Biochemistry

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Researchers modify amide bonds to speed up reactions

In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity, or alkalinity.

29 May 2020

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

28 May 2020

Researchers grow lung organoids from stem cells for Sars-Cov-2 research

A Bochum-based team intends to use organoids from stem cells to study the progression of Sars-CoV-2 infection and to identify antiviral substances.

28 May 2020

New insight into RNA movements can pave way for strategies to treat cancer

Research from Karolinska Institutet published today in Nature shows that an RNA molecule involved in preventing tumour formation can change its structure and thereby control protein production in the cell.

28 May 2020

Simple salt solution can help transport COVID-19 samples to testing laboratories

In a new peer-reviewed study appearing in The Journal of Molecular Diagnostics, published by Elsevier, investigators report that a simple salt solution commonly found in hospitals and clinical laboratories, phosphate buffered saline (PBS), can be used as a medium to reliably transport coronavirus-contaminated specimens to the testing laboratory for periods of up to 18 hours, which is often needed in busy clinical settings.

27 May 2020

Research could help identify disturbances in the body's copper metabolism

In biology it is well-known that every living organism is triggered by the hereditary material or DNA that encodes various protein molecules, which in turn perform all the necessary biological functions and it might seem that nothing else is needed to sustain the life of an organism.

26 May 2020

UZH researchers develop new X-ray contrast agent for high-resolution vascular imaging

Various diseases in humans and animals - such as tumors, strokes or chronic kidney disease - damage the blood vessels. Capillaries, the smallest blood vessels in the body, are particularly affected.

26 May 2020

Minuscule tracking devices give unprecedented peek into how cells change with time

For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning of development.

26 May 2020

Warwick researchers discover how cells activate autophagy genes during fasting

As modern life-styles and high calorie diets drive the UK's obesity levels up, researchers from the University of Warwick have found how cells respond to fasting and activate the process called autophagy, which means a healthier lifestyle can be promoted to help people maintain a healthy body weight.

26 May 2020

Research opens new horizons for studies on potentially health promoting foods

Fermented foods can be a primary source of potentially probiotic lactic acid bacteria (LAB) for the human gut, as is shown in a new international study published in Nature Communications.

25 May 2020

Scientists identify compounds in noxious weed that reduce virulence of Staphylococcus bacteria

Scientists have identified specific compounds from the Brazilian Peppertree -- a weedy, invasive shrub in Florida -- that reduce the virulence of antibiotic-resistant staph bacteria.

22 May 2020

Hydrocarbon bonds may help synthesize large range of novel organic molecules

The most common chemical bond in the living world -- that between carbon and hydrogen -- has long resisted attempts by chemists to crack it open, thwarting efforts to add new bells and whistles to old carbon-based molecules.

22 May 2020

New water-tasting approach could help pinpoint reserves of valuable minerals

Mining companies could more accurately pinpoint reserves of valuable minerals using a new water-tasting approach developed by the national science agency, CSIRO, in research supported by the Minerals Research Institute of Western Australia.

22 May 2020

New metal-free methodology for fluorination of aliphatic hydrocarbon bonds

Researchers from the Muñiz group have published a paper in Angewandte Chemie - International Edition presenting a new metal-free methodology for the photo-catalyzed nucleophilic fluorination of aliphatic hydrocarbon bonds.

21 May 2020

Scientists develop novel flow cytometry technique to quantify protein production in T-cells

A team of scientists from Hollings Cancer Center at the Medical University of South Carolina (MUSC) has developed a novel flow cytometry technique that can, for the first-time, quantify protein production in T-cells.

20 May 2020

Researchers report a new way to stabilize liposomes

For decades, scientists have explored the use of liposomes –– hollow spheres made of lipid bilayers –– to deliver chemotherapy drugs to tumor cells.

20 May 2020

Novel molecular structures developed for desired transcriptional response

Insilico Medicine announces the publication of a new research paper titled "Molecular Generation for Desired Transcriptome Changes With Adversarial Autoencoders" in Frontiers in Pharmacology

20 May 2020

New technique produces pure therapeutic drugs without the associated side effects

Scientists from Hong Kong Baptist University (HKBU) have developed a novel technique that can produce pure therapeutic drugs without the associated side effects.

19 May 2020

A new tool to study and map the intricacies of intercellular signaling

How do cells move? Why do they move? Why do some cancer cells move slowly while others move quickly, causing a cancerous tumor to metastasize and become much more difficult to treat effectively?

18 May 2020

Cigarette smoke spurs the lungs to make more SARS-CoV-2 receptors

New research from CSHL scientists suggests that cigarette smoke spurs the lungs to make more ACE2 (angiotensin-converting enzyme 2), the protein that the coronavirus responsible for COVID-19 grabs and uses to enter human cells.

18 May 2020