Gene News and Research

Latest Gene News and Research

Existing compound offers hope for slowing Huntington's disease progression

Currently, there is no treatment to halt the progression of Huntington's disease (HD), a fatal genetic disorder that slowly robs sufferers of their physical and mental abilities. Now, researchers at University of California, San Diego School of Medicine have discovered that an existing compound, previously tested for diabetes, offers hope for slowing HD and its symptoms.

8 Dec 2015

Plasmacytoid dendritic cells may not contribute to late-stage lupus

For years, biomedical researchers have suspected that a specific set of immune cells are responsible for causing disease in lupus patients, but until now they haven't known for sure one way or the other.

8 Dec 2015

CTTV launches new web platform for identifying therapeutic targets

The Centre for Therapeutic Target Validation (CTTV) has launched a new web platform for life-science researchers that helps them identify therapeutic targets for new and repurposed medicines. Today's launch underscores the CTTV's commitment to share its data openly to benefit the broader scientific community.

8 Dec 2015

NEK7 enzyme acts as on-off switch in innate immune system

UT Southwestern Medical Center and California researchers today provide the first report that an enzyme previously known solely for its role in cell division also acts as an on-off switch in the innate immune system -- the body's first defense against infection.

8 Dec 2015

Stanford researchers invent new technique to dramatically accelerate protein evolution

All living things require proteins, members of a vast family of molecules that nature "makes to order" according to the blueprints in DNA.

8 Dec 2015

First targeted treatment to improve survival of high-risk patients with acute myeloid leukemia

Midostaurin added to standard chemotherapy is the first targeted treatment to improve survival of a high-risk, genetically defined subgroup of patients with acute myeloid leukemia (AML), reported Dr. Richard Stone, of Dana-Farber Cancer Institute, on behalf of the Alliance for Clinical Trials in Oncology group, in a plenary session at the 57th American Society of Hematology Annual Meeting and Exposition in Orlando.

8 Dec 2015

Study: Certain characteristics can lead to therapy-related leukemia in breast cancer survivors

A new analysis indicates that certain characteristics may increase a breast cancer survivor’s risk of developing leukemia after undergoing chemotherapy and/or radiation. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings are a first step toward finding ways to prevent this serious and potentially life-threatening treatment-related complication.

8 Dec 2015

Faulty gene function responsible for reducing survival times of leukaemia patients

Researchers have identified a genetic fault in some leukaemia patients that could be responsible for halving survival times after diagnosis compared to patients without the fault – an average reduction from 16 years to seven years. T

8 Dec 2015

Researchers reveal potential for exploring new treatment options for triple-negative breast cancer

Researchers from Caris Life Sciences and Fox Chase Cancer Center – Temple Health announced the presentation of two studies revealing the potential for exploring new therapeutic options for triple-negative breast cancer (TNBC) at the 2015 San Antonio Breast Cancer Symposium.

7 Dec 2015

Research shows significant step toward improving outcomes, reducing treatment burden for SCD patients

Emerging therapies and promising new insights in the treatment of sickle cell disease represent a significant step toward improving outcomes and reducing the treatment burden for affected children and adults. Studies reporting these advances will be presented today at the 57th American Society of Hematology Annual Meeting and Exposition.

7 Dec 2015

New approaches to treating leukemia, lymphoma and myeloma

New, highly targeted treatment approaches for leukemia, lymphoma, and myeloma to be presented today at the 57th American Society of Hematology Annual Meeting and Exposition represent a tremendous expansion of oral and intravenous therapy options for patients with blood cancers.

7 Dec 2015

Cell Therapy Catapult’s 2015 Annual Review highlights key achievements across UK’s health and economy

The Cell Therapy Catapult, the UK organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the release of their 2015 Annual Review.

7 Dec 2015

Gene therapy shows promise in children with Wiskott-Aldrich syndrome

Researchers reported promising preliminary outcomes for the first four children enrolled in a U.S. gene therapy trial for Wiskott-Aldrich syndrome (WAS), a life-threatening genetic blood and immune disorder, at the 57th annual meeting of the American Society of Hematology (abstract #260).

