Biochemistry

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Pancreatic β cell-derived exosomal miR-29s manipulate glucose homeostasis

In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29s) via exosomes in response to high levels of free fatty acids (FFAs).

22 Jan 2021

Marine microalgae could be the solution to world's meat protein shortage

Marine microalgae-based cellular agriculture is a promising new way to sustainably produce plant-based 'meat' and healthy 'superfoods' for the future.

22 Jan 2021

Specific NSAIDs are metabolized by acyl-CoA synthetases leading to liver toxicity

Liver injury is a rare side effect of nonsteroidal anti-inflammatory drugs (NSAIDs), which are frequently used for daily pain control.

22 Jan 2021

Sloan Kettering Institute researchers offer a new answer to 100-year-old cancer mystery

The year 2021 marks the 100th anniversary of a fundamental discovery that's taught in every biochemistry textbook. In 1921, German physician Otto Warburg observed that cancer cells harvest energy from glucose sugar in a strangely inefficient manner: rather than "burn" it using oxygen, cancer cells do what yeast do -- they ferment it.

22 Jan 2021

Scientists discover mechanism for transient memory lapse

In a landmark neurobiology study, scientists from Scripps Research have discovered a memory gating system that employs the neurotransmitter dopamine to direct transient forgetting, a temporary lapse of memory which spontaneously returns.

21 Jan 2021

Researchers discover potent antifungal agent from attine ant farms

Attine ants are farmers, and they grow fungus as food. Pseudonocardia and Streptomyces bacteria are their farmhands, producing metabolites that protect the crop from pathogens.

20 Jan 2021

New method reveals how pharmaceuticals induce cancer cell death

Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time.

19 Jan 2021

Magnetic nanoparticles guide neurite growth in dopaminergic cells

Magnetic nanoparticles raise hopes of treatments for Parkinson’s.

19 Jan 2021

Researchers develop a technique to modify biological polymers with protein-based biochemical messages

Imagine going to a surgeon to have a diseased or injured organ switched out for a fully functional, laboratory-grown replacement. This remains science fiction and not reality because researchers today struggle to organize cells into the complex 3D arrangements that our bodies can master on their own.

18 Jan 2021

Study improves understanding of the chemistry behind potent antibiotic synthesis

Images of a protein involved in creating a potent antibiotic reveal the unusual first steps of the antibiotic's synthesis.

18 Jan 2021

CoQ10 supplement could be a valuable complementary therapeutic option for various diseases

A study led by scientists from the University of Granada (UGR) has found that a supplement of Coenzyme Q10 (CoQ10), an essential molecule for life that is synthesized in the cells of our organs and tissues and is also acquired through diet, could constitute a valuable complementary therapeutic option in the treatment of certain mitochondrial diseases, colon cancer, thyroid carcinoma, and Crohn’s disease.

18 Jan 2021

Australian scientists develop a new method for rapid synthesis of safe vaccines

With COVID-19 dominating medical science and human concern, our chemists have developed a method to quickly and safely synthesize protein vaccines for respiratory diseases for pre-clinical tests.

18 Jan 2021

Study reveals new way to target cancer’s nutritional needs

Scientists discover a way to target cancer’s nutritional needs, which could lead to a new way to treat the disease, according to a study published in Nature Communications today (Thursday).

18 Jan 2021

Researchers design new biosynthetic pathways for short-chain primary amines

Researchers report a new strategy for the microbial production of multiple short-chain primary amines via retrobiosynthesis.

17 Jan 2021

Researchers solve the structure, function of mitochondrial sorting and assembly machinery

Mitochondria are vital for the human body as cellular powerhouses: They possess more than 1,000 different proteins, required for many central metabolic pathways.

16 Jan 2021

Certain snakes evolve a unique genetic trick to avoid venomous snake-eating snakes

Certain snakes have evolved a unique genetic trick to avoid being eaten by venomous snakes, according to University of Queensland research.

15 Jan 2021

Computational method uses heat map data to reverse engineer 3D chromosome models

Genome analysis can provide information on genes and their location on a strand of DNA, but such analysis reveals little about their spatial location in relation to one another within chromosomes -- the highly complex, three-dimensional structures that hold genetic information.

15 Jan 2021

Research reveals new details into how myosin transduces energy

A team of biophysicists from the University of Massachusetts Amherst and Penn State College of Medicine set out to tackle the long-standing question about the nature of force generation by myosin, the molecular motor responsible for muscle contraction and many other cellular processes.

14 Jan 2021

Novel compound appears to protect myelin and nerve fibers

A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord.

13 Jan 2021

Medicinal plant-derived compound destroys brain-eating amoeba in lab studies

Primary amoebic meningoencephalitis (PAM), a deadly disease caused by the "brain-eating amoeba" Naegleria fowleri, is becoming more common in some areas of the world, and it has no effective treatment.

13 Jan 2021

Biochemistry

Pancreatic β cell-derived exosomal miR-29s manipulate glucose homeostasis

Marine microalgae could be the solution to world's meat protein shortage

Specific NSAIDs are metabolized by acyl-CoA synthetases leading to liver toxicity

Sloan Kettering Institute researchers offer a new answer to 100-year-old cancer mystery

Scientists discover mechanism for transient memory lapse

Researchers discover potent antifungal agent from attine ant farms

New method reveals how pharmaceuticals induce cancer cell death

Magnetic nanoparticles guide neurite growth in dopaminergic cells

Researchers develop a technique to modify biological polymers with protein-based biochemical messages

Study improves understanding of the chemistry behind potent antibiotic synthesis

CoQ10 supplement could be a valuable complementary therapeutic option for various diseases

Australian scientists develop a new method for rapid synthesis of safe vaccines

Study reveals new way to target cancer’s nutritional needs

Researchers design new biosynthetic pathways for short-chain primary amines

Researchers solve the structure, function of mitochondrial sorting and assembly machinery

Certain snakes evolve a unique genetic trick to avoid venomous snake-eating snakes

Computational method uses heat map data to reverse engineer 3D chromosome models

Research reveals new details into how myosin transduces energy

Novel compound appears to protect myelin and nerve fibers

Medicinal plant-derived compound destroys brain-eating amoeba in lab studies

PromoCell's New GMP Certification - EXCiPACT

Treating post-infectious smell loss in COVID-19 patients

A paper-based sensor for detecting COVID-19

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