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COVID-19 severity is correlated with T cell receptor repertoire signatures

In a new study published in the bioRxiv* preprint server, researchers found that specific TCR sequences predicted the severity of coronavirus disease 2019 (COVID-19) infection. Additionally, there was evidence of increased CDR3 sequences and changes in k-mer motifs for patients with severe illness.

6 Dec 2021

Simple quantitative framework to understand the pathogenesis of severe COVID-19

Researchers from Los Alamos National Laboratory in the United States developed a model to explain why severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections induce high inflammatory levels.

6 Dec 2021

Omicron variant increases risk of SARS-CoV-2 reinfection

New surveillance data from South Africa published in the medRxiv* preprint server suggests that the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omnicron variant has the potential to escape naturally-acquired immunity. The research indicates people who previously recovered from a coronavirus disease 2019 (COVID-19) are at risk for reinfection with the Omicron variant. The results show that the risk of reinfection is greater with the Omicron variant versus Delta and Beta.

6 Dec 2021

New test provides a more objective way to assess negative urgency

If you can't stop saying or doing things that you later regret, here's a diagnostic test for you: Researchers at the University of California, Berkeley, have pioneered a way to better determine when acting on one's worst impulses verges on pathological.

6 Dec 2021

Study reveals the effects of cannabis use on oral microbiome and brain health

More and more states are legalizing marijuana, but little is known about how long-term cannabis use affects the microbes in the oral cavity, known as the oral microbiome.

6 Dec 2021

Disparities in maternal mental health during COVID-19

In new research, scientists studied individuals who gave birth during COVID-19. Using propensity score matching (PSM), they matched those identified as either Black or Latinx with those identified as non-Hispanic white on sociodemographic. This recent study published as a preprint on the medRxiv* server attempts to assess the impact of the COVID-19 pandemic on childbirth-related health outcomes in individuals belonging to Black or Latinx minority groups.

6 Dec 2021

Stress accelerates biological clock, but psychological resilience can help manage the effects

Scientists in recent years have developed ways to measure biological age by tracking chemical changes in DNA that occur naturally as people age but occur at different times in different people.

6 Dec 2021

Antipsychotic drugs associated with increase in risk of breast cancer

Researchers at Washington University School of Medicine in St. Louis have found that many commonly prescribed antipsychotic medications are associated with a significant increase in risk of breast cancer.

6 Dec 2021

Researchers discover clearest evidence to date of how memories form

In a discovery that could one day benefit people suffering from traumatic brain injury, Alzheimer's disease, and schizophrenia, UT Southwestern researchers have identified the characteristics of more than 100 memory-sensitive neurons that play a central role in how memories are recalled in the brain.

6 Dec 2021

Study highlights how telehealth can facilitate treatment for people with opioid use disorder

The majority of individuals with opioid use disorder (OUD) face access barriers to evidence-based treatment.

6 Dec 2021

SARS-CoV-2 S2 immunization as a pan-coronavirus vaccine approach

A new mouse model suggests that prior HCoV-OC43 S immunity primes neutralising antibody responses to otherwise subimmunogenic SARS-CoV-2 S exposure as well as promotes S2-targeting antibody responses.

6 Dec 2021

New research explores midwives' work situation and environment

Midwives report a considerably worse work environment, from several aspects, than people on the Swedish labor market in general.

6 Dec 2021

Novel monoclonal antibody could help revolutionize treatment of children with high-risk neuroblastoma

Survival rates increased about 20% for children with high-risk neuroblastoma enrolled in a St. Jude Children’s Research Hospital clinical trial that included a novel monoclonal antibody produced onsite. The findings appeared today in the Journal of Clinical Oncology.

6 Dec 2021

Lack of computer access in COVID predicts lower mental health among adolescents

A new study discusses adolescent mental health during the pandemic in association with the availability of digital access through computers to do schoolwork.

6 Dec 2021

Study shows COVID booster shots work

A new study investigates uses seven different COVID-19 vaccines as the third dose to boost immunity in vulnerable patients.

6 Dec 2021

SARS-CoV-2 Delta saliva viral load 15 times that of the wild type

Researchers hypothesize that a higher viral load of SARS-CoV-2 Delta variant in saliva contributes to its high transmissibility.

6 Dec 2021

Hospitalization trends and associated factors for COVID in 2.3 million adults in England

Researchers performed a retrospective cohort study to determine risk factors for hospitalization and mortality rates over time among COVID-19 patients.

6 Dec 2021

New marker could lead to better diagnoses of Covid-19

Biomedical scientists at LMU have found a new marker in the blood of Covid-19 patients. It furnishes insights into the course and development of the disease and could lead to better diagnoses.

6 Dec 2021

SARS-CoV-2 virus-like particles elicit potent neutralizing antibody response in variant challenge

Researchers develop a virus-like particle for SARS-CoV-2 based on the co-expression of the spike, membrane, and envelope structural proteins.

6 Dec 2021

Long-term exposure to air pollution linked to metabolic-associated fatty liver disease

Metabolic-associated fatty liver disease (MAFLD) is a growing global health challenge and poses a substantial economic burden. A large-scale epidemiologic study in China has identified links between long-term exposure to ambient air pollution and MAFLD.

6 Dec 2021