7 Dec 2015

Gene therapy can restore immune systems of children and young adults with SCID-X1

Gene therapy can safely rebuild the immune systems of older children and young adults with X-linked severe combined immunodeficiency (SCID-X1), a rare inherited disorder that primarily affects males, scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, have found.

7 Dec 2015

Research reveals genetic variants linked to treatment-related complications in children with blood diseases

Research to be presented today at the 57th American Society of Hematology Annual Meeting and Exposition reveals genetic variants that are associated with disease severity and treatment-related complications in children with blood diseases.

7 Dec 2015

Genetic variations associated with increased risk for osteonecrosis in young ALL patients

Variations in genes involved in normal bone development are associated with an 8- to 15-fold increased risk for osteonecrosis in young patients with acute lymphoblastic leukemia (ALL), according to research led by St. Jude Children's Research Hospital and Children's Oncology Group investigators.

7 Dec 2015

Experimental gene therapy may improve health outcomes for patients with some forms of blood disorders

New research adds to a growing body of evidence that gene therapy, an experimental technique that involves correcting or replacing a person's mutated or malfunctioning genes, may improve health outcomes for patients with inherited bleeding and immune disorders as well as some forms of blood cancer.

7 Dec 2015

Study identifies new recurrent genetic mutations involved in origin of AML

Mariam Ibáñez, lecturer at Universidad Cardenal Herrera CEU (CEU Cardenal Herrera University, UCH-CEU) and biologist at "La Fe" Hospital in Valencia used massive sequencing techniques to identify new recurrent genes mutations involved in the origin of acute myelogenous leukemia (AML).

1 Dec 2015

Lexicon announces top-line results from TELECAST Phase 3 study of telotristat etiprate

Lexicon Pharmaceuticals, Inc. announced today that top-line data from its TELECAST Phase 3 study showed results of telotristat etiprate in treating carcinoid syndrome in cancer patients with metastatic neuroendocrine tumors consistent with the clinical benefit observed in its pivotal TELESTAR study.

1 Dec 2015

Discovery may lead to potential new therapeutic approach to eradicate blood cancers

An international team of scientists, headed by researchers at UC San Diego School of Medicine and UC San Diego Moores Cancer Center, report that decreases in a specific group of proteins trigger changes in the cancer microenvironment that accelerate growth and development of therapy-resistant cancer stem cells (CSCs).

1 Dec 2015

Gene News and Research

Latest Gene News and Research

Existing compound offers hope for slowing Huntington's disease progression

Plasmacytoid dendritic cells may not contribute to late-stage lupus

CTTV launches new web platform for identifying therapeutic targets

NEK7 enzyme acts as on-off switch in innate immune system

Stanford researchers invent new technique to dramatically accelerate protein evolution

First targeted treatment to improve survival of high-risk patients with acute myeloid leukemia

Study: Certain characteristics can lead to therapy-related leukemia in breast cancer survivors

Faulty gene function responsible for reducing survival times of leukaemia patients

Researchers reveal potential for exploring new treatment options for triple-negative breast cancer

Research shows significant step toward improving outcomes, reducing treatment burden for SCD patients

New approaches to treating leukemia, lymphoma and myeloma

Cell Therapy Catapult’s 2015 Annual Review highlights key achievements across UK’s health and economy

Gene therapy shows promise in children with Wiskott-Aldrich syndrome

Gene therapy can restore immune systems of children and young adults with SCID-X1

Research reveals genetic variants linked to treatment-related complications in children with blood diseases

Genetic variations associated with increased risk for osteonecrosis in young ALL patients

Experimental gene therapy may improve health outcomes for patients with some forms of blood disorders

Study identifies new recurrent genetic mutations involved in origin of AML

Lexicon announces top-line results from TELECAST Phase 3 study of telotristat etiprate

Discovery may lead to potential new therapeutic approach to eradicate blood cancers

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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