Biochemistry

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Innovative probe could deepen our understanding of crucial cellular messenger and pave way for new therapeutic drugs

A ground-breaking study by Loughborough University and the University of Oxford has led to the development of a small molecule probe that could deepen our understanding of a crucial cellular messenger and lead to the development of new therapeutic drugs.

30 May 2023

Using ex vivo gene therapy to fight obesity and diabetes in mice

A scientific team from the University of Barcelona and the CIBERobn has designed a strategy to fight obesity and diabetes in mice through ex vivo gene therapy which consists of implanting cells that have been manipulated and transformed in order to treat a disease.

30 May 2023

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded.

26 May 2023

Japanese natto consumption may help realize a healthy and longer-living society

Health is wealth as the saying goes and new research now shows that it is possible to have a healthy, less stressed society through familiar and inexpensive foods.

26 May 2023

Scientists use AI to identify new antibiotic that could fight drug-resistant infections

Using an artificial intelligence algorithm, researchers at MIT and McMaster University have identified a new antibiotic that can kill a type of bacteria that is responsible for many drug-resistant infections.

25 May 2023

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

In this behind-the-scenes interview, we speak to Dr. Sinead Knight, chair of SLAS Europe 2023, about this years programme, highlighting the key topics and speakers.

From Society for Laboratory Automation and Screening (SLAS) 25 May 2023

Short-chain fatty acids play a beneficial role in the gut-lung axis of aging mice

The gut microbial community structure-; communities of bacteria, viruses and fungi that live in the intestines-; influences the inflammatory response in the lungs of aging mice, according to researchers from the Institute of Functional Anatomy at Charité, the Medical University of Berlin in Germany.

25 May 2023

Oxygen restriction associated with longer lifespan in lab mice

For the first time, researchers have shown that reduced oxygen intake, or "oxygen restriction", is associated with longer lifespan in lab mice, highlighting its anti-aging potential.

24 May 2023

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

$Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride$

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

For pharmaceuticals, knowing the chemical composition is not enough-;molecular geometry and crystal structure also play an important role in a drug's activity.

23 May 2023

Honokiol inhibits replication of SARS-CoV-2 in several cell types

A compound called honokiol, which is found in the bark of multiple species of magnolia tree, inhibits replication of SARS-CoV-2 virus in several types of cells, according to a team of researchers in the Netherlands.

22 May 2023

Exploring how and why nitrate has contrasting potential risks and benefits

Despite our understanding of nutrition expanding remarkably in recent times, few aspects of our diet continue to confuse and divide the experts like nitrate.

22 May 2023

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Researchers from Rice University and Baylor College of Medicine are hoping a first-of-its-kind "glyco-immune" checkpoint inhibitor could be the key to stopping bone cancer metastasis for breast cancer survivors.

19 May 2023

Low-cost, recyclable powder uses sunlight to kill thousands of waterborne bacteria

At least 2 billion people worldwide routinely drink water contaminated with disease-causing microbes.

18 May 2023

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to their anti-inflammatory and immunosuppressant action.

18 May 2023

Biochemistry

Innovative probe could deepen our understanding of crucial cellular messenger and pave way for new therapeutic drugs

Using ex vivo gene therapy to fight obesity and diabetes in mice

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Japanese natto consumption may help realize a healthy and longer-living society

Scientists use AI to identify new antibiotic that could fight drug-resistant infections

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences

Short-chain fatty acids play a beneficial role in the gut-lung axis of aging mice

Oxygen restriction associated with longer lifespan in lab mice

Looking at cancer drugs to help put the brakes on classic indicators of aging

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

Honokiol inhibits replication of SARS-CoV-2 in several cell types

Exploring how and why nitrate has contrasting potential risks and benefits

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Low-cost, recyclable powder uses sunlight to kill thousands of waterborne bacteria

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Melanin structure discovery brings scientists one step closer to developing ultra-protective sunscreen

NIR spectroscopy offers fast, easy, inexpensive way to detect food allergens

Using synthetic peptides for inflammatory disease diagnosis

Study establishes a mechanistic link between obesity and oral cancer immune escape

Researchers discover how the A. baumannii can survive harsh environments

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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