CRISPR News and Research

Latest CRISPR News and Research

ELRIG: Bringing Life Sciences and Drug Discovery Communities Together

We spoke to ELRIG about the evolving landscape of the drug discovery sector, and what actions they are taking to continue to support individuals in this space.

11 Nov 2022

New CRISPR approach is a leap forward in developing personalized treatment for cancer

For the first time, scientists have used CRISPR technology to insert genes that allow immune cells to focus their attack on cancer cells, potentially leaving normal cells unharmed and increasing the effectiveness of immunotherapy.

10 Nov 2022

Treatment using CRISPR genome editing alleviates swelling attacks in hereditary angioedema patients

Hereditary angioedema (HAE) is a rare, genetic disorder characterized by severe, recurring, and unpredictable swelling attacks in various organs and tissues of the body, which can be painful, debilitating, and life-threatening.

10 Nov 2022

Scientists determine 5,072 essential human genes

In a recent study published in the journal Cell, researchers examined the phenotypic landscape of multiple elusive essential human genes to create a detailed genotype-phenotype resource outlining the phenotypic consequences of disrupting fundamental cellular processes.

8 Nov 2022

Novel gene editing therapy reduces circulating TTR protein levels in patients with ATTR amyloid cardiomyopathy

A single IV infusion of NTLA-2001, a novel CRISPR/Cas9-based gene editing therapy, significantly reduced circulating transthyretin (TTR) protein levels in patients with ATTR amyloid cardiomyopathy, a progressive and fatal cause of heart failure, according to late-breaking research presented today at the American Heart Association’s Scientific Sessions 2022.

7 Nov 2022

Study confirms the implication of Mib1 mutations in non-compaction cardiomyopathy

Non-compaction cardiomyopathy is a heart condition caused by defects that arise during fetal development and can have diverse health impacts in affected individuals, including sudden cardiac death.

7 Nov 2022

Study finds possible treatment strategy for Feingold syndrome type 1

A decrease in protein synthesis in cells of the developing gut contributes to a rare genetic disorder, and an inexpensive nutritional supplement may help reverse that decrease, according to a new study publishing November 1st in the open access journal PLOS Biology by Yun-Fei Li of Zhejiang University School of Medicine in Hangzhou, China, and colleagues. The finding is an advance in understanding the pathogenesis of the disease, and may lead to new treatments.

2 Nov 2022

New control system could be used to finely tune the production of useful proteins

Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.

1 Nov 2022

Specific stem cell protein found to be involved in the recurrence of medulloblastoma

The malignant brain tumor type medulloblastoma can become resistant to therapy which can cause relapse. Researchers at Uppsala University have discovered a certain protein that makes tumor cells resting and insensitive to radiation treatment.

28 Oct 2022

Yeast reveals a key mechanism in how genes are controlled

Yeast, that simple organism essential to making beer and bread, has revealed for Cornell University researchers a key mechanism in how genes are controlled.

28 Oct 2022

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with resistant leukaemia, who had otherwise exhausted all available therapies.

27 Oct 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

Discovery points to a new understanding of Stargardt disease progression

Using a new stem-cell-based model made from skin cells, scientists found the first direct evidence that Stargardt-related ABCA4 gene mutations affect a layer of cells in the eye called the retinal pigment epithelium (RPE).

27 Oct 2022

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

A fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.

27 Oct 2022

New studies point to a broadly applicable treatment for neurodegenerative diseases

Two new studies from Washington University School of Medicine in St. Louis support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system.

26 Oct 2022

CRISPR News and Research

Latest CRISPR News and Research

ELRIG: Bringing Life Sciences and Drug Discovery Communities Together

New CRISPR approach is a leap forward in developing personalized treatment for cancer

Treatment using CRISPR genome editing alleviates swelling attacks in hereditary angioedema patients

Scientists determine 5,072 essential human genes

Novel gene editing therapy reduces circulating TTR protein levels in patients with ATTR amyloid cardiomyopathy

Study confirms the implication of Mib1 mutations in non-compaction cardiomyopathy

Study finds possible treatment strategy for Feingold syndrome type 1

New control system could be used to finely tune the production of useful proteins

Specific stem cell protein found to be involved in the recurrence of medulloblastoma

Yeast reveals a key mechanism in how genes are controlled

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Discovery points to a new understanding of Stargardt disease progression

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

New studies point to a broadly applicable treatment for neurodegenerative diseases

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Researchers set sights on a new therapeutic target for aggressive breast cancer

Celebrating the Alderley Park Grand Opening

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

Butterfly wing pattern ground plan is manipulated by non-coding regulatory DNA, study says

The art of CRISPR: The power and promise of gene editing eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?