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Specific leukemia gene mutations exert divergent effects on DNA repair and sensitivity to PARP Inhibitors

In a recent study published in Cancer Research, researchers from Fels Cancer Institute for Personalized Medicine at the Lewis Katz School of Medicine at Temple University and Fox Chase Cancer Center identified specific leukemia gene mutations and the mechanisms by which they regulate DNA repair and respond to PARP inhibitors.

13 Aug 2021

Study examines the relationship between air pollution and labor productivity

Recent studies have highlighted the link between high levels of air pollution and poor health; for example, even short exposure to air pollutants can increase the risk of respiratory infections, heart disease and even lung cancer.

13 Aug 2021

Scientists document person-to-person transmission of antimicrobial-resistant pneumonic plague

Although the world is focused on the COVID-19 pandemic, there are many other dangerous pathogens still out there, like Yersinia pestis, which causes plague – the deadly disease that killed tens of millions of people during the infamous Black Death in the 14th century.

13 Aug 2021

Metabolic changes take an unexpected path through the human life course

An international research team studying data from thousands of people worldwide has shown that people's metabolisms peak earlier and decline later in life than previously thought.

13 Aug 2021

Study: 90% of children with ADHD continue to experience residual symptoms into young adulthood

Most children diagnosed with attention deficit hyperactive disorder (ADHD) don't outgrow the disorder, as widely thought.

13 Aug 2021

Study finds comparatively less marijuana use in cancer patients than the general public

Last month, three states – Virginia, South Dakota, and Connecticut – joined the ranks of more than a dozen others that have legalized marijuana – also known as cannabis – for recreational use. Yet, despite these changing laws and growing social acceptance of the drug, a new study finds that use is still lower among cancer patients.

13 Aug 2021

Discovery of highly potent neutralizing monoclonal antibodies against SARS-CoV-2

A new study published in the journal Nature Communications has reported two neutralizing antibodies, namely, nCoVmab1 and nCoVmab2, which are potent against SARS-CoV-2.

13 Aug 2021

How replication and recombination contribute to emergence of SARS-CoV-2 variants

The coronavirus disease 2019 (COVID-19) pandemic has been caused by the rapid outbreak of a novel coronavirus, namely, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 was first reported in late December 2019 in Wuhan, China. Since then, the virus has already claimed more than 4.3 million lives worldwide.

13 Aug 2021

Study provides important insights into human metabolism

Metabolism and total energy expenditure change throughout our lives, and now a new study documents a series of distinct, related changes in unprecedented detail.

13 Aug 2021

Study highlights the significance of screening for pre-cancerous Barrett’s esophagus

Abnormal cells that go on develop into oesophageal cancer – cancer that affects the tube connecting the mouth and stomach – start life as cells of the stomach, according to scientists at the University of Cambridge.

13 Aug 2021

Research debunks myth that COVID vaccination promotes mutations

A study conducted by researchers at the University of Maryland, USA, has highlighted the importance of coronavirus disease 2019 (COVID-19) vaccination in reducing the frequency of mutations in the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

13 Aug 2021

SARS-CoV-2 variants containing L452R spike mutation more resistant to antibody-mediated neutralization

A team of scientists from Frankfurt, Germany, has recently explored the efficacy of vaccine- or infection-induced antibodies and therapeutic monoclonal antibodies in neutralizing kappa and delta variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 Aug 2021

Camelid nanobody anti-SARS-CoV-2 drug candidates

In a research paper recently published in the journal eLife, researchers from several US institutions have developed a nanobody-based candidate drug that effectively prevents and suppresses severe SARS-CoV-2 infection in animals.

12 Aug 2021

Study finds cognitive safety of ketamine and esketamine for patients with treatment-resistant depression

Used for the treatment of depression that does not respond to standard antidepressant medications, the anesthesia drug ketamine – and the related drug esketamine, recently approved for depression treatment – has no important adverse effects on memory, attention, or other cognitive processes, concludes a systematic review of medical research in the September/October issue of Harvard Review of Psychiatry.

12 Aug 2021

Optical nanoscopy reveals how SARS-CoV-2 infection alters human airway cells

How do viruses reorganize host cells with spatial and molecular specificity? Researchers from the Netherlands provided new insights in a recent study posted to the bioRxiv* preprint server, where they use optical nanoscopy to look at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-triggered changes in primary human airway cells.

12 Aug 2021

Metabolism peaks much earlier and starts to decline later than you might think

Most of us remember a time when we could eat anything we wanted and not gain weight. But a new study suggests your metabolism, the rate at which you burn calories, actually peaks much earlier and starts its inevitable decline later than you might think.

12 Aug 2021

Temple researchers receive $1.25M NIH grant to advance understanding of neurodegenerative diseases

Like wear and tear that causes electrical systems to short circuit, neurons in the human nervous system are susceptible to degenerative processes that disrupt the flow of information.

12 Aug 2021

Yale perspective highlights new breakthrough therapies to treat non-small cell lung cancer

A new publication by Yale Cancer Center highlights recent breakthrough therapies developed to treat non-small cell lung cancer (NSCLC).

12 Aug 2021

Researchers map the impact of Covid-19 on the mental well-being of Israelis

During the six weeks between the end of the first COVID-19 outbreak in Israel and the beginning of the second one (late April to early June of 2020), researchers at the Weizmann Institute of Science initiated a study that encompassed more than 12,000 responses from nearly 5,000 respondents to digital questionnaires, in an attempt to assess and understand the mental toll of the pandemic on the country's adult population.

12 Aug 2021

Immunotherapy pairs ultrasound with immune cells to destroy tumors without toxic side effects

Bioengineers at the University of California San Diego have developed a cancer immunotherapy that pairs ultrasound with cancer-killing immune cells to destroy malignant tumors while sparing normal tissue.

12 Aug 2021

Medical Research News

Specific leukemia gene mutations exert divergent effects on DNA repair and sensitivity to PARP Inhibitors

Study examines the relationship between air pollution and labor productivity

Scientists document person-to-person transmission of antimicrobial-resistant pneumonic plague

Metabolic changes take an unexpected path through the human life course

Study: 90% of children with ADHD continue to experience residual symptoms into young adulthood

Study finds comparatively less marijuana use in cancer patients than the general public

Discovery of highly potent neutralizing monoclonal antibodies against SARS-CoV-2

How replication and recombination contribute to emergence of SARS-CoV-2 variants

Study provides important insights into human metabolism

Study highlights the significance of screening for pre-cancerous Barrett’s esophagus

Research debunks myth that COVID vaccination promotes mutations

SARS-CoV-2 variants containing L452R spike mutation more resistant to antibody-mediated neutralization

Camelid nanobody anti-SARS-CoV-2 drug candidates

Study finds cognitive safety of ketamine and esketamine for patients with treatment-resistant depression

Optical nanoscopy reveals how SARS-CoV-2 infection alters human airway cells

Metabolism peaks much earlier and starts to decline later than you might think

Temple researchers receive $1.25M NIH grant to advance understanding of neurodegenerative diseases

Yale perspective highlights new breakthrough therapies to treat non-small cell lung cancer

Researchers map the impact of Covid-19 on the mental well-being of Israelis

Immunotherapy pairs ultrasound with immune cells to destroy tumors without toxic side effects

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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