Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Study holds promise for malarial susceptibility test

Cell and animal studies conducted jointly by scientists at Johns Hopkins, Yale and other institutions have uncovered at least one important contributor to the severe anemia that kills almost half of the 2 million people worldwide who die each year of malaria.

12 May 2006

Corticosteroids may be linked to an increased risk for atrial fibrillation

High doses of medications known as corticosteroids may be linked to an increased risk for atrial fibrillation, a heart rhythm disorder characterized by an irregular heartbeat, according to an article in the May 8 issue of Archives of Internal Medicine.

9 May 2006

Effective gene suppression using small interfering RNA in hard-to-transfect human T cells

A technical advance in laboratory techniques may provide biology researchers broader access to RNA interference, a process of blocking the activity of targeted genes. RNA interference has recently emerged as an important tool in studying how genes function in normal biological processes and in disease.

9 May 2006

$Childhood arthritis increases the risk of fractures$

Childhood arthritis increases the risk of fractures

Childhood arthritis increases the risk of fractures, particularly during adolescence, according to a large study of British patient records. The researchers say that more targeted treatments promoting bone health would benefit patients with childhood-onset arthritis throughout their lifespan.

8 May 2006

The efficacy and safety of Rituximab in patients with active rheumatoid arthritis

Drugs aimed at suppressing inflammation-provoking cytokines--specifically those linked to T-cells--have improved the treatment of rheumatoid arthritis (RA), a chronic, inflammatory autoimmune disease. Still, the frequency of remission achieved by these biologic agents remains below 50 percent.

3 May 2006

Etanercept and chemo might reduce fatigue in cancer patients

Researchers here have found evidence that combining a drug typically used to treat rheumatoid arthritis with chemotherapy might help reduce fatigue and muscle wasting that often afflicts cancer patients.

3 May 2006

Cellular events leading to chondrocyte death after cartilage impact injury

Documented in extensive studies, backed by the anecdotal evidence of professional athletes, impact injury to joints causes degeneration of cartilage.

3 May 2006

Drug combo significantly more effective in reducing dyspepsia in arthritis patients

UCLA/VA researchers found that for arthritis patients, taking a combination of two drugs may be most effective in protecting against stomach upset called dyspepsia, which is a side effect of common pain medications.

3 May 2006

Study indicates how drug efficacy can be increased by manipulating the signalling mechanism

Researchers believe they have found a way to change the action of 60 percent of currently available medications, in some cases making them many times more effective, according to an article published in the April 21 edition of the journal Science. The discovery has the potential to improve treatments for diseases including heart disease, cancer, diabetes, depression and arthritis. The study describes a new way to manipulate perhaps the most important signaling mechanism in human cells: G-protein coupled receptors (GPCRs).

28 Apr 2006

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.

26 Apr 2006

Alternative anti-inflammatory drugs promise less cardiovascular problems

New type of anti-inflammatory drugs may reduce COX-2 cardiovascular problems, says Queen's researcher

25 Apr 2006

Swedish ACI method of cartilage repair gives excellent durability

As the population ages, arthritis will become more prevalent. It would be helpful to know more about the causes and treatments of cartilage wear.

25 Apr 2006

Foot problems change social behaviour - but it doesn't have to be that way

With the average person taking 9,000 steps per day -- more than 600 miles each year -- when feet start to hurt or change in shape, it can really impact a person's life. In fact, according to a new survey, of people who report having foot issues in the past five years, two out of three report that these foot issues, which range from blisters to bunions and heel pain, have changed the kind of shoes they wear, how active they are, where and how far they walk, and so on.

23 Apr 2006

Discovery points to more effective ways of regulating cell signalling

A discovery made at The Walter and Eliza Hall Institute provides new insights into enhancing the function of the protein SOCS3, which regulates the response of cells to external stimuli.

20 Apr 2006

Study could lead to development of differential treatments for pain in men versus women

A study conducted by investigators at Georgia State University and the Atlanta-based Center for Behavioral Neuroscience (CBN) reports that anatomical and functional differences in the brain may explain sex differences in the experience of pain and in the effects of certain drugs on pain.

19 Apr 2006

Herbal medicines may be as effective as pain medication for short-term low back pain

The herbal preparations devil's claw, white willow bark and cayenne plasters may be as effective as pain medication for short-term low back pain and are better than placebo, a new systematic review of studies has found.

18 Apr 2006

Possible alternatives found for Vioxx and Celebrex

According to Canadian and American researchers they have identified one reason why drugs like Celebrex and Vioxx - once popular for the treatment of pain and inflammation - cause heart problems.

18 Apr 2006

Researchers clarify the mechanism by which drugs like Celebrex and Vioxx cause heart problems

Researchers at the University of Pennsylvania School of Medicine have clarified the mechanism by which drugs like Celebrex and Vioxx cause heart problems, in multiple animal models.

18 Apr 2006

217 new targets for anti-cancer drugs

By identifying novel genes critical to cancer progression, biologists at the U.S. Department of Energy's Argonne National Laboratory have expanded the number of drug targets researchers have available for study to find ways to stop tumors in their tracks.

18 Apr 2006

Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6

A novel growth factor significantly improves the ability of specialized stem cells derived from human fat to be transformed into cartilage cells, according to Duke University Medical Center and Pratt School of Engineering researchers.

16 Apr 2006

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Study holds promise for malarial susceptibility test

Corticosteroids may be linked to an increased risk for atrial fibrillation

Effective gene suppression using small interfering RNA in hard-to-transfect human T cells

Childhood arthritis increases the risk of fractures

The efficacy and safety of Rituximab in patients with active rheumatoid arthritis

Etanercept and chemo might reduce fatigue in cancer patients

Cellular events leading to chondrocyte death after cartilage impact injury

Drug combo significantly more effective in reducing dyspepsia in arthritis patients

Study indicates how drug efficacy can be increased by manipulating the signalling mechanism

Enhancing the function of the protein SOCS3 could be a more effective way to regulate cell responses

Alternative anti-inflammatory drugs promise less cardiovascular problems

Swedish ACI method of cartilage repair gives excellent durability

Foot problems change social behaviour - but it doesn't have to be that way

Discovery points to more effective ways of regulating cell signalling

Study could lead to development of differential treatments for pain in men versus women

Herbal medicines may be as effective as pain medication for short-term low back pain

Possible alternatives found for Vioxx and Celebrex

Researchers clarify the mechanism by which drugs like Celebrex and Vioxx cause heart problems

217 new targets for anti-cancer drugs

Potent induction of chondrocytic differentiation of human adipose-derived adult stem cells by bone morphogenetic protein 6

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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