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Inhibition of SARS-CoV-2 helicase by single DNA lesions

In a paper, the impact of specific DNA lesions is investigated regarding the unwinding activity of NSP13.

18 Oct 2021

Researchers identify protein that plays a key role in how the brain regulates appetite and metabolism

Researchers from the Okinawa Institute of Science and Technology Graduate University have identified a protein that plays a key role in how the brain regulates appetite and metabolism.

18 Oct 2021

Researchers report long-lasting effects of gene therapy in children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder.

18 Oct 2021

New research focuses on better understanding of lupus in Black women

Nine out of 10 patients with systemic lupus erythematosus - the autoimmune disease also known as SLE - are females.

18 Oct 2021

Coronavirus vaccines and prior infections can provide broad immunity against similar viruses

Northwestern Medicine scientists have shown for the first time that coronavirus vaccines and prior coronavirus infections can provide broad immunity against other, similar coronaviruses. The findings build a rationale for universal coronavirus vaccines that could prove useful in the face of future epidemics.

18 Oct 2021

Many people perceive the use of facial analytics in healthcare settings as a potential privacy threat

Uses of facial images and facial recognition technologies – to unlock a phone or in airport security – are becoming increasingly common in everyday life. But how do people feel about using such data in healthcare and biomedical research?

18 Oct 2021

People with obesity overrepresented among COVID-19 patients receiving intensive care

People with obesity were overrepresented among adults in Sweden receiving intensive care for COVID-19 during the first wave of the pandemic. Just over 39 percent had obesity, compared with some 16 percent in the population.

18 Oct 2021

Research indicates that mRNA vaccine-induced T cells respond robustly to new SARS-CoV-2 variants

To address the gaps in the knowledge, a team of researchers from the University of California and the Gladstone Institute of Virology conducted 39-parameter phenotyping by cytometry by time of flight (CyTOF) on 33 longitudinal specimens from 11 mRNA-vaccinated individuals, of which six had previously been infected and recovered from COVID-19.

18 Oct 2021

New study focuses on getting shy children to face their fears

Getting shy children to 'face their fears' and coaching parents in exposure therapy is the focus of a new study at The University of Queensland.

18 Oct 2021

People with higher genetic risk for clinical depression more likely to experience physical symptoms

People with higher genetic risk of clinical depression are more likely to have physical symptoms such as chronic pain, fatigue and migraine, University of Queensland researchers have found.

18 Oct 2021

New class of CXCR4 antagonists could prevent airway inflammation and atopic dermatitis

Aberrant CXCR4/CXCL12 signaling is involved in many pathophysiological processes such as cancer and inflammatory diseases. A natural fragment of serum albumin, named EPI-X4, has previously been identified as endogenous peptide antagonist andinverse agonistof CXCR4 and is a promising compound for the development of improved analogues for the therapy of CXCR4-associated diseases.

18 Oct 2021

Engineered 3D scaffolds of human brown adipose tissue as a new therapeutic strategy for obesity and diabetes

A group of researchers from various institutes in the USA addressed the limitations of BAT therapy by transplanting a low dose of brown adipocytes (BAs) without Matrigel to determine if this could alleviate high-fat diet-induced OB, metabolic symptoms, and T2DM in mice.

18 Oct 2021

Study finds connection between austerity measures and increased mortality in England

Central government austerity measures since 2010 are linked to tens of thousands more deaths than expected, finds research published in the online journal BMJ Open on the joint impact of social care, public health, and healthcare spends on death rates before and after 2010.

18 Oct 2021

Delta and Delta Plus infect lung cells with higher efficiency than the original virus, research shows

The emergence of new SARS-CoV-2 variants that can spread rapidly and undermine vaccine-induced immunity threatens the end of the COVID-19 pandemic. The delta variant (B.1.617.2) emerged in India and subsequently spread globally within a short time period. Also in Germany, almost all recent infections are due to this variant.

18 Oct 2021

Study explores the likelihood of inappropriate decisions by physicians during delivery

Clinical decisions made in the delivery setting as to whether to employ vaginal delivery or cesarean section are often made under high pressure, and with great uncertainty, and have serious consequences for mother and baby.

18 Oct 2021

Does vitamin D deficiency increase the risk of SARS-CoV-2 infections?

A recent study posted to the medRxiv* preprint server attempted to understand the relationship between vitamin D levels and COVID-19 by studying a population of UK healthcare workers who exhibited symptoms for COVID-19.

17 Oct 2021

Serologic testing algorithm to detect disparities in SARS-CoV-2 infection prevalence and vaccination uptake

A new study recently published on the medRxiv* preprint server demonstrates the use of a serological testing algorithm for identifying disparities in infection rates and vaccine uptake amongst the study population to enable public health interventions.

17 Oct 2021

Fibrin immunotherapy may resolve blood clotting induced by SARS-CoV-2

A group of researchers from the United States discovered that the spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can induce the formation of highly inflammatory blood clots amenable to neutralization by a fibrin-targeting monoclonal antibody – opening the door for a completely new strategy to reduce thrombotic inflammation in coronavirus disease 2019 (COVID-19).

17 Oct 2021

Mix-and-match booster shots beneficial in boosting SARS-CoV-2 immunity

Should you get a second dose of the same vaccine if you’ve received the one-dose Johnson & Johnson shot? According to new clinical trial results published on the preprint medRxiv* server, a booster shot of a messenger RNA (mRNA) vaccine may increase your chances of neutralizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Oct 2021

Researchers identify common side effects of three COVID-19 vaccines

COVID-19 vaccines remain the best tool in the pandemic toolbox against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). But they are not perfect; reports have surfaced of mild to severe side effects after vaccination. A new study from researchers in the Lampe & Company GmbH & Co. KG compared the severity of adverse events from each coronavirus vaccine.

17 Oct 2021

Medical Research News

Inhibition of SARS-CoV-2 helicase by single DNA lesions

Researchers identify protein that plays a key role in how the brain regulates appetite and metabolism

Researchers report long-lasting effects of gene therapy in children with deadly immune disorder

New research focuses on better understanding of lupus in Black women

Coronavirus vaccines and prior infections can provide broad immunity against similar viruses

Many people perceive the use of facial analytics in healthcare settings as a potential privacy threat

People with obesity overrepresented among COVID-19 patients receiving intensive care

Research indicates that mRNA vaccine-induced T cells respond robustly to new SARS-CoV-2 variants

New study focuses on getting shy children to face their fears

People with higher genetic risk for clinical depression more likely to experience physical symptoms

New class of CXCR4 antagonists could prevent airway inflammation and atopic dermatitis

Engineered 3D scaffolds of human brown adipose tissue as a new therapeutic strategy for obesity and diabetes

Study finds connection between austerity measures and increased mortality in England

Delta and Delta Plus infect lung cells with higher efficiency than the original virus, research shows

Study explores the likelihood of inappropriate decisions by physicians during delivery

Does vitamin D deficiency increase the risk of SARS-CoV-2 infections?

Serologic testing algorithm to detect disparities in SARS-CoV-2 infection prevalence and vaccination uptake

Fibrin immunotherapy may resolve blood clotting induced by SARS-CoV-2

Mix-and-match booster shots beneficial in boosting SARS-CoV-2 immunity

Researchers identify common side effects of three COVID-19 vaccines

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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