Biochemistry

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New compound shows promise as a more effective treatment for schistosomiasis

A newly developed compound is showing promise in animal studies as a more effective treatment for human schistosomiasis, an understudied tropical disease caused by parasitic worms.

25 Mar 2024

Prolonged inactivity affects cholesteryl esters differently depending on age

A new study examining cholesteryl esters suggests that periods of prolonged inactivity may affect people differently depending on their age.

25 Mar 2024

New compound extracted from African catfish skin mucas exhibits powerful antibacterial properties

Scientists report they have extracted a compound with powerful antibacterial properties from the skin of farmed African catfish.

25 Mar 2024

Revolutionizing cysteine-rich peptide production for drug discovery

Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way.

22 Mar 2024

New "fusion sites" enable faster and more targeted drug development

Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products from Bacteria.

22 Mar 2024

Study illuminates untapped potential of the shrub sea buckthorn as a source of natural antioxidants

New research, published in SCI's Journal of the Science of Food and Agriculture illuminates the untapped potential of the shrub sea buckthorn as a rich source of natural antioxidants in North America.

21 Mar 2024

Study challenges previously held views on brain preservation in archaeology

Soft tissue preservation in the geological record is relatively rare, and, except where deliberate intervention halts the process of decay (like embalming or freezing), the survival of entire organs is particularly unusual.

21 Mar 2024

Researchers create a method to determine psilocybin and psilocin potency in mushrooms

Since the 1970s, the federal government has listed the active ingredients in mushrooms-;psilocybin and psilocin-;as illegal and having no accepted medical use.

18 Mar 2024

Breakthrough research uncovers neural basis of odor perception

Scents, such as coffee, flowers, or freshly-baked pumpkin pie, are created by odor molecules released by various substances and detected by our noses.

18 Mar 2024

New custom-designed proteins can efficiently reach intramembrane targets

Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed proteins that can efficiently reach these "intramembrane" targets.

13 Mar 2024

New PET radiotracer distinguishes diseased tissues based on fructose metabolism

A new PET radiotracer can differentiate diseased tissues from healthy tissues based on fructose metabolism, according to new research published in the March issue of The Journal of Nuclear Medicine.

8 Mar 2024

U-M research offers a new path forward in the development of anti-HIV drugs

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.

8 Mar 2024

Deep-learning-enhanced mass spectrometry for biochemical mapping of the brain

Beckman Institute for Advanced Science and Technology researchers Jonathan Sweedler, a professor of chemistry, and Fan Lam, a professor of bioengineering, outlined how spatial omics technologies can reveal the molecular intricacy of the brain at different scales.

6 Mar 2024