Gene News and Research

Latest Gene News and Research

Gene ZSCAN4 may help treat Down syndrome

For people with Down syndrome, news from Elixirgen, LLC may brighten their day. The biotechnology company, located in the Science + Technology Park at Johns Hopkins, has outlined one of the best potential therapies yet for people with Down syndrome and other chromosome disorders in a paper entitled, "Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures," published in the journal DNA Research.

31 Aug 2015

Regen BioPharma develops novel means of delivering RGBP-248 gene silencing nucleic acid to liver tumors

Regen BioPharma, Inc. announced today development of a novel means of delivering its patented (US Patent 8,263,571) gene silencing nucleic acid, RGBP-248, to liver tumors utilizing a clinically approved formulation as delivery system. The product in development overcomes previous hurdles with gene silencing therapeutics in which the gene silencing drug had to be delivered throughout the whole body.

31 Aug 2015

People with BPD traits have lowered activity in brain regions that support empathy

Those with borderline personality disorder, or BPD, a mental illness marked by unstable moods, often experience trouble maintaining interpersonal relationships. New research from the University of Georgia indicates that this may have to do with lowered brain activity in regions important for empathy in individuals with borderline personality traits.

29 Aug 2015

Fetal microchimerism could be a subtle and dizzyingly complex puzzle

Parents go to great lengths to ensure the health and well-being of their developing offspring. The favor, however, may not always be returned.

29 Aug 2015

KAIST scientists predict how biological circuits sustain rhythms

Our bodies have a variety of biological clocks that follow rhythms or oscillations with periods ranging from seconds to days. For example, our hearts beat every second, and cells divide periodically. The circadian clock located in the hypothalamus generates twenty-four hour rhythms, timing our sleep and hormone release.

29 Aug 2015

Researchers provide new insights into biology of aging, age-related diseases

The scientific team of a new biotech company Gero in collaboration with one of the leading academics in the field of aging Prof. Robert J. Shmookler Reis (current world record holder in life extension for model animals - 10 fold for nematodes) has recently brought new insights into biology of aging and age-related diseases, primarily, around the stability and stress resistance of certain gene regulatory networks.

28 Aug 2015

Findings reveal a new way to prevent meningitis

The fungus Cryptococcus causes meningitis, a brain disease that kills about 1 million people each year — mainly those with impaired immune systems due to AIDS, cancer treatment or an organ transplant.

28 Aug 2015

Genetic test that predicts recurrence of breast cancer may impact use of chemotherapy

A genetic test that helps predict whether some women's breast cancer will recur might influence how chemotherapy is used, according to a study from Duke Medicine.

28 Aug 2015

Researchers identify drugs that may enhance ability of TKI dasatinib to kill human cancer cells

Researchers have discovered how a common mutation in a high-risk leukemia subtype drives the cancer's aggressiveness and have identified drugs that may work with existing precision medicines to improve survival. St. Jude Children's Research Hospital scientists led the study, which was published online today in the journal Cancer Cell.

28 Aug 2015

Melatonin hormone can help prevent cardiovascular disease risk in children born through ART

Studies are revealing that children born through assisted reproductive technologies (ART) have a higher risk of developing cardiovascular disease. The increased risk is due to changes in the expression of the genes important for vascular health. These studies suggest that the composition of the solutions in which embryo fertilization and culturing are done is to blame.

28 Aug 2015

Researchers identify new virus that plays role in rare type of liver cancer

More than a cause of a simple infection, viruses are often involved in the development of serious diseases. Such is the case with liver cancer, which often develops in an organ that has been weakened by hepatitis B or C virus.

28 Aug 2015

Experimental gene therapy may prevent neuronal degeneration in patients with Alzheimer's disease

Degenerating neurons in patients with Alzheimer's disease (AD) measurably responded to an experimental gene therapy in which nerve growth factor (NGF) was injected into their brains, report researchers at University of California, San Diego School of Medicine in the current issue of JAMA Neurology.

28 Aug 2015

Researchers find way to trigger 'virus alert' that may help boost drug's ability to prevent cancer cells

Working with human cancer cell lines and mice, researchers at the Johns Hopkins Kimmel Cancer Center and elsewhere have found a way to trigger a type of immune system "virus alert" that may one day boost cancer patients' response to immunotherapy drugs. An increasingly promising focus of cancer research, the drugs are designed to disarm cancer cells' ability to avoid detection and destruction by the immune system.

27 Aug 2015

PFF, Veracyte partner on U.S. survey exploring patients' diagnostic experiences with interstitial lung diseases

The Pulmonary Fibrosis Foundation and Veracyte, Inc. announced that the organizations are partnering on a U.S. patient survey to advance understanding of patients' diagnostic experiences with interstitial lung diseases (ILDs), including idiopathic pulmonary fibrosis (IPF).

27 Aug 2015

NTNU researchers find link between aggression and gene variant in children

Some children react more strongly to negative experiences than others. Researchers from the Norwegian University of Science and Technology have found a link between aggression and variants of a particular gene.

27 Aug 2015

New study describes multi-method strategy to improve detection of PMS2 gene mutations in Lynch syndrome

About 3% of colorectal cancers are due to Lynch syndrome, an inherited cancer susceptibility syndrome that predisposes individuals to various cancers. Close blood relatives of patients with Lynch syndrome have a 50% chance of inheritance. The role that PMS2 genetic mutations play in Lynch syndrome has been underestimated in part due to technological limitations.

27 Aug 2015

Researchers design online database to help researchers identify cancer gene mutations

Many clinical trials use genome sequencing to learn which gene mutations are present in a patient's tumor cells. The question is important because targeting the right mutations with the right drugs can stop cancer in its tracks. But it can be difficult to determine whether there is evidence in the medical literature that particular mutations might drive cancer growth and could be targeted by therapy, and which mutations are of no consequence.

27 Aug 2015

Gene News and Research

Latest Gene News and Research

Gene ZSCAN4 may help treat Down syndrome

Regen BioPharma develops novel means of delivering RGBP-248 gene silencing nucleic acid to liver tumors

People with BPD traits have lowered activity in brain regions that support empathy

Fetal microchimerism could be a subtle and dizzyingly complex puzzle

KAIST scientists predict how biological circuits sustain rhythms

Researchers provide new insights into biology of aging, age-related diseases

Findings reveal a new way to prevent meningitis

Genetic test that predicts recurrence of breast cancer may impact use of chemotherapy

Researchers identify drugs that may enhance ability of TKI dasatinib to kill human cancer cells

Melatonin hormone can help prevent cardiovascular disease risk in children born through ART

Researchers identify new virus that plays role in rare type of liver cancer

Experimental gene therapy may prevent neuronal degeneration in patients with Alzheimer's disease

Researchers find way to trigger 'virus alert' that may help boost drug's ability to prevent cancer cells

PFF, Veracyte partner on U.S. survey exploring patients' diagnostic experiences with interstitial lung diseases

NTNU researchers find link between aggression and gene variant in children

New study describes multi-method strategy to improve detection of PMS2 gene mutations in Lynch syndrome

Researchers design online database to help researchers identify cancer gene mutations

Two studies highlight important new discovery around most common genetic defect linked to ALS

Common gene mutation may cause brain damage associated with ALS and FTD

UCSF study reveals molecular timing mechanism of stem cells

Industry Focus: Cell & Gene Therapy eBook

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Todd Bauman and Chris Povich