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Long-held theory of cancer-induced immune suppression requires revision, study says

Many cancers produce an enzyme called IDO that suppresses immune system activity, but the long-held hypothesis of how this mechanism operates requires revision, according to a study published in Clinical Cancer Research.

29 Sep 2021

People with asymmetric brain arteries have a higher risk of developing aneurysms

It's called a silent killer. Warnings are rare, but of the million people who suffer a ruptured brain aneurysm each year, almost half will die and only a third will recover without disabilities.

29 Sep 2021

Large-scale SARS-CoV-2 spike protein mutants analysis identifies subclonal variants indicative of within-host viral diversity

Researchers have investigated a vast SARS-CoV-2 assembly and NGS data set to detect non-synonymous S protein mutations.

29 Sep 2021

Study finds decline in referrals and procedures for common cardiac interventions after COVID-19

An analysis of healthcare data in Ontario, Canada found a significant decline in referrals and procedures performed for common cardiac interventions after the onset of the COVID-19 pandemic.

29 Sep 2021

Scientists link insulin resistance to increased risk of developing major depressive disorder

Stanford Medicine scientists have linked insulin resistance to an increased risk of developing a major depressive disorder.

29 Sep 2021

Bipolar disorder patients experiencing manic episodes likely to show abnormal brain changes

Patients with bipolar disorder who experience manic episodes are more likely to show abnormal brain changes over time, according to one of the largest longitudinal brain imaging studies in its field to date.

29 Sep 2021

Study finds even individuals with mild COVID-19 suffer from long-COVID

Researchers explored the possible risk factors for the development and persistence of longer post-COVID-19 sequelae.

29 Sep 2021

Study finds correlation between neutralizing antibody titer and reported vaccine efficacy

An observational study compares immune responses against three vaccines.

29 Sep 2021

Vaccine-induced SARS-CoV2 immune responses decline at similar rates as those after infection, study finds

A new preprint describes the causal role of waning antibody titers in decreased antibody persistence at one year.

29 Sep 2021

Universal screening for SARS-CoV-2 among hospitalized patients may be ineffective

Universal screening of all hospital admissions for infection with SARS-CoV-2 is highly inefficient as a screening method in regions with a low prevalence of COVID-19 in the absence of high-risk factors.

29 Sep 2021

Peripheral nerve injuries and severe COVID-19

An interesting new study discusses the occurrence of peripheral nerve injuries in a subset of patients who survived severe COVID-19.

29 Sep 2021

Impact of dairy fats on cardiovascular disease

In our latest interview, we spoke to Dr. Kathy Trieu about the impact of dairy fats on cardiovascular disease.

29 Sep 2021

Defect in the interferon system associated with more severe COVID-19

A component of the human interferon system that activates SARS-CoV-2 cellular defenses appears to be defective in a proportion of humans, new research reports. COVID-19 outcomes were more severe in hospitalized patients who exhibited this immune system deficit, the study shows.

29 Sep 2021

Researchers explore the clinical use of intravenous infusions of ketamine to treat depression

Depression is the most common mental illness as well as the number one cause of disability among people between the ages of 15 and 44. And for millions of sufferers, antidepressants have literally saved lives that could otherwise have been lost to suicide.

29 Sep 2021

Heart healthy adults have lower lifetime risk of type 2 diabetes

Heart healthy middle-aged adults are less likely to develop type 2 diabetes during their lifetime, according to a study published on World Heart Day in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology.

29 Sep 2021

Model predicts SARS-CoV-2 spread in vaccinated vs. unvaccinated populations

A modeling study led by Kuan-lin Huang of the Icahn School of Medicine at Mount Sinai in New York suggests that getting vaccinated and taking preventative measures such as social distancing and mask-wearing is the most effective way to curb the spread of severe acute respiratory coronavirus 2 (SARS-CoV-2).

29 Sep 2021

MRIs found to be cost effective for detecting breast cancer for women with very dense breasts

A new paper in the Journal of the National Cancer Institute, published by Oxford University Press, indicates that MRIs are cost effective for detecting breast cancer for women with very dense breasts detected by mammography.

29 Sep 2021

Research provides the basis for an additional novel immunotherapy for multiple myeloma patients

Oncotarget published "Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma" which reported that Multiple Myeloma patients suffer disease relapse due to the development of therapeutic resistance. Increasing evidence suggests that immunotherapeutic strategies can provide durable responses.

29 Sep 2021

Research finds increases in 'pandemic brain' after COVID-19 lockdowns

Chances are, the COVID-19 pandemic has affected your health — even if you have never been infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). According to new research from Harvard Medical School, the stress of isolation from lockdown and stay-at-home measures is making people sick.

29 Sep 2021

Duke neurobiologists show how the rigors of natural selection and evolution have shaped the retinas

If you wanted to design the most perfect, low-energy, light-detecting device for a future camera or a prosthetic retina, you'd reach for something called 'efficient coding theory,' to set out the array of sensors.

29 Sep 2021

Medical Research News

Long-held theory of cancer-induced immune suppression requires revision, study says

People with asymmetric brain arteries have a higher risk of developing aneurysms

Large-scale SARS-CoV-2 spike protein mutants analysis identifies subclonal variants indicative of within-host viral diversity

Study finds decline in referrals and procedures for common cardiac interventions after COVID-19

Scientists link insulin resistance to increased risk of developing major depressive disorder

Bipolar disorder patients experiencing manic episodes likely to show abnormal brain changes

Study finds even individuals with mild COVID-19 suffer from long-COVID

Study finds correlation between neutralizing antibody titer and reported vaccine efficacy

Vaccine-induced SARS-CoV2 immune responses decline at similar rates as those after infection, study finds

Universal screening for SARS-CoV-2 among hospitalized patients may be ineffective

Peripheral nerve injuries and severe COVID-19

Impact of dairy fats on cardiovascular disease

Defect in the interferon system associated with more severe COVID-19

Researchers explore the clinical use of intravenous infusions of ketamine to treat depression

Heart healthy adults have lower lifetime risk of type 2 diabetes

Model predicts SARS-CoV-2 spread in vaccinated vs. unvaccinated populations

MRIs found to be cost effective for detecting breast cancer for women with very dense breasts

Research provides the basis for an additional novel immunotherapy for multiple myeloma patients

Research finds increases in 'pandemic brain' after COVID-19 lockdowns

Duke neurobiologists show how the rigors of natural selection and evolution have shaped the retinas

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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