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SARS-CoV-2 infection can produce self-attacking autoantibodies

Infection with the virus that causes COVID-19 can trigger an immune response that lasts well beyond the initial infection and recovery - even among people who had mild symptoms or no symptoms at all, according to Cedars-Sinai investigators.

30 Dec 2021

Booster doses of mRNA vaccines improve humoral immunogenicity in patients with inflammatory bowel disease

Researchers evaluated the humoral immunogenicity of a third COVID-19 mRNA vaccine dose in patients with inflammatory bowel disease.

30 Dec 2021

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Drug-induced liver injury (DILI) is an adverse reaction to ingesting a drug, which can appear both in developmental stages, in their clinical use and even after being approved as a drug.

30 Dec 2021

Orphanhood decreases with the availability of antiretroviral therapy and male circumcision

Researchers at Columbia University Mailman School of Public Health found marked decreases in orphanhood particularly double orphanhood, among adolescents in Rakai, Uganda, corresponding with the availability of antiretroviral therapy (ART) beginning in 2004 and of male medical circumcision in 2007.

30 Dec 2021

Once-a-day antiretroviral medicine for children proven to be more effective at suppressing HIV

A once-a-day antiretroviral medicine that is low-cost and easy for children to take is also more effective at suppressing HIV than standard treatments, according to a global trial led by researchers at UCL.

30 Dec 2021

Growth-friendly surgeries have more complications than spinal fusion in kids treated with severe scoliosis

A Michigan Medicine study found that preadolescent children with severe neuromuscular scoliosis who are treated with growth-friendly surgery prior to spinal fusion have more complications and unplanned subsequent surgeries than those who only have the spinal fusion.

30 Dec 2021

Higher rates of preeclampsia found among Black women born in the U.S. than foreign-born counterparts

A novel analysis of medical records for a racially diverse group of more than 6,000 women has added to evidence that some combination of biological, social and cultural factors — and not race alone — is likely responsible for higher rates of preeclampsia among Black women born in the United States compared with Black women who immigrated to the country.

30 Dec 2021

Healthy dietary habits help reduce risk of gestational diabetes mellitus in pregnant women

Obesity is a significant risk factor for developing gestational diabetes mellitus, and an increasing number of pregnant women are overweight or obese. Dietary habits have an impact on both obesity and the onset of gestational diabetes mellitus.

30 Dec 2021

Black men with prostate cancer may have improved response to radiation therapy than white men

UCLA Jonsson Comprehensive Cancer Center researchers leading a meta-analysis of seven randomized trials found an "unexpected result": Although Black men appeared to have more aggressive disease when they enrolled in clinical trials of radiation therapy for prostate cancer, their treatment outcomes and disease-specific outcomes were better than those of their white counterparts.

30 Dec 2021

An integrated computational methodology for COVID drug prioritization

Researchers recently published a study in the journal Briefings in Bioinformatics wherein they integrated multiple bioinformatics and cheminformatics-based methods to prioritize drugs for the treatment of COVID-19.

29 Dec 2021

Omicron will outcompete Delta variant for next 4-5 months globally: Genome study

A new study published in the pre-print server medRxiv* hypothesized that the emergence of more immune invasive or transmissible variants of SARS-CoV-2 was associated with increased genetic distinctiveness from the original or previous strains.

29 Dec 2021

Rapid antigen tests show lower sensitivity for Omicron than for earlier SARS-CoV-2 variants

Researchers carried out an analytical susceptibility test with cultured SARS-CoV-2 Omicron variant in seven antigen-detecting rapid diagnostic (Ag-RDTs).

29 Dec 2021

Omicron analysis shows no clear evidence for increased virulence or lethality

Researchers conducted a genomic sequencing and epidemiological correlation analysis of the SARS-CoV-2 Omicron variant.

29 Dec 2021

At least 3 exposures to vaccine or virus needed for minimum protection against SARS-CoV-2 Omicron

Researchers determine the serum neutralizing and binding activity against the SARS-CoV-2 Omicron variant in individuals with different levels of immunity.

29 Dec 2021

MRNA boosters shown to increase protection against SARS-CoV-2 Omicron

Researchers evaluate vaccine effectiveness against SARS-CoV-2 Omicron and Delta variants.

29 Dec 2021

BNT162b2 booster restores protection following waning of the 2-dose vaccine

Researchers assess the real-world effectiveness of a third booster dose of the Pfizer-BioNTech BNT162b2 vaccine against the initial two-dose regimen.

29 Dec 2021

COVID mRNA vaccines show diminished neutralization responses against Omicron

Researchers report an overview of antibody neutralization by all currently approved vaccines against the SARS-CoV-2 Omicron, Beta, and Delta VOCs.

29 Dec 2021

Exploring the importance of selenium in COVID-19 patients

In a new study, researchers reviewed research on the role that selenium could play in protecting individuals against coronavirus disease 2019.

29 Dec 2021

Researchers use rapid antigen testing to identify optimum isolation scenarios in COVID-19 infection

In a new study, researchers have been modeling different isolation scenarios to identify the most effective methods.

29 Dec 2021

Researchers suggest hybrid convalescent plasma therapy neutralizes the omicron variant

New research suggests convalescent plasma from unvaccinated donors is not effective against the Omicron variant, however, “hybrid” convalescent plasma from donors who recovered from COVID-19 infection and are vaccinated provides considerable antibody protection.

29 Dec 2021

Medical Research News

SARS-CoV-2 infection can produce self-attacking autoantibodies

Booster doses of mRNA vaccines improve humoral immunogenicity in patients with inflammatory bowel disease

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Orphanhood decreases with the availability of antiretroviral therapy and male circumcision

Once-a-day antiretroviral medicine for children proven to be more effective at suppressing HIV

Growth-friendly surgeries have more complications than spinal fusion in kids treated with severe scoliosis

Higher rates of preeclampsia found among Black women born in the U.S. than foreign-born counterparts

Healthy dietary habits help reduce risk of gestational diabetes mellitus in pregnant women

Black men with prostate cancer may have improved response to radiation therapy than white men

An integrated computational methodology for COVID drug prioritization

Omicron will outcompete Delta variant for next 4-5 months globally: Genome study

Rapid antigen tests show lower sensitivity for Omicron than for earlier SARS-CoV-2 variants

Omicron analysis shows no clear evidence for increased virulence or lethality

At least 3 exposures to vaccine or virus needed for minimum protection against SARS-CoV-2 Omicron

MRNA boosters shown to increase protection against SARS-CoV-2 Omicron

BNT162b2 booster restores protection following waning of the 2-dose vaccine

COVID mRNA vaccines show diminished neutralization responses against Omicron

Exploring the importance of selenium in COVID-19 patients

Researchers use rapid antigen testing to identify optimum isolation scenarios in COVID-19 infection

Researchers suggest hybrid convalescent plasma therapy neutralizes the omicron variant

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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