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Review explores patients' and physicians' experiences with remote consultations in primary care

According to the Royal College of General Practitioners, at the peak of the Covid-19 pandemic, the ways in which patients accessed their GP reversed from around 70% face-to-face and 30% by phone, video or online pre-pandemic to around 30% face-to-face and 70% remote.

17 Jan 2022

Researchers investigate the role of a key component of the circadian clock in heart disease

Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition.

17 Jan 2022

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

A team of researchers assessed the immune response after administering a SARS-COV-2 vaccine in immuno-compromised subjects who are potentially at an increased risk to experience severe COVID-19 and inadequate response to SARS-CoV2 vaccination.

17 Jan 2022

Mental health of intensive care unit staff adversely impacted during COVID-19 pandemic

In a new study, a team of researchers surveyed the prevalence of mental health disorders in intensive care unit workers from England during the COVID-19 pandemic.

17 Jan 2022

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Researchers demonstrated that this splice variant is likely to be the single nucleotide polymorphism responsible for the association at this locus.

17 Jan 2022

Seroepidemiologic surveys for assessment of the COVID-19 pandemic in Japan

In a new study, a team of researchers demonstrated that Japan had witnessed a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant-induced endemic between August and December 2021.

17 Jan 2022

Framework for understanding cross-country spread of COVID-19 in the context of the globally interconnected economy

A study published in Scientific Reports uses a three-dimensional conceptual model to examine COVID-19's global spatiotemporal dissemination.

17 Jan 2022

Study evaluates acute and long-term adverse events following immunization with COVID-19 Moderna vaccine

In a new study, a team of researchers conducted a case-control study at a mass vaccination center in Japan to evaluate acute and long-term adverse events following immunization (AEFI) with coronavirus disease 2019 (COVID-19) Moderna vaccine.

17 Jan 2022

Researchers construct models to predict SARS-CoV-2 mutable and constrained positions

In a study published in PNAS, researchers have attempted to create a model that can successfully predict which positions are likely to mutate in the future.

17 Jan 2022

Better global health equality could prevent emergence of future SARS-CoV-2 variants of concern

In a new study, researchers used a simple phenomenological model to investigate the role of immunocompromised hosts in SARS-CoV-2 antigenic development.

17 Jan 2022

Study suggests vaccinated Omicron cases are unlikely to shed infectious virus 10 days after diagnosis or symptom onset

Researchers have been investigating the Omicron epidemic in Japan and have recently released an early report on the infectious period of the disease.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

A new paper discusses the appearance of quasi-species in a single host with prolonged infection, with different rates of infectivity and sensitivity to neutralization by antibodies elicited by the Pfizer vaccine or those present in convalescent plasma.

17 Jan 2022

Study reveals aerosol transmission of SARS-CoV-2 via floor drains

A new study investigated COVID-19 cases in an apartment complex in South Korea and explored the possibility of aerosol transmission without direct contact between infected individuals with the help of molecular phylogenetic analysis and epidemiological surveillance.

17 Jan 2022

Nine-month survey of COVID-19 vaccine effectiveness in North Carolina

A new paper reports increased breakthrough infections with SARS-CoV-2, the agent behind the ongoing COVID-19 pandemic.

17 Jan 2022

Study investigates whether immune responses to BNT162b2 vaccine differ in subjects with and without prior SARS-CoV-2 infection

A new paper published in the journal JCI Insight reports on the differential levels of immunity achieved in those with and without a history of prior infection with the virus following one and two doses of the earliest vaccines to be approved for emergency use.

17 Jan 2022

Rapid antigen tests for SARS-CoV-2 have low overall rate of false-positive results

A timely new study investigated the incidence of false-positive results in a large sample of rapid antigen tests used to serially screen asymptomatic workers throughout Canada.

17 Jan 2022

Protein biomarkers in urine could be used to diagnose concussion and monitor recovery

Concussion can be frustratingly hard to diagnose and track. The injury doesn't show up on routine brain scans, and there is no definitive diagnostic test. It's usually diagnosed based on symptoms, and, in athletes, comparison with baseline testing if it was done. But concussion symptoms are non-specific, unreliable, and easily influenced by emotions.

17 Jan 2022

Free-energy principle can explain how neural networks are optimized for efficiency

The RIKEN Center for Brain Science (CBS) in Japan, along with colleagues, has shown that the free-energy principle can explain how neural networks are optimized for efficiency.

16 Jan 2022

Discovery opens up the possibility of pursuing new therapies for FOP

Fibrodysplasia ossificans progressiva (FOP) is a rare disease characterized by extensive bone growth outside of the normal skeleton that pre-empts the body's normal responses to even minor injuries. It results in what some term a "second skeleton," which locks up joint movement and could make it hard to breathe.

16 Jan 2022

Medical Research News

Review explores patients' and physicians' experiences with remote consultations in primary care

Researchers investigate the role of a key component of the circadian clock in heart disease

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

Mental health of intensive care unit staff adversely impacted during COVID-19 pandemic

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Seroepidemiologic surveys for assessment of the COVID-19 pandemic in Japan

Framework for understanding cross-country spread of COVID-19 in the context of the globally interconnected economy

Study evaluates acute and long-term adverse events following immunization with COVID-19 Moderna vaccine

Researchers construct models to predict SARS-CoV-2 mutable and constrained positions

Better global health equality could prevent emergence of future SARS-CoV-2 variants of concern

Study suggests vaccinated Omicron cases are unlikely to shed infectious virus 10 days after diagnosis or symptom onset

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

Study reveals aerosol transmission of SARS-CoV-2 via floor drains

Nine-month survey of COVID-19 vaccine effectiveness in North Carolina

Study investigates whether immune responses to BNT162b2 vaccine differ in subjects with and without prior SARS-CoV-2 infection

Rapid antigen tests for SARS-CoV-2 have low overall rate of false-positive results

Protein biomarkers in urine could be used to diagnose concussion and monitor recovery

Free-energy principle can explain how neural networks are optimized for efficiency

Discovery opens up the possibility of pursuing new therapies for FOP

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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