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Study reveals a new form of muscular dystrophy associated with pathogenic changes in JAG2 gene

In about a quarter of patients with hereditary diseases, the cause of the disease remains unclear even after extensive genetic testing. One reason is that we still do not know enough about the function of many genes. Of the 30,000 known genes, just a little more than 4,000 have been found to be associated with hereditary diseases.

6 May 2021

Monocytes promote viral control during SARS-COV-2 infection

In a paper recently uploaded to the preprint server bioRxiv by Vanderheiden et al. (May 4th, 2021) the contribution of monocytes in promoting protective immunity from SARS-CoV-2 is investigated in a murine model, suggesting that CCR2 plays the role of an inflammation modulator in early infection.

6 May 2021

Study: Second vaccine dose still makes organ transplant recipients vulnerable to COVID-19

In a study published today in the Journal of the American Medical Association (JAMA), Johns Hopkins Medicine researchers show that although two doses of a vaccine against SARS-CoV-2 - the virus that causes COVID 19 - confers some protection for people who have received solid organ transplants, it's still not enough to enable them to dispense with masks, physical distancing and other safety measures.

6 May 2021

Nanoscope presents optical gene delivery, OCT-guided electrophysiology platforms at ARVO annual meeting

Nanoscope Technologies LLC, a biotechnology company developing gene therapies for treatment of retinal diseases, is featuring multiple scientific presentations highlighting its groundbreaking research on optical gene delivery for vision restoration and OCT-guided electrophysiology platforms for characterization of retinal degeneration and assessment of efficacy of cell-gene therapy at the 2021 ARVO annual (virtual) meeting, May 1-7.

5 May 2021

Researchers identify potent small molecule TMPRSS2 inhibitor against SARS-CoV-2

A team of scientists from the USA and Canada has recently identified and characterized a novel small-molecule compound inhibitor of cellular serine protease TMPRSS2, which shows significant antiviral potency against emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 May 2021

Novel pipeline identifies millions of molecular targets in SARS-CoV-2

Researchers in the United States have developed a novel pipeline for high-throughput, automated annotation of the genes, proteins and functional domains in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

5 May 2021

Prior MMR or Tdap vaccination may reduce risk of severe COVID-19

Researchers in the United States have shown that prior Measles-Mumps-Rubella (MMR) or Tetanus-Diphtheria-pertussis (Tdap) vaccination may reduce the risk of severe outcomes in patients with coronavirus disease 2019 (COVID-19).

5 May 2021

Majority of Black Canadians show severe depressive symptoms, study finds

The first mental health study of Black communities in Canada has found the majority of Black Canadians display severe depressive symptoms - women, even more so - with racial discrimination confirming the appearance of these signs for nearly all.

5 May 2021

Novel CBD analog alleviates pain in mouse model of chemotherapy-induced peripheral neuropathy

For patients with chronic pain, ineffective treatments, lowered work productivity, and other factors often coalesce, fueling feelings of hopelessness and anxiety and setting the stage for even bigger problems, including substance use disorders.

5 May 2021

Researchers show how low-protein diet during pregnancy can cause kidney problems in babies

Besides being underweight, babies born to women whose diet lacked sufficient protein during pregnancy tend to have kidney problems resulting from alterations that occurred while their organs were forming during the embryonic stage of their development.

5 May 2021

Repurposing an existing, cheap drug into long-acting injectable therapy to treat Covid-19

Researchers from the University of Liverpool have shown the potential of repurposing an existing and cheap drug into a long-acting injectable therapy that could be used to treat Covid-19.

5 May 2021

New service enables patients to recover safely at home, avoid hospitalization

A new service piloted at Penn Medicine allowed a proportion of patients to avoid hospitalization by providing them with greater support after visiting the emergency department.

5 May 2021

UIC researcher finds potential new way to treat chronic migraine

By discovering a potential new cellular mechanism for migraines, researchers may have also found a new way to treat chronic migraine.

5 May 2021

New genetic mutation increases risk for atrial fibrillation, heart failure in Black people

A new mutation found in a gene associated with an increased risk of atrial fibrillation poses a significantly increased risk for heart failure in Black people.

5 May 2021

Ultrasound technique provides a new way to diagnose circulation problems in the placenta

A team of researchers funded by the National Institutes of Health has developed a new ultrasound technique to monitor the placenta for impaired fetal blood flow early in pregnancy.

5 May 2021

Brain thinning in youth associated with psychosis

Subtle differences in the shape of the brain that are present in adolescence are associated with the development of psychosis, according to an international team led by neuroscientists at the University of Pittsburgh School of Medicine and Maastricht University in the Netherlands.

5 May 2021

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

Despite decades of research and investment, the genetic underpinnings of Alzheimer's disease are still largely unknown, stymieing drug development and early diagnosis efforts.

5 May 2021

New app enables faster treatment of patients suffering a heart attack

Patients suffering a heart attack received percutaneous coronary intervention (PCI), a procedure to clear blocked arteries in the heart, an average of 10 minutes faster after clinicians and paramedics began using an app to facilitate efficient hospital intakes for these patients, according to a study being presented at the American College of Cardiology's 70th Annual Scientific Session.

5 May 2021

Study: Only half of Americans with a history of heart disease get annual flu shot

People with heart disease are more likely to become seriously ill from the flu and other respiratory illnesses, including the coronavirus.

5 May 2021

Sleeping six to seven hours a night associated with more favorable heart health

People who clock six to seven hours of sleep a night had the lowest chance of dying from a heart attack or stroke when compared with those who got less or more sleep, according to a study being presented at the American College of Cardiology's 70th Annual Scientific Session.

5 May 2021

Medical Research News

Study reveals a new form of muscular dystrophy associated with pathogenic changes in JAG2 gene

Monocytes promote viral control during SARS-COV-2 infection

Study: Second vaccine dose still makes organ transplant recipients vulnerable to COVID-19

Nanoscope presents optical gene delivery, OCT-guided electrophysiology platforms at ARVO annual meeting

Researchers identify potent small molecule TMPRSS2 inhibitor against SARS-CoV-2

Novel pipeline identifies millions of molecular targets in SARS-CoV-2

Prior MMR or Tdap vaccination may reduce risk of severe COVID-19

Majority of Black Canadians show severe depressive symptoms, study finds

Novel CBD analog alleviates pain in mouse model of chemotherapy-induced peripheral neuropathy

Researchers show how low-protein diet during pregnancy can cause kidney problems in babies

Repurposing an existing, cheap drug into long-acting injectable therapy to treat Covid-19

New service enables patients to recover safely at home, avoid hospitalization

UIC researcher finds potential new way to treat chronic migraine

New genetic mutation increases risk for atrial fibrillation, heart failure in Black people

Ultrasound technique provides a new way to diagnose circulation problems in the placenta

Brain thinning in youth associated with psychosis

New $10.7 million project aims to study the genetic underpinnings of Alzheimer's disease

New app enables faster treatment of patients suffering a heart attack

Study: Only half of Americans with a history of heart disease get annual flu shot

Sleeping six to seven hours a night associated with more favorable heart health

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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