Biochemistry

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New study opens unprecedented opportunities for bioengineering vaccine adjuvants

A valuable molecule sourced from the soapbark tree and used as a key ingredient in vaccines, has been replicated in an alternative plant host for the first time, opening unprecedented opportunities for the vaccine industry.

26 Jan 2024

Immune component of breast milk shapes the gut environment of infant mice

An immune component of breast milk known as the complement system shapes the gut environment of infant mice in ways that make them less susceptible to certain disease-causing bacteria, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

24 Jan 2024

Moffitt researchers develop novel reagent for efficient synthesis of sulfur-containing drug candidates

During the past decade, there has been significant development of new sulfur containing compounds that are used in various industries, including pharmaceuticals and agricultural products.

22 Jan 2024

New targeted therapy eliminates cancer with zero side effects

Johannes Karges develops anti-cancer agents that work in a targeted manner, rather than adversely affecting the entire body.

18 Jan 2024

Unlocking protein secrets: X-ray crystallography reveals hidden shapes

Proteins do the heavy lifting of performing biochemical functions in our bodies by binding to metabolites or other proteins to complete tasks.

12 Jan 2024

Disease-causing bacteria use molecular "barcode" to distinguish between beneficial and toxic molecules

Researchers at McMaster University have discovered a molecular "barcode" system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.

8 Jan 2024

Researchers identify microbial enzyme responsible for making urine yellow

Researchers at the University of Maryland and National Institutes of Health have identified the microbial enzyme responsible for giving urine its yellow hue, according to a new study published in the journal Nature Microbiology on January 3, 2024.

3 Jan 2024

Understanding acylspermidines' secrets could lead to treatments for various diseases

In a significant advancement in the field of biochemistry, scientists at the Boyce Thompson Institute (BTI) and Cornell University have uncovered new insights into a family of metabolites, acylspermidines, that could change how we understand aging and fight diseases.

2 Jan 2024

Scientists take a major step towards realizing synthetic CO2 fixing pathways in living cells

Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2).

2 Jan 2024

Catenane magic: Boosting protein stability and resilience with interlocking rings

This study is led by Prof. Wen-Bin Zhang (College of Chemistry and Molecular Engineering, Peking University & Beijing Academy of Artificial Intelligence) and Dr. Jing Fang (College of Chemistry and Molecular Engineering, Peking University).

29 Dec 2023

New method designs high-affinity, orally bioavailable peptides

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy.

28 Dec 2023

Research reveals how "forever chemicals" damage DNA at the molecular level

Recent research published in the journal Eco-Environment & Health (Volume 2, 2023) reveals groundbreaking insights into how typical PFAAs accelerate the degradation of DNA.

26 Dec 2023

Fox urine compound effectively repels flies through multisensory activation

Crop damage in agriculture and the transmission of vector-borne diseases by insect pests have become worldwide threat nowadays.

25 Dec 2023

New family of polymers can kill bacteria without inducing antibiotic resistance

Antibiotic-resistant bacteria have become a rapidly growing threat to public health. Each year, they account for more than 2.8 million infections, according to the U.S. Centers for Disease Control and Prevention.

22 Dec 2023

New mechanism that regulates dietary lipid processing by the intestine revealed

The maintenance of a balanced lipid homeostasis is critical for our health. While consumption of excessive amounts of fatty foods contributes to metabolic diseases such as obesity and atherosclerosis, fat is an indispensable component of our diet.

20 Dec 2023

TMDU researchers develop novel method to identify protein-protein binding interfaces

Proteins are building blocks of our bodies, but they do not work solo. They form partners to facilitate in different biological processes that keep us going.

20 Dec 2023

Key Charpentier/Doudna CRISPR patent upheld by Japanese Patent Office

Patent JP6692856 upheld for second time in response to invalidation challenge.

19 Dec 2023

Oxidized amino acids signal damaged photosynthesis proteins for repair

Photosynthesis refers to the fundamental biological process of the conversion of light energy into chemical energy by chlorophyll (a green pigment) containing plants.

18 Dec 2023

Study unlocks muscle-boosting algae magic

With more of us looking for alternatives to eating animals, new research has found a surprising environmentally friendly source of protein – algae.