, et al. Helicobacter pylori (Hp) IgG ELISA of the new-generation GastroPanel® is highly accurate in diagnosis of Hp-Infection in gastroscopy referral patients. Anticancer Res, 2020, 40, 6387-6398.

Citations

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    BIOHIT HealthCare Ltd. (2022, May 09). Study confirms accuracy of new generation GastroPanel® test. News-Medical. Retrieved on October 13, 2024 from https://www.news-medical.net/news/20220506/Study-confirms-accuracy-of-new-generation-GastroPanelc2ae-test.aspx.

  • MLA

    BIOHIT HealthCare Ltd. "Study confirms accuracy of new generation GastroPanel® test". News-Medical. 13 October 2024. <https://www.news-medical.net/news/20220506/Study-confirms-accuracy-of-new-generation-GastroPanelc2ae-test.aspx>.

  • Chicago

    BIOHIT HealthCare Ltd. "Study confirms accuracy of new generation GastroPanel® test". News-Medical. https://www.news-medical.net/news/20220506/Study-confirms-accuracy-of-new-generation-GastroPanelc2ae-test.aspx. (accessed October 13, 2024).

  • Harvard

    BIOHIT HealthCare Ltd. 2022. Study confirms accuracy of new generation GastroPanel® test. News-Medical, viewed 13 October 2024, https://www.news-medical.net/news/20220506/Study-confirms-accuracy-of-new-generation-GastroPanelc2ae-test.aspx.

Comments

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment
Post

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.