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Study: COVID-19 produced more symptoms and complications than seasonal influenza in youths

A new global study of 30-day outcomes in children and adolescents with COVID-19 found that while death was uncommon, the illness produced more symptoms and complications than seasonal influenza.

8 Jun 2021

Chemical engineers devise a simpler process to incorporate hydrophobic drugs into tablets

About 60 percent of drugs on the market have hydrophobic molecules as their active ingredients. These drugs, which are not soluble in water, can be difficult to formulate into tablets because they need to be broken down into very small crystals in order to be absorbed by the human body.

8 Jun 2021

NIH researchers identify novel small molecule inhibitors of SARS-CoV-2 variants

A team of scientists from the National Institutes of Health (NIH), USA, has recently identified six novel small molecule inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants. The study is currently available on the bioRxiv* preprint server.

8 Jun 2021

New technology can explain the effect of genetic factors on brain structure, function

Liang Zhan, assistant professor of electrical and computer engineering at Pitt's Swanson School of Engineering, received a $500,000 CAREER award from the National Science Foundation to develop computational tools that improve our understanding of the human brain.

8 Jun 2021

Bacteria causing urinary tract infections can originate in meat-production chain

In young women, Staphylococcus saprophyticus is a main cause of urinary tract infections (UTI), reaching 20% prevalence. Understanding the epidemiology of this microorganism can help identify its origin, distribution, causes, and risk factors.

8 Jun 2021

New method successfully reversed male infertility in mice

The ability of stem cells to fix impaired functions of host tissues after transplantation has been a lifesaving breakthrough in treating previously incurable conditions. Much like a coin toss, however, the fate of the transplanted stem cells is unpredictable. They may choose self-renewal, grow into a different kind of tissue, or die.

8 Jun 2021

ACE2 functions as a gateway for COVID-19 virus

Normally, the ACE2 enzyme helps regulate our blood pressure. The enzyme sits on the surface of cells, including cells in the lungs, but in connection with COVID-19 it has been found that ACE2 also functions as a gateway for the virus.

8 Jun 2021

Fluorescence-based assay for detecting SARS-CoV-2 neutralizing antibodies

Researchers have developed a rapid assay to rapidly detect neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using an imaging technique they developed for the Ebola virus.

8 Jun 2021

Study explores link between intergenerational families and cognitive function among older Chinese Americans

Older Chinese immigrants who adjust to their new cultural environment by learning the language, following the country's media and socializing with local residents can reduce acculturation gap with their adult children and protect their cognitive function, according to a Rutgers study.

8 Jun 2021

New generative model has wide implications in developmental biology, regenerative medicine

Various forms of complex multicellular organisms have evolved on Earth, ranging from simple Volvox carterii which possess only 2 cell- types to us humans with more than 200 cell types. All originate from a single celled zygote, and their developmental processes depend on switch-like gene regulation.

8 Jun 2021

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

SGLT2 inhibitors (gliflozins) were developed as oral antidiabetics. They enhance urinary glucose excretion by inhibiting SGLT-2 (sodium-dependent glucose co-transporter-2) in the renal tubuli.

8 Jun 2021

Efforts to reduce patients' time on ventilator can spare their suffering and free up ICU resources

More active efforts to reduce patients' time on a ventilator in an ICU can both spare their suffering and free up intensive care resources, a thesis at the University of Gothenburg shows.

8 Jun 2021

Study examines how SARS CoV-2 aerosols travel through the lower lungs

When we inhale isolated coronavirus particles, more than 65% reach the deepest region of our lungs where damage to cells can lead to low blood oxygen levels, new research has discovered, and more of these aerosols reach the right lung than the left.

8 Jun 2021

Study offers a deeper understanding of the molecular basis for schizophrenia

A study conducted by a group of Brazilian researchers contributes to a deeper understanding of the molecular basis for schizophrenia, and potentially to the development of more specific and effective treatments for the disease.

8 Jun 2021

Scientists explain why space travel weakens the human immune system

Microgravity in space perturbs human physiology and is detrimental for astronaut health, a fact first realized during early Apollo missions when astronauts experienced inner ear disturbances, heart arrhythmia, low blood pressure, dehydration, and loss of calcium from their bones after their mission.

8 Jun 2021

Link between SARS-CoV-2 organotropism and kidney injury

It was clear at a relatively early stage of the pandemic that SARS-CoV-2 causes a wide range of symptoms; in addition to typical respiratory symptoms, patients also had neurological symptoms (starting with anosmia), gastrointestinal symptoms, elevated liver values, and renal, urinary or hematological changes, for example.

8 Jun 2021

Study shows how cowpea mosaic plant virus stimulates the immune system against cancer

Previous work by a team of researchers led by Steven N. Fiering, PhD, Immunology and Cancer Immunotherapy researcher at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center and Nicole Steinmetz, PhD, Jacobs School of Engineering and Moores Cancer Center, University of California San Diego, showed that a plant virus that does not infect mammals, cowpea mosaic plant virus (CPMV), when injected into cancerous tumors, strongly stimulated the immune system to attack and often eliminate the tumor.

8 Jun 2021

Researchers develop promising stem cell therapy to treat type 1 diabetes

Type 1 diabetes, which arises when the pancreas doesn't create enough insulin to control levels of glucose in the blood, is a disease that currently has no cure and is difficult for most patients to manage.

8 Jun 2021

Data from pre-adolescent brain activation study may clarify risk factors for mental health disorders

Youth brain activation data from the largest longitudinal neuroimaging study to date provides valuable new information on the cognitive processes and brain systems that underlie adolescent development and might contribute to mental and physical health challenges in adulthood.

8 Jun 2021

New blood test helps monitor patient’s response to cancer treatment

Cancer patients who are undergoing targeted therapy can look forward to a new blood test that could tell their doctors whether the treatment is working, within one day after the start of the treatment.

8 Jun 2021

Medical Research News

Study: COVID-19 produced more symptoms and complications than seasonal influenza in youths

Chemical engineers devise a simpler process to incorporate hydrophobic drugs into tablets

NIH researchers identify novel small molecule inhibitors of SARS-CoV-2 variants

New technology can explain the effect of genetic factors on brain structure, function

Bacteria causing urinary tract infections can originate in meat-production chain

New method successfully reversed male infertility in mice

ACE2 functions as a gateway for COVID-19 virus

Fluorescence-based assay for detecting SARS-CoV-2 neutralizing antibodies

Study explores link between intergenerational families and cognitive function among older Chinese Americans

New generative model has wide implications in developmental biology, regenerative medicine

Study reveals mechanisms by which SGLT2 inhibitors produce renoprotective effect

Efforts to reduce patients' time on ventilator can spare their suffering and free up ICU resources

Study examines how SARS CoV-2 aerosols travel through the lower lungs

Study offers a deeper understanding of the molecular basis for schizophrenia

Scientists explain why space travel weakens the human immune system

Link between SARS-CoV-2 organotropism and kidney injury

Study shows how cowpea mosaic plant virus stimulates the immune system against cancer

Researchers develop promising stem cell therapy to treat type 1 diabetes

Data from pre-adolescent brain activation study may clarify risk factors for mental health disorders

New blood test helps monitor patient’s response to cancer treatment

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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